Journals / Turkish Journal of Medical Sciences / 2022 / Cilt: 52 - Sayı: 3

Effectiveness of a supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with anti-TNF therapy in anti-TNF-naive patients with active ankylosing spondylitis

Pages
667–676
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

At the end of the 12 weeks, the results showed that there were additional improvements in all outcome measurement parameters in the SG compared to the CG.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: This study aimed to investigate the effectiveness of a supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with antitumor necrosis factor (TNF) therapy in anti-TNF-naive patients with active ankylosing spondylitis (AS).
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Key Findings & Data:Materials and methods: Forty-eight patients were divided into two groups: the control group (CG; n = 36) received only anti-TNF therapy, and the study group (SG; n = 12) received the supervised exercise therapy based on the biopsychosocial model in addition to anti-TNF therapy.
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Conclusion & Impact:At the end of the 12 weeks, the results showed that there were additional improvements in all outcome measurement parameters in the SG compared to the CG.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: This study aimed to investigate the effectiveness of a supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with antitumor necrosis factor (TNF) therapy in anti-TNF-naive patients with active ankylosing spondylitis (AS). Materials and methods: Forty-eight patients were divided into two groups: the control group (CG; n = 36) received only anti-TNF therapy, and the study group (SG; n = 12) received the supervised exercise therapy based on the biopsychosocial model in addition to anti-TNF therapy. The measurements of disease activity and functionality were evaluated by The Bath AS Disease Activity Index (BASDAI) and The Bath AS Functional Index (BASFI) respectively. Other outcome measures evaluated biopsychosocial status, emotional state, spinal mobility, pain, fatigue, sleep, and quality of life. All measurements were applied to both groups at baseline and repeated 12 weeks later. Results: BASDAI and BASFI analyses revealed significant differences between groups in favor of the SG (p < 0.05). At the end of the 12 weeks, the results showed that there were additional improvements in all outcome measurement parameters in the SG compared to the CG. Conclusion: The supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with anti-TNF therapy is more effective than only anti-TNF therapy in anti-TNF-naive patients with active AS.

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Cite This Article

KARAKAYA, J., ÜNAL, E., KARACA, N. B., KALYONCU, U., KİRAZ, S. (2022). Effectiveness of a supervised group exercise therapy based on the biopsychosocial model introduced simultaneously with anti-TNF therapy in anti-TNF-naive patients with active ankylosing spondylitis. Turkish Journal of Medical Sciences, Cilt: 52 - Sayı: 3, 667–676. https://ajindex.com/articles/609211

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References (12)

  1. Braun J, Sieper J. Ankylosing spondylitis. The Lancet 2007
  2. 369 (9570): 1379-1390. doi: 10.1016/s0140-6736(07)60635-7 2. Pahwa D, Chhabra A, Arora MK. Anaesthetic management of patients with ankylosing spondylitis. Trends in Anaesthesia and Critical Care 2013
  3. 3 (1): 19-24. doi: 10.1016/j.tacc.2012.11.001 3. Kotsis K, Voulgari PV, Drosos AA, Carvalho AF, Hyphantis T. Health-related quality of life in patients with ankylosing spondylitis: a comprehensive review. Expert Review of Pharmacoeconomics & Outcomes Research 2014
  4. 14 (6): 857- 872. doi: 10.1586/14737167.2014.957679 4. Özdemir O. Quality of life in patients with ankylosing spondylitis: relationships with spinal mobility, disease activity and functional status. Rheumatology International 2011
  5. 31 (5): 605-610. doi: 10.1007/s00296-009-1328-2 5. Martindale J, Shukla R, Goodacre J. The impact of ankylosing spondylitis/axial spondyloarthritis on work productivity. Best Practice & Research Clinical Rheumatology 2015
  6. 29 (3): 512- 523. doi: 10.1016/j.berh.2015.04.002 6. Günaydin R, Karatepe AG, Çeşmeli N, Kaya T. Fatigue in patients with ankylosing spondylitis: relationships with disease-specific variables, depression, and sleep disturbance. Clinical Rheumatology 2009
  7. 28 (9): 1045-1051. doi: 10.1007/ s10067-009-1204-1 7. Brophy S, Davies H, Dennis MS, Cooksey R, Husain MJ et al. Fatigue in ankylosing spondylitis: treatment should focus on pain management. Seminars in Arthritis and Rheumatism 2013
  8. 42 (4): 361-367. doi: 10.1016/j.semarthrit.2012.06.002 8. Aydin E, Bayraktar K, Turan Y, Omurlu I, Tasbatan E et al. Sleep quality in patients with ankylosing spondylitis. Revista Brasileira de Reumatologia 2015
  9. doi: 10.1016/j. rbre.2014.12.007 9. Ertenli I, Ozer S, Kiraz S, Apras SB, Akdogan A et al. Infliximab, a TNF-alpha antagonist treatment in patients with ankylosing spondylitis: the impact on depression, anxiety and quality of life level. Rheumatology International 2012
  10. 32 (2): 323-330. doi: 10.1007/s00296-010-1616-x 10. Gatchel RJ, Kishino ND. The Biopsychosocial Approach to Pain Management 2008 11. Booth J, Moseley GL, Schiltenwolf M, Cashin A, Davies M et al. Exercise for chronic musculoskeletal pain: A biopsychosocial approach. Musculoskeletal Care 2017
  11. 15 (4): 413-421. doi: 10.1002/msc.1191 12. Sari I, Ozturk MA, Akkoc N. Treatment of ankylosing spondylitis. Turkish Journal of Medical Sciences 2015
  12. 45 (2): 416-430. doi: 10.3906/sag-1401-79 13. Braun J, van der Berg R, Baraliakos X,