Journals / Turkish journal of emergency medicine (Online) / 2019 / Cilt: 19 - Sayı: 1

Can inhaled heroin be a cause of bilateral globus pallidus ischemic injury?

Pages
39–41
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We, therefore, advocate that inhaled heroin should be considered as one of the causes of bilateral globus pallidus lesions, in addition to IV heroin and cocaine and physicians should be aware of the possibility of alternate forms of heroin abuse in such patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Bilateral globus pallidus lesions have been characteristically thought to be associated with global cerebral hypoperfusion and hypoxic changes.
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Key Findings & Data:Case presentation: We present a case of a 50-year-old male who came to the hospital after being found down for 3 hours.
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Conclusion & Impact:Conclusion: We, therefore, advocate that inhaled heroin should be considered as one of the causes of bilateral globus pallidus lesions, in addition to IV heroin and cocaine and physicians should be aware of the possibility of alternate forms of heroin abuse in such patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Bilateral globus pallidus lesions have been characteristically thought to be associated with global cerebral hypoperfusion and hypoxic changes. One of the important causative factors that need to be considered is the opiate drug abuse. Case presentation: We present a case of a 50-year-old male who came to the hospital after being found down for 3 hours. He was found to have weakness of right upper and lower extremity. MRI showed bilateral globus pallidus infarcts. He later admitted to inhalation of heroin. Over the next few days, weakness started to improve and he was eventually discharged to rehabilitation. This case is a unique presentation of bilateral globus pallidus lesions after a one-time inhalation of heroin. Conclusion: We, therefore, advocate that inhaled heroin should be considered as one of the causes of bilateral globus pallidus lesions, in addition to IV heroin and cocaine and physicians should be aware of the possibility of alternate forms of heroin abuse in such patients.

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Cite This Article

ULLAH, W., IQBAL, I., KHAN, M. A. A. (2022). Can inhaled heroin be a cause of bilateral globus pallidus ischemic injury?. Turkish journal of emergency medicine (Online), Cilt: 19 - Sayı: 1, 39–41. https://ajindex.com/articles/605298

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References (14)

  1. Alquist CR, McGoey R, Bastian F, Newman W. Bilateral globus pallidus lesions. J La State Med Soc. 2012 May;164(3):145–146
  2. Niehaus L, Röricht S, Meyer BU, Sander B. Nuclear magnetic resonance tomography detection of heroin-associated CNS lesions. Aktuelle Radiol. 1997 Nov;7(6):309–311
  3. Büttner A, Mall G, Penning R, Weis S. The neuropathology of heroin abuse. Forensic Sci Int. 2000 Sep 11;113(1-3):435–442
  4. Zuckerman GB, Ruiz DC, Keller IA, Brooks J. Neurologic complications following intranasal administration of heroin in an adolescent. Ann Pharmacother. 1996 Jul;30(7-8):778–781
  5. Richter RW, Baden MM. Neurological complications of heroin addiction. Trans Am Neurol Assoc. 1969;94:330–332
  6. Schein P, Yessayan L, Mayman C. Acute transverse myelitis associated with intravenous opium. Neurology. 1971;21:101–102
  7. Brust J, Richter R. Stroke associated with addiction to heroin. J Neurol. 1976;39:194–199
  8. Kadi R, Rumy A, Stadnik T, Cannie M, Abiglia C, Davano L. Bilateral lesions of the globus pallidus in a young woman. JBR-BTR. 2014 Mar 1;97(2):118–120
  9. Vila N, Chamorro A. Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases. Clin Neurol Neurosurg. 1997 Dec 1;99(4):259–262
  10. Andersen SN, Skullerud K. Hypoxic/ischaemic brain damage, especially pallidal lesions, in heroin addicts. Forensic Sci Int. 1999 May 31;102(1):51–59
  11. Hantson P, Duprez T. Imagerie cérébrale et intoxications. Reanimation. 2009 Oct 1;18(7):598–605
  12. De Roock S, Hantson P, Laterre PF, Duprez T. Extensive pallidal and white matter injury following a cocaine overdose. Intensive Care Med. 2007 Nov 1;33(11):2030–2031
  13. Hosztafi S. Heroin addiction. Acta Pharm Hung. 2011;81(4):173–183
  14. Cone EJ, Holicky BA, Grant TM, Darwin WD, Goldberger BA. Pharmacokinetics and pharmacodynamics of intranasal “snorted” heroin. J Anal Toxicol. 1993 Oct 1;17(6):327–337.