Journals / The European Research Journal / 2022 / Cilt: 8 - Sayı: 1

Thiol/disulphide balance and ischemia modified albumin levels in relapsed brucellosis patients

Pages
59–64
Publication Date
2022-10-18
DOI
—
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The levels of IMA were statistically significant in patients with relapsed brucellosis compared to the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: In the study, it was aimed to determine the Thiol/Disulphide profile in patients with relapsed brucellosis and the relationship between Ischemia Modified Albumin (IMA) Levels and Thiol/Disulphide profile.Methods: Native thiol, Total thiol, Disulphide, Disulphide/Native thiol, Disulphide/Total thiol, IMA levels were measured in forty patients with relapsed brucellosis and healthy control group by using the newly developed method in this cross-sectional study.Results: There was no statistically significant difference in patients with relapse brucellosis despite the fact that it was lower than total thiol control group (p > 0.05).
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Key Findings & Data:Disulphide was detected high in patients with brucellosis but no statistically significant difference was found (p > 0.05).
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Conclusion & Impact:The levels of IMA were statistically significant in patients with relapsed brucellosis compared to the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: In the study, it was aimed to determine the Thiol/Disulphide profile in patients with relapsed brucellosis and the relationship between Ischemia Modified Albumin (IMA) Levels and Thiol/Disulphide profile.Methods: Native thiol, Total thiol, Disulphide, Disulphide/Native thiol, Disulphide/Total thiol, IMA levels were measured in forty patients with relapsed brucellosis and healthy control group by using the newly developed method in this cross-sectional study.Results: There was no statistically significant difference in patients with relapse brucellosis despite the fact that it was lower than total thiol control group (p > 0.05). Disulphide was detected high in patients with brucellosis but no statistically significant difference was found (p > 0.05). Native thiol and total thiol ratios of disulphide were found to be statistically higher in patients with relapsed brucellosis (p < 0.05). In addition, the ratio of native thiol and native thiol to total thiol was statistically lower than the control group (p < 0.05). The levels of IMA were statistically significant in patients with relapsed brucellosis compared to the control group (p

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Cite This Article

BİÇER, C. K., BARAN, P., KURT, A., ASLAN, M. H., YILMAZ, S. İ., KARAŞAHİN, Ö. (2022). Thiol/disulphide balance and ischemia modified albumin levels in relapsed brucellosis patients. The European Research Journal, Cilt: 8 - Sayı: 1, 59–64. https://ajindex.com/articles/597300

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