Journals / Turkish Journal of Medical Sciences / 2022 / Cilt: 52 - Sayı: 1

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Pages
188–194
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We may prefer not to immediately investigate the laboratory abnormalities and follow up patients with some treatments in the hair loss group.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: Vitamins and minerals are thought to play an essential but not entirely clear role in developing, preventing, and treating nonscarring alopecia.
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Key Findings & Data:Materials and methods: A total of 467 patients (287 females, 180 males) were included retrospectively: One hundred and sixty patients in the telogen effluvium group, 101 patients in the androgenetic alopecia group, 99 patients in the alopecia areata group, and 107 patients in the hair loss group (patients who could not be diagnosed with any nonscarring alopecia and wanted to have an analysis due to the complaint of hair loss).
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Conclusion & Impact:We may prefer not to immediately investigate the laboratory abnormalities and follow up patients with some treatments in the hair loss group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: Vitamins and minerals are thought to play an essential but not entirely clear role in developing, preventing, and treating nonscarring alopecia. Telogen effluvium, androgenetic alopecia, and alopecia areata are the most common forms of nonscarring alopecias. We would like to present a different perspective on laboratory abnormalities in patients with nonscarring alopecia. Materials and methods: A total of 467 patients (287 females, 180 males) were included retrospectively: One hundred and sixty patients in the telogen effluvium group, 101 patients in the androgenetic alopecia group, 99 patients in the alopecia areata group, and 107 patients in the hair loss group (patients who could not be diagnosed with any nonscarring alopecia and wanted to have an analysis due to the complaint of hair loss). Sociodemographic data, diagnostic distribution, and laboratory findings (hemoglobin, ferritin, vitamin B12, vitamin D, and TSH) were evaluated and compared. Results: The most common diagnosis was telogen effluvium in females and androgenetic alopecia in males. In women, hemoglobin (12.2% vs. 1.1%) and ferritin deficiencies (22.3% vs. 8.9%) were significantly higher than in men (p < 0.001, p < 0.001) Ferritin, hemoglobin, and vitamin B12 levels were significantly lower, and the number of patients with vitamin D, ferritin, hemoglobin and vitamin B12 deficiencies were significantly higher in the telogen effluvium group compared to the other groups. Laboratory abnormalities were detected least in the hair loss group. Conclusion: The number of patients with the highest abnormalities in all parameters was observed in the telogen effluvium group and females; therefore, we mainly suggest examining female patients with telogen effluvium first. We may prefer not to immediately investigate the laboratory abnormalities and follow up patients with some treatments in the hair loss group.

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Cite This Article

AKDENİZ, N., ÖNER, Ü. (2022). Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?. Turkish Journal of Medical Sciences, Cilt: 52 - Sayı: 1, 188–194. https://ajindex.com/articles/609253

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References (14)

  1. Almohanna HM, Ahmad AA, Tsatalis JP, Tosti A. The role of vitamins and minerals in hair loss: A review. Dermatologic Therapy 2019
  2. 9 (1): 51-70. doi: 10.1007/s13555-018-0278-6 2. Aktaş H, Ertuğrul G. Hair loss: who needs laboratory investigations? Kocatepe Medical Journal 2020
  3. doi: 10.18229/kocatepetip.536112 3. Rasheed H, Mahgoub D, Hegazy R, El-Komy M, Abdel Hay R et al. Serum ferritin and vitamin D in female hair loss: Do they play a role? Skin Pharmacology and Physiology 2013
  4. 26 (2): 101-107. doi: 10.1159/000346698 4. Sinclair R: There is no clear association between low serum ferritin and chronic diffuse telogen hair loss. British Journal of Dermatology 2002
  5. doi: 10.1046/j.1365- 2133.2002.04997.x 5. Gönül M, Gul Ü, Pişkin E, Çakmak SK, Soylu S et al. Retrospective evaluation of alopecia areata patients. Turkish Journal of Dermatology 2011
  6. doi: 10.5152/tdd.2011.10 6. Rushton DH. Nutritional factors and hair loss. Clinical and Experimental Dermatology 2002
  7. 27 (5): 396-404. doi: 10.1046/j.1365-2230.2002.01076.x 7. Sokmen F. The etiological role of thyroid dysfunction and vitamin deficiency in patients with telogen effluvium. Osmangazi Journal of Medicine 2020
  8. 42 (6): 705-709. doi: 10.20515/ otd.775603 8. Inui S. Trichoscopy for common hair loss diseases: Algorithmic method for diagnosis. Journal of Dermatology 2011
  9. 38 (1): 71- 75. doi: 10.1111/j.1346-8138.2010.01119.x 9. Vegesna V, O’Kelly J, Uskokovic, M, Said J, Lemp N et al. Vitamin D3 analogs stimulate hair growth in nude mice. Endocrinology 2002
  10. doi: 10.1210/en.2002-220118 10. Unal M, Gonulalan G. Serum vitamin D level is related to disease severity in pediatric alopecia areata. Journal of Cosmetic Dermatology 2018
  11. 17(1):101-104. doi: 10.1111/jocd.12352 11. Oğrum A, Boyraz N, Toğral AK, Karasatı S, Ekşioğlu HM. Evaluation of 25 hydroxy vitamin D3 levels in patients with alopecia areata. Turkish Archives of Dermatology and Venereology 2015
  12. doi: 10.4274/turkderm.07888 12. Karadağ AS, Ertuğrul DT, Tutal E, Akin KO. The role of anemia and vitamin D levels in acute and chronic telogen effluvium. Turkish Journal of Medical Science 2011
  13. 41 (5): 827-833. doi:10.3906/sag-1005-853 13. Stephanie AP, Vercellotti GM, Donovan JC, Hordinsky MK. Iron deficiency and diffuse nonscarring scalp alopecia. Journal of the American Academy of Dermatology 2010
  14. 63 (6): 1070- 1076. doi: 10.1016/j.jaad.2009.05.054 14. Kantor J, Kessler LJ, Brooks DG, C