Journals / Southern Clinics of Istanbul Eurasia / 2019 / Cilt: 30 - Sayı: 1

Malignancy in Renal Transplant Recipients

Böbrek Nakli Alıcılarında Malignite

Pages
43–46
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Renal transplantation is the most favorable renal replacement therapy,and complications, such as malignancy, that may develop later should be a cause to follow-upthis treatment more carefully during the course of the procedure.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The types of post-transplantation malignancies may vary among different geographic regions and ethnic populations.
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Key Findings & Data:The aim of the present study was to determinethe risk and incidence of de novo carcinomas, clinical characteristics, and outcomes in renaltransplant recipients (RTRs) who are followed up in our center and if there is an accumulation of one type of malignity and to examine screening procedures and frequency.Methods: The files of 322 RTRs who were transplanted between January 1, 2005 and December 31, 2016 were screened retrospectively.
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Conclusion & Impact:Renal transplantation is the most favorable renal replacement therapy,and complications, such as malignancy, that may develop later should be a cause to follow-upthis treatment more carefully during the course of the procedure.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The types of post-transplantation malignancies may vary among different geographic regions and ethnic populations. The aim of the present study was to determinethe risk and incidence of de novo carcinomas, clinical characteristics, and outcomes in renaltransplant recipients (RTRs) who are followed up in our center and if there is an accumulation of one type of malignity and to examine screening procedures and frequency.Methods: The files of 322 RTRs who were transplanted between January 1, 2005 and December 31, 2016 were screened retrospectively. The main data included the date of transplantation, patients’ age, gender, date of the last follow-up, and cancer diagnosis.Results: In eight patients (M/F=7/1), de novo malignancy was identified. The mean age ofpatients with malignancy was 54.87±12.5 years. The median duration of dialysis was 44 (2–107) months. The average time from transplantation to tumor development was 50 (7–93)months. Malignity development rate was found to be 2.5% among all RTRs.Conclusion: Every patient with renal transplantation should be followed up carefully byregular physical examination, laboratory findings, and imaging studies due to the risk ofmalignancy. Early diagnosis of malignancy is very important for both patient survival andfunctional renal graft. Renal transplantation is the most favorable renal replacement therapy,and complications, such as malignancy, that may develop later should be a cause to follow-upthis treatment more carefully during the course of the procedure.

Özet

Amaç: Transplantasyon sonrası gelişen malignitelerin tipi coğrafi ve etnik popülasyonlar arasında farlılıklar göstermektedir. Çalışmamızda böbrek nakli alıcılarında malignite gelişimi riski ve sıklığını, klinik özellikleri ve sonuçlarını değerlendirmeyi amaçladık. Gereç ve Yöntem: Merkezimizde Ocak 2005 ile Aralık 2016 arasında takip edilen 322 böbrek nakli alıcısı değerlendirmeye alındı. Nakil tarihi, demografik veriler, kanser tanısıyla ilgili veriler kayıt edildi. Bulgular: Yedi erkek ve bir kadın olguda malignite geliştiği görüldü. Yaş ortalaması 54.87±12.5 idi. Ortalama dializ süresi 44 (2–107) aydı. Nakilden malignite tanısına kadar geçen süre 50 (dağılım, 7–93) aydı. Tün böbrek nakli alıcıları arasında malignite gelişme oranı %2.5 olarak hesaplandı. Sonuç: Transplantasyn uygulanan olguların malignite yönünden fizik muayene, laboratuvar değerlendirmesi ve görüntüleme yöntemleri ile yakın takibi gerekir. Erken tanı, hastanın ve nakil böbreğin sağkalımı için hayati değerdedir.

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Cite This Article

YALIN, S. F., MEŞE, M., HARAS, A. B., AKYÜZ, O., PARMAKSIZ, E., BAHÇABAŞI, Z. B. (2022). Malignancy in Renal Transplant Recipients. Southern Clinics of Istanbul Eurasia, Cilt: 30 - Sayı: 1, 43–46. https://ajindex.com/articles/592874

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