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Journals / Turkish Journal of Chemistry / 2018 / Cilt: 42 - Sayı: 5

Tetrahydropyridine: a promising heterocycle for pharmacologically active molecules

Noor-ul-Amin MOHSIN
Matloob AHMAD
Pages
1191–1216
Publication Date
2022-11-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we summarize the recent literature dealingwith the bioactive nature of this important heterocycle.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The tetrahydropyridine (THP) ring system has received considerable focus due to its excellent ability to actas a pharmacophore.
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Key Findings & Data:It is recognized as a major constituent in natural alkaloids.
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Conclusion & Impact:In this review, we summarize the recent literature dealingwith the bioactive nature of this important heterocycle.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The tetrahydropyridine (THP) ring system has received considerable focus due to its excellent ability to actas a pharmacophore. It is recognized as a major constituent in natural alkaloids. THP derivatives have been reportedfor a diverse range of biological activities. Recent synthetic works contain syntheses of monosubstituted, disubstituted,trisubstituted, highly functionalized, and condensed structures. In this review, we summarize the recent literature dealingwith the bioactive nature of this important heterocycle.

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Cite This Article

MOHSIN, N., AHMAD, M. (2022). Tetrahydropyridine: a promising heterocycle for pharmacologically active molecules. Turkish Journal of Chemistry, Cilt: 42 - Sayı: 5, 1191–1216. https://ajindex.com/articles/601734

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