Journals / Turkish Journal of Medical Sciences / 2021 / Cilt: 51 - Sayı: 3

Evaluation of the relationship between cranial magnetic resonance imaging findings and clinical status in children with cerebral palsy

Pages
1296–1301
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

While pathology was observed mostly in cranial MRI in cases of CP with similar clinical features, the fact that cranial MRI was completely normal for 14.5% of the cases suggests that there may be some pathologies that we could not identify with today’s imaging technology.Key words: Cerebral palsy, comorbidity, gross motor function, cranial MRI

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: The objective of this study was to evaluate the relationship between cranial magnetic resonance imaging (MRI) findings and clinical features in cerebral palsy (CP).
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Key Findings & Data:Materials and methods: Children aged 3 to 18 years, who were followed with the diagnosis of CP between January 2012 and September 2015, were included.
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Conclusion & Impact:While pathology was observed mostly in cranial MRI in cases of CP with similar clinical features, the fact that cranial MRI was completely normal for 14.5% of the cases suggests that there may be some pathologies that we could not identify with today’s imaging technology.Key words: Cerebral palsy, comorbidity, gross motor function, cranial MRI
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Background/aim: The objective of this study was to evaluate the relationship between cranial magnetic resonance imaging (MRI) findings and clinical features in cerebral palsy (CP). Materials and methods: Children aged 3 to 18 years, who were followed with the diagnosis of CP between January 2012 and September 2015, were included. The type of CP was classified using the European Cerebral Palsy Monitoring Group’s classification system and then, patients were divided into two groups as spastic or nonspastic groups. The Gross Motor Function Classification System (GMFCS) was used to determine the level of mobility. According to the GMFCS, levels 1, 2, and 3 were grouped as mobile, and levels 4 and 5 were grouped as immobile. Cranial MRI findings were reevaluated by a voluntarily radiologist and grouped as periventricular leukomalacia (PVL) (grades 1, 2, and 3), cerebral atrophy, migration anomaly, cerebellar involvement, basal ganglion involvement, and normal MRI findings. Results: Sixty-two patients were enrolled. The rate of mobile patients did not differ between the spastic and nonspastic groups. The incidence of PVL was significantly higher in cases of prematurity and spastic CP (p < 0.05). The rate of mobilization was significantly lower and the rate of epilepsy was significantly higher in patients with PVL. Immobile patients were more common among cases of grade 3 PVL (p < 0.05). Conclusion: The most common cranial MRI pathology was PVL, and the presence of PVL and its grade might help clinically assess the patient’s CP type and level of mobilization. While pathology was observed mostly in cranial MRI in cases of CP with similar clinical features, the fact that cranial MRI was completely normal for 14.5% of the cases suggests that there may be some pathologies that we could not identify with today’s imaging technology.Key words: Cerebral palsy, comorbidity, gross motor function, cranial MRI

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Cite This Article

ÖZTEKİN, Ö., SARIOĞLU, F. C., SARIOĞLU, B., ŞIK, N. (2022). Evaluation of the relationship between cranial magnetic resonance imaging findings and clinical status in children with cerebral palsy. Turkish Journal of Medical Sciences, Cilt: 51 - Sayı: 3, 1296–1301. https://ajindex.com/articles/609558

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References (4)

  1. Rosenbaum PL, Palisano RJ, Bartlett DJ, Galuppi BE, Russell DJ. Development of the gross motor function classification system for cerebral palsy. Developmental Medicine & Child Neurology 2008; 50 (4): 249-253. doi: 10.1111/j.1469- 8749.2008.02045.x Epub 2008 Mar 1
  2. Sellier E, Platt MJ, Andersen GL, Krägeloh-Mann I, De La Cruz et al. Decreasing prevalence in cerebral palsy: a multi-site European population-based study, 1980 to 2003. Developmental Medicine & Child Neurology 2016; 58 (1): 85-92. doi: 10.1111/dmcn.12865 Epub 2015 Aug 28
  3. Galea C, McIntyre S, Smithers-Sheedy H, Reid SM, Gibson C et al. Cerebral palsy trends in Australia (1995-2009): a populationbased observational study. Developmental Medicine & Child Neurology 2019; 61 (2): 186-193. doi: 10.1111/dmcn.14011 4. Ashwal S, Russman BS, Blasco PA, Miller G, Sandler A et al. Practice parameter: diagnostic assessment of the child with cerebral palsy: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2004; 62 (6): 851-863. doi: 10.1212/01.wnl.0000117981.35364.1b 5. Korzeniewski SJ, Birbeck G, DeLano MC, Potchen MJ, Paneth N. A systematic review of neuroimaging for cerebral palsy. Journal of Child Neurology 2008; 23 (2): 216-227. doi: 10.1177/0883073807307983 6. Zarrinkalam R, Russo RN, Gibson CS, Essen P, Peek AK et al. CP or not CP? A review of diagnoses in a cerebral palsy register. Pediatric Neurology 2010; 42(3): 177-180. doi:10.1016/j. pediatrneurol.2009.09.001 7. Bax M, Tydeman C, Flodmark O. Clinical and MRI correlates of cerebral palsy: the European Cerebral Palsy Study. JAMA 2006; 296(13): 1602-1608. doi: 10.1001/jama.296.13.1602 8. Palisano RJ, Rosenbaum P, Walter S, Russell D, Wood E et al. Development and reliability of a system to classify gross motor function in children with cerebral palsy. Developmental Medicine & Child Neurology 1997; 39 (4): 214- 223. doi: 10.1111/j.1469-8749.1997.tb07414.x 9. Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M et al. A report: the definition and classification of cerebral palsy April 2006. Developmental Medicine & Child Neurology. Supplement 2007; 109: 8-14
  4. Wichers MJ, Odding E, Stam HJ, Van Nieuwenhuizen O. Clinical presentation associated disorders and aetiological moments in cerebral palsy: A Dutch population-based study. Disability and Rehabilitation 2005; 27 (10): 583-589. doi: 10.1080/09638280400018445 11. Surveillance of Cerebral