Journals / Turkish Journal of Chemistry / 2018 / Cilt: 42 - Sayı: 6

Quantification of flavonoids isolated from Mentha spicata in selected clones of Turkish mint landraces

Pages
1695–1705
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Consisting of pharmaceutically valuable compounds,M. spicata and cultivated Turkish mint landraces could be a source of 5-demethyl sinensetin (1), hesperidin (2), didymin(3), and linarin (4).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Mint has been used extensively in traditional medicines, spices, and herbal teas throughout the world.Isolation of flavonoids from Mentha spicata and quantification of these compounds in selected clones of Turkish mintslandraces were achieved.
📊
Key Findings & Data:The solvent was removed under reduced pressure to yield the extract, subjected tosilica gel column chromatography to isolate 5-demethyl sinensetin (1), hesperidin (2), didymin (3), and linarin (4), thestructures of which were elucidated by 1D NMR, 2D NMR, and LC-TOF/MS.
💡
Conclusion & Impact:Consisting of pharmaceutically valuable compounds,M. spicata and cultivated Turkish mint landraces could be a source of 5-demethyl sinensetin (1), hesperidin (2), didymin(3), and linarin (4).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Mint has been used extensively in traditional medicines, spices, and herbal teas throughout the world.Isolation of flavonoids from Mentha spicata and quantification of these compounds in selected clones of Turkish mintslandraces were achieved. M. spicata was dried in shade and then boiled in water. After filtration, the aqueous extractwas partitioned with ethyl acetate. The solvent was removed under reduced pressure to yield the extract, subjected tosilica gel column chromatography to isolate 5-demethyl sinensetin (1), hesperidin (2), didymin (3), and linarin (4), thestructures of which were elucidated by 1D NMR, 2D NMR, and LC-TOF/MS. The isolated compounds were employedas standard flavonoids to determine the quantitative variations in cultivated Turkish mint landraces belonging to Mentha× piperita L., M. spicata L., and M. × villosonervata Opiz by HPLC. The quantities of hesperidin (2), didymin (3), andlinarin (4) in M. spicata were found as 11.83, 3.85, and 42.21 mg/g dried plant weight (DW), respectively, while that of5-demethyl sinensetin (1) in M. villosonervata was 2.9 mg/g DW. Consisting of pharmaceutically valuable compounds,M. spicata and cultivated Turkish mint landraces could be a source of 5-demethyl sinensetin (1), hesperidin (2), didymin(3), and linarin (4).

🔖

Cite This Article

ELMASTAŞ, M., TELCİ, İ., AKSİT, H., ERENLER, R., GÜL, F., KAYIR, Ö., TÜFEKÇİ, A. R., DEMİRTAŞ, İ. (2022). Quantification of flavonoids isolated from Mentha spicata in selected clones of Turkish mint landraces. Turkish Journal of Chemistry, Cilt: 42 - Sayı: 6, 1695–1705. https://ajindex.com/articles/602023

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (24)

  1. Newman, D. J.; Cragg, G. M. J. Nat. Prod. 2007, 70, 461-477
  2. Erenler, R.; Sen, O.; Yaglioglu, A. S.; Demirtas, I. Comb. Chem. High Throughput Screen. 2016, 19, 66-72
  3. Erenler, R.; Sen, O.; Yildiz, I.; Aydin, A. Rec. Nat. Prod. 2016, 10, 766-770
  4. Erenler, R.; Yilmaz, S.; Aksit, H.; Sen, O.; Genc, N.; Elmastas, M.; Demirtas, I. Rec. Nat. Prod. 2014, 8, 32-36
  5. Topcu, G.; Erenler, R.; Cakmak, O.; Johansson, C. B.; Celik, C.; Chai, H. B.; Pezzuto, J. M. Phytochemistry 1999, 50, 1195-1199
  6. Karan, T.; Erenler, R. Pharmacogn. Mag. 2017, 13, 723-725
  7. Karan, T.; Yildiz, I.; Aydin, A.; Erenler, R. Rec. Nat. Prod. 2018, 12, 273-283
  8. Tucker, A. O.; Naczi, R. F. In Mint: The Genus Mentha; Lawrence, B. M., Ed. Taylor & Francis: London, UK, 2006, pp. 1-37
  9. Liu, W.; Lawrence, B. M. In Mint: The Genus Mentha; Lawrence, B. M., Ed. Taylor & Francis: London, UK, 2006, pp 165-184
  10. Telci, I.; Kacar, O.; Bayram, E.; Arabacı, O.; Demirtaş, İ.; Yılmaz, G.; Sönmez, Ç.; Göksu, E. Ind. Crop Prod. 2011, 34, 1193-1197
  11. Mucciarelli, M.; Camusso, W.; Bertea, C. M.; Bossi, S.; Maffei, M. Phytochemistry 2001, 57, 91-98
  12. Salin, O.; Tormakangas, L.; Leinonen, M.; Saario, E.; Hagstrom, M.; Ketola, R. A.; Saikku, P.; Vuorela, H.; Vuorela, P. M. J. Agr. Food Chem. 2011, 59, 12836-12842
  13. Demirtas, I.; Erenler, R.; Elmastas, M.; Goktasoglu, A. Food Chem. 2013, 136, 34-40
  14. Inoue, T.; Sugimoto, Y.; Masuda, H.; Kamei, C. Biol. Pharm. Bull. 2002, 25, 256-259
  15. Erenler, R.; Meral, B.; Sen, O.; Elmastas, M.; Aydin, A.; Eminagaoglu, O.; Topcu, G. Pharm. Biol. 2017, 55, 1646-1653
  16. Huang, Y. S.; Ho, S. C. Food Chem. 2010, 119, 868-873
  17. Akao, Y.; Itoh, T.; Ohguchi, K.; Iinuma, M.; Nozawa, Y. Bioorgan. Med. Chem. 2008, 16, 2803-2810
  18. Bellete, B. S.; Ramin, L. Z.; Porto, D.; Ribeiro, A. I.; Forim, M. R.; Zuin, V. G.; Fernandes, J. B.; Silva, M. J. Brazil. Chem. Soc. 2018, 29, 1123-1129
  19. Ernawita; Wahyuono, R. A.; Hesse, J.; Hipler, U. C.; Elsner, P.; Bohm, V. Antioxidants 2017, 6, 15
  20. Lam, I. K.; Alex, D.; Wang, Y. H.; Liu, P.; Liu, A. L.; Du, G. H.; Lee, S. M. Y. Mol. Nutr. Food Res. 2012, 56, 945-956
  21. Ohguchi, K.; Iinuma, M.; Nozawa, Y.; Ito, M. J. Med. Plants Res. 2014, 8, 1060-1064
  22. Wang, D.; Wang, J.; Huang, X.; Tu, Y.; Ni, K. J. Pharmaceut. Biomed. 2007, 44, 63-69
  23. Wei, G. J.; Sheen, J. F.; Lu, W. C.; Hwang, L. S.; Ho, C. T.; Lin, C. I. J. Agr. Food Chem. 2013, 61, 5016-5021
  24. Guedon, D. J.; Pasquier, B. P. J. Agric. Fo