Journals / Turkish Journal of Medical Sciences / 2022 / Cilt: 52 - Sayı: 1

Evaluation of clinical and laboratory findings in severe group COVID-19 pregnants without comorbidity

Pages
11–20
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Also, the need for intensive care, the rate of delivery by caesarean section, and the rate of preterm delivery of these pregnant women were also found to be high.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: COVID - 19 disease may be seen with different clinical presentations in pregnant women.
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Key Findings & Data:In this study, we aimed to evaluate the clinical and laboratory findings in pregnant women with COVID - 19 who had no comorbid disease.
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Conclusion & Impact:Also, the need for intensive care, the rate of delivery by caesarean section, and the rate of preterm delivery of these pregnant women were also found to be high.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: COVID - 19 disease may be seen with different clinical presentations in pregnant women. Comorbid diseases are important factors affecting the progression of this disease. In this study, we aimed to evaluate the clinical and laboratory findings in pregnant women with COVID - 19 who had no comorbid disease. Material and methods: This retrospective designed study included 217 patients with Covid PCR positive in typically COVID - 19 clinic. The patients were classified into asymptomatic, nonsevere, and severe disease groups. The symptoms, laboratory results, hospital followups and intensive care records of the patients and the findings of new borns are presented. Results: Most of the patients (78%) were in the third trimester of pregnancy, and 103 patients in the study group had severe disease. Fever in the non-severe group and respiratory distress in the severe group were the most common symptoms in the patients. The severe clinical manifestations were specifically observed in the third trimester patients. In the severe group, neutrophil, lactat dehydrogenase, ferritin, CK - MB, IL – 6, and hospital stay were statistically higher than those in other groups (p < 0.05). Increase in BUN and creatine were the most predictive parameters in intensive care admission. While the intensive care unit (ICU) requirement was higher in patients in the severe group, premature birth was observed more frequently in the severe group (p < 0.05). Conclusion: COVID - 19 positive pregnant women were mostly detected in the third trimester, and the disease was more severe in this period. Also, the need for intensive care, the rate of delivery by caesarean section, and the rate of preterm delivery of these pregnant women were also found to be high.

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Cite This Article

BEKÇİBAŞI, M., ASENA, M., BAĞLI, İ., BOZKURT, F., COŞKUN, Ö., YELEÇ, S. (2022). Evaluation of clinical and laboratory findings in severe group COVID-19 pregnants without comorbidity. Turkish Journal of Medical Sciences, Cilt: 52 - Sayı: 1, 11–20. https://ajindex.com/articles/609236

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References (11)

  1. Breslin N, Baptiste C, Gyamfi- Bannerman C, Miller R, Martinez R et al. Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals. American Journal of Obstetrics & Gynecology MFM 2020
  2. 2 (2): 100118. doi: 10.1016/j.ajogmf.2020.100118 2. Berkowitz K, LaSala A. Risk factors associated with the increasing prevalence of pneumonia during pregnancy. American Journal of Obstetrics and Gynecology 1990
  3. 163 (3): 981-985. doi: 10.1016/0002-9378(90)91109-p 3. Magro C, Mulvey JJ, Berlin D, Nuovo G, Salvatore S et al. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID- 19 infection: a report of five cases. Translational Research 2020
  4. doi: 10.1016/j.trsl.2020.04.007 4. Jamieson DJ, Theiler RN, Rasmussen SA. Emerging infections and pregnancy. Emerging Infectious Diseases 2006
  5. 12 (11): 1638-1643. doi: 10.3201/eid1211.060152 5. Gardner MO, Doyle NM. Asthma in pregnancy. Obstetrics and Gynecology Clinics of North America 2004
  6. 31 (2): 385-413. doi: 10.1016/j.ogc.2004.03.010 6. Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. American Jounal of Obstetrics and Gynecology 2020
  7. 222 (6): 521-531. doi: 10.1016/j.ajog.2020.03.021 7. Pierce- Williams RAM, Burd J, Felder L, Khoury R, Bernstein PS et al. Clinical course of severe and critical coronavirus disease 2019 in hospitalized pregnancies: a United States cohort study. American of Journal Obstetrics & Gynecology MFM 2020
  8. 2 (3): 100134. doi: 10.1016/j.ajogmf.2020.100134 8. Wu X, Sun R, Chen J, Xie Y, Zhang S et al. Radiological findings and clinical characteristics of pregnant women with COVID- 19 pneumonia. International Journal of Gynecology & Obstetrics 2020
  9. 150 (1): 58-63. doi: 10.1002/ijgo.13165 9. Gülsen A. Simple classification of COVID- 19 patients. Journal of Lung, Pulmonary & Respiratory Research 2020
  10. 7 (3): 62-63. doi: 10.15406/jlprr:2020.07.00230 10. Yan J, Guo J, Fan C, Juan J, Yu X et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. American Journal of Obstetrircs and Gynecology 2020
  11. 223 (1): 111.e1- 111.e14. doi: 10.1016/j.ajog.2020.04.014 11. Delahoy MJ, Whitaker M, O’Halloran A, Chai SJ, Kirley PD et al. Characteristics and Maternal and Birth Outcomes of Hospitalized Pregnant Women with Laboratory-Confirmed COVID- 19- COVID- NET, 13 States, March