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Journals / Turkish Journal of Medical Sciences / 2021 / Cilt: 51 - Sayı: 2

Evaluation of serum anti-Müllerian hormone levels in women with Hashimoto thyroiditis in the reproductive age

Erman ÇAKAL
Muhammed Erkam SENCAR
Murat ÇALAPKULU
İlknur ÖZTÜRK ÜNSAL
Sema HEPŞEN
Ali YALÇINDAĞ
Pages
716–721
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Ovarian reserve evaluated by serum AMH concentration is affected by thyroid autoimmunity independently of antithyroid antibodies type or titers.Key words: Hashimoto thyroiditis, anti-Müllerian hormone, ovarian reserve, miscarriage

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: Autoimmune thyroid disease in women is associated with subfertility and early pregnancy loss, and patients with primary ovarian insufficiency have a high prevalence of thyroid autoimmune disorders.
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Key Findings & Data:Materials and methods: Levels of serum thyroid stimulating hormones, thyroid autoantibodies, and anti-Müllerian hormone (AMH) were measured in women with HT and a healthy control group between 2018 and 2019.
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Conclusion & Impact:Conclusion: Ovarian reserve evaluated by serum AMH concentration is affected by thyroid autoimmunity independently of antithyroid antibodies type or titers.Key words: Hashimoto thyroiditis, anti-Müllerian hormone, ovarian reserve, miscarriage
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Background/aim: Autoimmune thyroid disease in women is associated with subfertility and early pregnancy loss, and patients with primary ovarian insufficiency have a high prevalence of thyroid autoimmune disorders. The aim of this study was to investigate the association between Hashimoto thyroiditis (HT) and ovarian reserve. Materials and methods: Levels of serum thyroid stimulating hormones, thyroid autoantibodies, and anti-Müllerian hormone (AMH) were measured in women with HT and a healthy control group between 2018 and 2019. Results: Evaluation was made of 108 premenopausal women with HT, and a control group of 172 healthy females with normal antithyroid antibody levels and thyroid function. Serum AMH levels were determined to be significantly lower in the HT group compared to the control group. Conclusion: Ovarian reserve evaluated by serum AMH concentration is affected by thyroid autoimmunity independently of antithyroid antibodies type or titers.Key words: Hashimoto thyroiditis, anti-Müllerian hormone, ovarian reserve, miscarriage

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Cite This Article

ÇAKAL, E., SENCAR, M. E., ÇALAPKULU, M., ÜNSAL, İ. Ö., HEPŞEN, S., YALÇINDAĞ, A. (2022). Evaluation of serum anti-Müllerian hormone levels in women with Hashimoto thyroiditis in the reproductive age. Turkish Journal of Medical Sciences, Cilt: 51 - Sayı: 2, 716–721. https://ajindex.com/articles/609544

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