Journals / Turkish Journal of Medical Sciences / 2021 / Cilt: 51 - Sayı: Özel Sayı 1

Pregnancy and COVID-19: prevention, vaccination, therapy, and beyond

Pages
3312–3326
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, an individualized approach should be provided by a multidisciplinary team for the management of pregnant women with COVID-19 to achieve favorable outcomes.Key words: COVID-19, obstetric complications, pregnancy, SARS-CoV-2, vaccines

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has alarmed the world since its first emergence.
📊
Key Findings & Data:As pregnancy is characterized by significant changes in cardiovascular, respiratory, endocrine, and immunological systems, there are concerns on issues like the course of disease in pregnant women, safety of medications, route of delivery and risk of obstetric complications.
💡
Conclusion & Impact:In conclusion, an individualized approach should be provided by a multidisciplinary team for the management of pregnant women with COVID-19 to achieve favorable outcomes.Key words: COVID-19, obstetric complications, pregnancy, SARS-CoV-2, vaccines
🔬Design:Review & Systematic Survey
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has alarmed the world since its first emergence. As pregnancy is characterized by significant changes in cardiovascular, respiratory, endocrine, and immunological systems, there are concerns on issues like the course of disease in pregnant women, safety of medications, route of delivery and risk of obstetric complications. The aim of this review is to summarize the current literature in the management of pregnant women during the COVID-19 pandemic. Although more than 90% of pregnant women with COVID-19 recover without serious morbidity, rapid deterioration of disease and higher rates of obstetric complications may be observed. The risk of vertical transmission has not been clearly revealed yet. Decreasing the number of prenatal visits, shortening the time allocated for the examinations, active use of telemedicine services, limiting the number of persons in healthcare settings, combining prenatal tests in the same visit, restricting visitors during the visits, providing a safe environment in healthcare facilities, strict hygiene control, and providing personal protective equipment during the visits are the main strategies to control the spread of disease according to current guidelines. Although new medication alternatives are being proposed every day for the treatment of COVID-19, our knowledge about the use of most of these drugs in pregnancy is limited. Preliminary results are promising for the administration of SARS-CoV-2 vaccines in the pregnant population. Timing of delivery should be decided based on maternal health condition, accompanying obstetric complications and gestational age. Cesarean delivery should be performed for obstetric indications. Breast feeding should be encouraged as long as necessary precautions for viral transmission are taken. In conclusion, an individualized approach should be provided by a multidisciplinary team for the management of pregnant women with COVID-19 to achieve favorable outcomes.Key words: COVID-19, obstetric complications, pregnancy, SARS-CoV-2, vaccines

🔖

Cite This Article

ŞAHİN, D., WEBSTER, S. N., TEKİN, Ö. M., TANAÇAN, A. (2022). Pregnancy and COVID-19: prevention, vaccination, therapy, and beyond. Turkish Journal of Medical Sciences, Cilt: 51 - Sayı: Özel Sayı 1, 3312–3326. https://ajindex.com/articles/609369

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Pollard CA, Morran MP, Nestor-Kalinoski AL. The COVID-19 pandemic: a global health crisis. Physiological Genomics. 2020
  2. 52(11):549-557.https://doi.org/10.1152/ physiolgenomics.00089.2020 2. Hellewell J, Abbott S, Gimma A, Bosse NI, Jarvis CI et al. Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts. The Lancet Global Health. 2020
  3. 8(4):e488-e496. https://doi.org/10.1016/S2214- 109X(20)30074-7 3. Lancet T. COVID-19: protecting health-care workers. Lancet. 2020
  4. 395(10228):922. https://doi.org/10.1016/S0140- 6736(20)30644-9 4. Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know. American journal of obstetrics and gynecology. 2020
  5. 222(5):415-426. https://doi.org/10.1016/j. ajog.2020.02.017 5. Yang Z, Wang M, Zhu Z, Liu Y. Coronavirus disease 2019 (COVID-19) and pregnancy: a systematic review. The Journal of Maternal-Fetal & Neonatal Medicine. 2020:1-4. https://doi. org/10.1080/14767058.2020.1759541 6. Platto S, Wang Y, Zhou J, Carafoli E. History of the COVID-19 pandemic: origin, explosion, worldwide spreading. Biochemical and biophysical research communications. 2021
  6. https://doi.org/10.1016/j.bbrc.2020.10.087 7. Shang J, Ye G, Shi K, Wan Y, Luo C et al. Structural basis of receptor recognition by SARS-CoV-2. Nature. 2020
  7. 581(7807):221-224. https://doi.org/10.1038/s41586-020- 2179-y 8. Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell. 2020
  8. 181(2):271-280.e278. https://doi. org/10.1016/j.cell.2020.02.052 9. Wang P, Nair MS, Liu L, Iketani S, Luo Y et al. Antibody resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7. Nature. 2021:1-6. https://doi.org/10.1038/s41586-021-03398-2 10. Fontanet A, Autran B, Lina B, Kieny MP, Karim SSA et al. SARS-CoV-2 variants and ending the COVID-19 pandemic. The Lancet. 2021
  9. 397(10278):952-954. https://doi.org/10.1016/ S0140-6736(21)00370-6 11. Meyerowitz EA, Richterman A, Gandhi RT, Sax PE. Transmission of SARS-CoV-2: A Review of Viral, Host, and Environmental Factors. Annals of Internal Medicine. 2021
  10. 174(1):69-79. https://doi.org/10.7326/M20-5008 12. Prather KA, Wang CC, Schooley RT. Reducing transmission of SARS-CoV-2. Science. 2020
  11. 368(6498):1422-1424. DOI: 10.1126/ science.abc6197 13. Cheng HY, Jian SW, Liu DP, Ng TC, Huang WT et al. Contact Tracing Assessment