Journals / Turkish Journal of Chemistry / 2015 / Cilt: 39 - Sayı: 4

Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-a]pyridine derivatives

Pages
867–873
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This method provides several advantages such as high yields, facile work-up, and environmental friendliness.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A series of novel 1,2,4-triazolo[4,3-a]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by 1 H NMR, MS, and elemental analysis.
📊
Key Findings & Data:A series of novel 1,2,4-triazolo[4,3-a]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by 1 H NMR, MS, and elemental analysis.
💡
Conclusion & Impact:This method provides several advantages such as high yields, facile work-up, and environmental friendliness.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A series of novel 1,2,4-triazolo[4,3-a]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by 1 H NMR, MS, and elemental analysis. This method provides several advantages such as high yields, facile work-up, and environmental friendliness.

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Cite This Article

YANG, M., ZHANG, L., SUN, Z., LIU, X., WENG, J., TAN, C., HU, B. (2022). Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-a]pyridine derivatives. Turkish Journal of Chemistry, Cilt: 39 - Sayı: 4, 867–873. https://ajindex.com/articles/602076

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References (25)

  1. Sun, N. B.; Liu, X. H.; Weng, J. Q.; Tan, C. X. J. Chem. Soc. Pak. 2013, 35, 499–502
  2. Weng, J. Q.; Wang, L.; Liu, X. H. J. Chem. Soc. Pak. 2012, 34, 1248–1252
  3. Liu, X. H.; Pan, L.; Weng, J. Q.; Tan, C. X.; Li, Y. H.; Wang, B. L.; Li, Z. M. Mol. Divers. 2012, 16, 251–260
  4. Liu, X. H.; Xu, X. Y.; Tan, C. X.; Weng, J. Q.; Xin, J. H.; Chen, J. Pest Manag. Sci. 2015, 71, 292–301
  5. Liu, X. H.; Weng, J. Q.; Tan, C. X. J. Chem. 2013, 2013, 306361
  6. Liu, X. H.; Sun, Z. H.; Yang, M. Y.; Tan, C. X.; Weng, J. Q.; Zhang, Y. G.; Ma, Y. Chem. Biol. Drug Des. 2014, 84, 342–347
  7. G¨ulk¨ok, Y.; Bi¸cer, T.; Onurda˘g, F. K.; Ozgen, S.; S¸ahin, M. F.; Do˘gruer, D. S. ¨ Turk. J. Chem. 2012, 36, 279–291
  8. Zhang, Y. Y.; Yang, W. Q.; Xu, K. P.; Ma, M. L.; Wang, Y. L. Lett. Drug Des. Discov. 2013, 10, 219–225
  9. Wujec, M.; K¸edzierska, E.; Ku´smierz, E.; Plech, T.; Wr´obel, A.; Paneth, A.; Orzelska, J.; Fidecka, S.; Paneth, P. Molecules 2014, 19, 4745–4759
  10. Prashanth, M. K.; Revanasiddappa, H. D. Lett. Drug Des. Discov. 2014, 11, 712–720
  11. Esteves-Souza, A.; Rodrigues-Santos, C. E.; Del Cistia, C. N.; Silva, D. R.; Sant’Anna, C. M. R.; Echevarria, A. Molecules 2012, 17, 12882–12894
  12. Kocyigit-Kaymakcioglu, B.; Celen, A. O.; Tabanca, N.; Ali, A.; Khan, S. I.; Khan, I. A.; Wedge, D. E. Molecules 2013, 18, 3562–3576
  13. Tang, X.; Xue, F.; Ma, H. J.; Cao, X. F.; Chen, C. S.; Li, X. G. Res. Chem. Intermed. 2013, 39, 805–820
  14. Zhang, X. Y.; Li, Y. S.; Weng, J. Q.; Tan, C. X. Chin. J. Org. Chem. 2011, 31, 1295–1299
  15. Guo, D. S. Chin. J. Org. Chem. 2004, 24, 1118–1121
  16. Zhou, H. Y.; Gong, R. J.; Miao, W. R.; Qu, J. P. Fine Chem. 2013, 30, 475–478
  17. Sahoo, B. M.; Dinda, S. C.; Kumar, B. V. V. R.; Panda, J.; Brahmkshatriya, P. S. Lett. Drug Des. Discov. 2014, 11, 82–89
  18. Shen, S. D.; Khang, P. V.; Chen, Y. J.; Lei, M.; Hu, L. H. ARKIVOC 2013, 3, 413–423
  19. Munshi, P.; Bhaduri, S. Curr. Sci. 2009, 97, 63–72
  20. Parvanak Boroujen, K.; Shojaei, P. Turk. J. Chem. 2013, 37, 756–764
  21. Du, X. J.; Wang, Z. P.; Hou, Y. L.; Zhang, C.; Li, Z. M.; Zhao, W. G. Tetrahedron Lett. 2014, 55, 1002–1005
  22. Cui, C.; Zhu, C.; Du, X. J.; Wang, Z. P.; Li, Z. M.; Zhao, W. G. Green Chem. 2012, 14, 3157–3163
  23. Kahveci, B.; Karaali, N.; Yılmaz, F.; Mente¸se, E. Turk. J. Chem. 2014, 38, 423–429
  24. Zhang, L. J.; Yang, M. Y.; Sun, Z. H.; Tan, C. X.; Weng, J. Q.; Wu, H. K.; Liu, X. H. Lett. Drug Des. Discov. 2014, 11, 1107–1111
  25. Yan, S. L.; Yang, M. Y.; Sun, Z