Journals / Turkish Journal of Medical Sciences / 2021 / Cilt: 51 - Sayı: 4

Investigation of the effects of propofol/ketamine versus propofol/fentanyl on nauseavomiting administered for sedation in children undergoing magnetic resonance imaging: a prospective randomized double-blinded study

Pages
2120–2126
Publication Date
2022-11-06
DOI
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Conclusion: In our study, we showed that the vomiting rate was higher in the 1st hour in Group K compared to Group F.Key words: Magnetic resonance imaging, child, ketamine, fentanyl, deep sedation, propofol

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: In this study, we aimed to compare the effects of propofol-ketamine and propofol-fentanyl sedations on postprocedure nausea-vomiting in children undergoing magnetic resonance imaging (MRI).
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Key Findings & Data:Materials and methods: This study included 100 pediatric patients (2–10 years old) who had propofol-ketamine and propofol-fentanyl for sedation to undergo MRI.
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Conclusion & Impact:Conclusion: In our study, we showed that the vomiting rate was higher in the 1st hour in Group K compared to Group F.Key words: Magnetic resonance imaging, child, ketamine, fentanyl, deep sedation, propofol
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: In this study, we aimed to compare the effects of propofol-ketamine and propofol-fentanyl sedations on postprocedure nausea-vomiting in children undergoing magnetic resonance imaging (MRI). Materials and methods: This study included 100 pediatric patients (2–10 years old) who had propofol-ketamine and propofol-fentanyl for sedation to undergo MRI. The patients were divided into two groups, and sedation was performed through propofol-ketamine (Group K; n = 50) or propofol-fentanyl (Group F; n = 50). For sedation induction, intravenous (IV) bolus of 1.2 mg/kg propofol and 1 mg/kg ketamine were administered in Group K, IV bolus of 1.2 mg/kg propofol, and 1 µg/kg fentanyl in Group F. All patients received 0.5 mg/kg IV bolus propofol in additional doses when the Ramsay Sedation Score (RSS) was below 4 for maintenance. Perioperative heart rate, systolic arterial pressure, peripheral oxygen saturation, respiratory rate, and nausea-vomiting scores were recorded for each patient. Results: There was no difference between the groups in terms of nausea incidences at the 1st hour. However, the rate of vomiting was significantly higher in Group K. Conclusion: In our study, we showed that the vomiting rate was higher in the 1st hour in Group K compared to Group F.Key words: Magnetic resonance imaging, child, ketamine, fentanyl, deep sedation, propofol

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Cite This Article

ÜLGEY, A., GÜRCAN, H. S., GERGİN, Ö. Ö., PEHLİVAN, S. S., YILDIZ, K. (2022). Investigation of the effects of propofol/ketamine versus propofol/fentanyl on nauseavomiting administered for sedation in children undergoing magnetic resonance imaging: a prospective randomized double-blinded study. Turkish Journal of Medical Sciences, Cilt: 51 - Sayı: 4, 2120–2126. https://ajindex.com/articles/609584

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