Journals / Turkish Journal of Chemistry / 2001 / Cilt: 25 - Sayı: 4

Spectrophotometric Determination of Propranolol as Cu(II), Ni(II) and Co(II) Dithiocarbamate Complexes

Pages
485–490
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no significant difference between the mean values and the precisions of the two methods at the 95% confidence level.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A spectrophotometric method was developed for the determination of the beta adrenergic blocking drug propranolol.
📊
Key Findings & Data:The method was based on the formation of Cu(II), Ni(II) and Co(II)-dithiocarbamate complexes from the secondary amine group of propranolol with carbondisulfide (CS2) and the acetate salts of the metals in ammonia medium.
💡
Conclusion & Impact:There was no significant difference between the mean values and the precisions of the two methods at the 95% confidence level.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Propranolol · pharmaceutical Formulations · spectrophptpmetry

Abstract

A spectrophotometric method was developed for the determination of the beta adrenergic blocking drug propranolol. The method was based on the formation of Cu(II), Ni(II) and Co(II)-dithiocarbamate complexes from the secondary amine group of propranolol with carbondisulfide (CS2) and the acetate salts of the metals in ammonia medium. The method was applied to the analysis of propranolol tablets and the results were statistically compared with those obtained by the official method using t- and F-tests. There was no significant difference between the mean values and the precisions of the two methods at the 95% confidence level.

Özet

A spectrophotometric method was developed for the determination of the beta adrenergic blocking drug propranolol. The method was based on the formation of Cu(II), Ni(II) and Co(II)-dithiocarbamate complexes from the secondary amine group of propranolol with carbondisulfide (CS2) and the acetate salts of the metals in ammonia medium. The method was applied to the analysis of propranolol tablets and the results were statistically compared with those obtained by the official method using t- and F-tests. There was no significant difference between the mean values and the precisions of the two methods at the 95% confidence level.

🔖

Cite This Article

GÖLCÜ, A., SERİN, S., DOLAZ, M. (2022). Spectrophotometric Determination of Propranolol as Cu(II), Ni(II) and Co(II) Dithiocarbamate Complexes. Turkish Journal of Chemistry, Cilt: 25 - Sayı: 4, 485–490. https://ajindex.com/articles/602410

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...