Journals / Southern Clinics of Istanbul Eurasia / 2019 / Cilt: 30 - Sayı: 3

Evaluation of Blood Gas Analysis as a Mortality Predictor

Mortalite Prediktörü Olarak Kan Gazı Analizinin Değerlendirilmesi

Pages
228–231
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the non-survivor group (mean±SD)-5.57±9.852 mmol/L values for the base deficit was found to be meaningful in terms of mortality (p=0.000).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: This study examines the effects of the blood gas analysis on mortality.
📊
Key Findings & Data:Thismethod may contribute to decreasing mortality rates in intensive care wards and emergencyrooms.Methods: The study uses the data that was retrospectively derived and analyzed frompatients who were admitted to Haydarpasa Numune Education and Research Hospital Emergency Room between January 2016-January 2017.
💡
Conclusion & Impact:In the non-survivor group (mean±SD)-5.57±9.852 mmol/L values for the base deficit was found to be meaningful in terms of mortality (p=0.000).
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: This study examines the effects of the blood gas analysis on mortality. Thismethod may contribute to decreasing mortality rates in intensive care wards and emergencyrooms.Methods: The study uses the data that was retrospectively derived and analyzed frompatients who were admitted to Haydarpasa Numune Education and Research Hospital Emergency Room between January 2016-January 2017. Two hundred seventy-four patients addedto this study, and the data were taken from the patient’s first blood gas analysis.Results: Our study showed us lactate, base excess, bicarbonate levels can have a relationwith mortality. Statistical analysis for lactate had 4.64±4.696 mEq/L values, and it was significant for mortality in the non-survival group (p=0.000). In the ROC analysis of the lactate,the area under the curve was determined as 0.725, and when the lactate was above 1.5mEq/L, it had 76% sensitivity and 54% specificity. In the non-survivor group (mean±SD)-5.57±9.852 mmol/L values for the base deficit was found to be meaningful in terms of mortality (p=0.000). The area under the curve was 0.726 as a result of the ROC analysis of thebase excess, with a sensitivity of 63% and a specificity of 74.7% for the value of -2.5 mmol/L.The statistics for bicarbonate (mean±SD) 19.63±7.725 mmol/L range values are significantas predictors of mortality (p0.05).Conclusion: As a result of the data obtained in our study, the findings suggest that thevalues of lactate, bicarbonate and base deficit could be the predictors of mortality.

Özet

Amaç: Bu çalışma kan gazı analizinin mortalite üzerindeki etkilerini incelemektedir. Bu yöntem yoğun bakımlarda ve acil servislerde mortalite oranlarının azaltılmasına katkıda bulunabilir. Gereç ve Yöntem: Çalışma verileri Ocak 2016–Ocak 2017 tarihleri arasında Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Acil Servisi’ne getirilen hastalardan geriye dönük olarak edinildi ve analiz edildi. Bu çalışmaya 274 hasta alındı, hasta verileri acil servis başvurularındaki ilk kan gazı kayıtlarından alındı. Bulgular: Çalışmamız bize laktat, baz açığı ve bikarbonat düzeylerinin mortalite ile ilişkili olabileceğini gösterdi. Laktat için istatistiksel analiz sağkalım olmayan grupta 4.64±4.696 mEq/L değerlerine sahipti ve mortalite açısından anlamlıydı (p=0.000). Laktatın ROC analizinde, eğri altındaki alan 0.725 olarak belirlenmiştir. Laktat 1.5 mEq/L’nin üzerinde olduğunda, %76 duyarlılığa ve %54 özgüllüğe sahiptir. Hayatta kalan grupta (ortalama±SS), baz açığı için -5.57±9.852 mmol/L değerlerinin mortalite açısından anlamlı olduğu bulundu (p=0.000). Eğri altındaki alan, baz açığı için, -2.5 mmol/L değerinde ROC analizi sonucunda 0.726 bulundu. Bu değerin %63 duyarlılık ve %74.7 özgüllüğe sahip olduğu tespit edildi. Bikarbonat için (ortalama±SS) 19.63±7.725 mmol/L aralığı değerleri mortalitenin prediktörü olarak anlamlı bulundu (p0.05). Sonuç: Çalışmamızda elde edilen veriler sonucunda laktat, bikarbonat ve baz açığı değerlerinin mortalite prediktörü olabileceği belirlenmiştir.

🔖

Cite This Article

KORKMAZ, S., ERDOĞAN, M. Ö., TEKYOL, D., SEYHAN, A. U., YILMAZ, E., HÖKENEK, N. M. (2022). Evaluation of Blood Gas Analysis as a Mortality Predictor. Southern Clinics of Istanbul Eurasia, Cilt: 30 - Sayı: 3, 228–231. https://ajindex.com/articles/592842

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Zimmerman JE, Kramer AA, McNair DS, Malila FM. Acute Physiology and Chronic Health Evaluation (APACHE) IV: hospital mortality assessment for today’s critically ill patients. Crit Care Med 2006;34:1297–310
  2. Davis JW. The relationship of base deficit to lactate in porcine hemorrhagic shock and resuscitation. J Trauma 1994;36:168–72
  3. Parker MM, Shelhamer JH, Natanson C, Alling DW, Parrillo JE. Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: heart rate as an early predictor of prognosis. Crit Care Med 1987;15:923–9
  4. Bernardin G, Pradier C, Tiger F, Deloffre P, Mattei M. Blood pressure and arterial lactate level are early indicators of short-term survival in human septic shock. Intensive Care Med 1996;22:17–25
  5. Davis JW, Kaups KL, Parks SN. Base deficit is superior to pH in evaluating clearance of acidosis after traumatic shock. J Trauma 1998;44:114–8 6. Siegel JH, Rivkind AI, Dalal S, Goodarzi S. Early physiologic predictors of injury severity and death in blunt multiple trauma. Arch Surg 1990;125:498–508
  6. Dunham CM, Siegel JH, Weireter L, Fabian M, Goodarzi S, Guadalupi P, et al. Oxygen debt and metabolic acidemia as quantitative predictors of mortality and the severity of the ischemic insult in hemorrhagic shock. Crit Care Med 1991;19:231–43
  7. Davis JW, Shackford SR, Holbrook TL. Base deficit as a sensitive indicator of compensated shock and tissue oxygen utilization. Surg Gynecol Obstet 1991;173:473–6
  8. Davis JW, Kaups KL. Base deficit in the elderly: a marker of severe injury and death. J Trauma 1998;45:873–7
  9. Davis JW, Mackersie RC, Holbrook TL, Hoyt DB. Base deficit as an indicator of significant abdominal injury. Ann Emerg Med 1991;20:842–4.