Journals / Turkish Journal of Chemistry / 2020 / Cilt: 44 - Sayı: 1

Choline derivatives immobilized on silica to catalyze transesterification reaction for production of glycerophosphocholine

Pages
249–260
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Afirst-order kinetic model was employed and the relevant parameters were calculated to investigate kinetic characteristics of transesterification.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Choline derivatives were covalently immobilized on the surface of γ -aminated silica.
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Key Findings & Data:Fourier transform infrared analysis and thermogravimetric analysis/differential thermal gravimetry indicatedthat the surface of the γ -aminated silica was covered by choline derivatives and the highest immobilization amountreached 1.1 mmol/g under optimal conditions.
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Conclusion & Impact:Afirst-order kinetic model was employed and the relevant parameters were calculated to investigate kinetic characteristics of transesterification.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Choline derivatives were covalently immobilized on the surface of γ -aminated silica. The obtained immobilized choline derivative was then successfully used for a transesterification reaction to produce glycerophosphocholine(GPC). Fourier transform infrared analysis and thermogravimetric analysis/differential thermal gravimetry indicatedthat the surface of the γ -aminated silica was covered by choline derivatives and the highest immobilization amountreached 1.1 mmol/g under optimal conditions. More importantly, the highest yield of GPC reached 97.9% duringtransesterification. With regard to GPC in food or medicine for human use, the immobilization technology can avoidcatalyst contamination of the product and increase the safety of the product. The recyclability and stability of theimmobilized choline derivative were excellent, as demonstrated by its use 20 times without any loss of productivity. Afirst-order kinetic model was employed and the relevant parameters were calculated to investigate kinetic characteristics of transesterification.

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Cite This Article

CHEN, D., ZHENG, W., WEI, L., TANG, K., LI, B., ZHAO, B., ZHANG, X. (2022). Choline derivatives immobilized on silica to catalyze transesterification reaction for production of glycerophosphocholine. Turkish Journal of Chemistry, Cilt: 44 - Sayı: 1, 249–260. https://ajindex.com/articles/601523

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