Journals / Turkish Journal of Chemistry / 2000 / Cilt: 24 - Sayı: 4

Ion-Selective Membrane Electrode for the Determination of a Novel Phenylpiperazine Antidepressant, Nefazodone

Pages
353–360
Publication Date
2022-11-04
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The potentiometric standard addition method and the argentometric titration method are used to determine the NFN amount in pure solution.

📌 3 Key Takeaways

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Objective & Hypothesis:The construction and performance characteristics of ion-selective membrane electrodes for a newly found phenylpiperazine antidepressant, Nefazodone (NFN), based on its ion-pair complexes with phosphotungstate (PT), tetraphenylborate (TPB), tungstosilicate (TS) and reineckate (RN) in a poly(vinyl chloride) (PVC) matrix are described.
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Key Findings & Data:This electrode exhibits a Nernstian response (62.6 ± 0.4 mV per decade) in the range 1.5 x 10-5 to 1.0 x 10-2 M NFN.HCl in solutions.
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Conclusion & Impact:The potentiometric standard addition method and the argentometric titration method are used to determine the NFN amount in pure solution.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Turk. J. Chem. · (2000) · 353-360. Full text: pdf Other articles published in the same issue: Turk. J. Chem.

Abstract

The construction and performance characteristics of ion-selective membrane electrodes for a newly found phenylpiperazine antidepressant, Nefazodone (NFN), based on its ion-pair complexes with phosphotungstate (PT), tetraphenylborate (TPB), tungstosilicate (TS) and reineckate (RN) in a poly(vinyl chloride) (PVC) matrix are described. The best ion-selective electrode for determination of NFN contains NFN-PT as the active material. This electrode exhibits a Nernstian response (62.6 ± 0.4 mV per decade) in the range 1.5 x 10-5 to 1.0 x 10-2 M NFN.HCl in solutions. The selectivity of this electrode to NFN in the presence of a number of sugar molecules, cations and drugs is reported. The potentiometric standard addition method and the argentometric titration method are used to determine the NFN amount in pure solution.

Özet

The construction and performance characteristics of ion-selective membrane electrodes for a newly found phenylpiperazine antidepressant, Nefazodone (NFN), based on its ion-pair complexes with phosphotungstate (PT), tetraphenylborate (TPB), tungstosilicate (TS) and reineckate (RN) in a poly(vinyl chloride) (PVC) matrix are described. The best ion-selective electrode for determination of NFN contains NFN-PT as the active material. This electrode exhibits a Nernstian response (62.6 ± 0.4 mV per decade) in the range 1.5 x 10-5 to 1.0 x 10-2 M NFN.HCl in solutions. The selectivity of this electrode to NFN in the presence of a number of sugar molecules, cations and drugs is reported. The potentiometric standard addition method and the argentometric titration method are used to determine the NFN amount in pure solution.

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Cite This Article

ERDEM, A., KERMAN, K., ÖZKAN, D., MERİÇ, B., DALBASTI, T., ÖZSÖZ, M. (2022). Ion-Selective Membrane Electrode for the Determination of a Novel Phenylpiperazine Antidepressant, Nefazodone. Turkish Journal of Chemistry, Cilt: 24 - Sayı: 4, 353–360. https://ajindex.com/articles/602442

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