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Journals / Southern Clinics of Istanbul Eurasia / 2020 / Cilt: 31 - Sayı: 1

Evaluation of Risk Factors for Carbapenem-Resistant Klebsiella Pneumoniae Bacteremia

Klebsiella Pneumoniae Bakteriyemilerinde Karbapenem Direnci İçin Risk Faktörlerinin Değerlendirilmesi

Ayşe BATIREL
Pınar KIRAN
Serap GENCER
Pages
54–58
Publication Date
2022-10-19
DOI
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Risk factors for carbapenem-resistant K. pneumoniae bacteremia accordingto univariate analysis were listed prior hospitalization (p=0.043; OR=3.20; 95% CI: 1.04–9.85), admission to intensive care unit (p=0.001; OR=10.91; 955 CI: 2.61–45.6), use of beta-lactams/beta-lactamase inhibitor combination (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In recent years, carbapenem-resistant Klebsiella pneumoniae infections havebecome an important health problem in our country and all over the world.
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Key Findings & Data:In this study,we aimed to identify the risk factors of carbapenem-resistant K. pneumoniae bacteremia.Methods: Patients who suffered from Klebsiella pneumoniae bacteremia between December2016 and May 2018 were included prospectively in this study.
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Conclusion & Impact:Risk factors for carbapenem-resistant K. pneumoniae bacteremia accordingto univariate analysis were listed prior hospitalization (p=0.043; OR=3.20; 95% CI: 1.04–9.85), admission to intensive care unit (p=0.001; OR=10.91; 955 CI: 2.61–45.6), use of beta-lactams/beta-lactamase inhibitor combination (p
🔬Design:Modeling & Simulation
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In recent years, carbapenem-resistant Klebsiella pneumoniae infections havebecome an important health problem in our country and all over the world. In this study,we aimed to identify the risk factors of carbapenem-resistant K. pneumoniae bacteremia.Methods: Patients who suffered from Klebsiella pneumoniae bacteremia between December2016 and May 2018 were included prospectively in this study. Patients were divided intogroups according to carbapenem resistance and risk factors were analyzed under variableand multivariable logistic regression model.Results: Of the fifty-three patients were included in this study, 27 patients infected withcarbapenem-resistant K. pneumoniae and 26 patients infected with carbapenem-suspectibleK. pneumoniae. Risk factors for carbapenem-resistant K. pneumoniae bacteremia accordingto univariate analysis were listed prior hospitalization (p=0.043; OR=3.20; 95% CI: 1.04–9.85), admission to intensive care unit (p=0.001; OR=10.91; 955 CI: 2.61–45.6), use of beta-lactams/beta-lactamase inhibitor combination (p

Özet

Amaç: Son yıllarda artan karbapenem direnci ile birlikte Klebsiella pneumoniae enfeksiyonları ülkemizde ve tüm dünyada önemli bir sağlık problemi haline gelmiştir. Bu çalışmada, Klebsiella pneumoniae bakteriyemilerinde karbapenem direnci için risk faktörlerini belirlemeyi amaçladık. Gereç ve Yöntem: Aralık 2016–Mayıs 2018 tarihleri arasında kan kültüründe Klebsiella pneumoniae üremesi olan hastalar ileriye yönelik olarak çalışmaya dahil edildi. Olgular karbapenem direnç durumuna göre gruplara ayrılarak; tek ve çok değişkenli regresyon modeli ile karbapenem direnci için risk faktörleri analiz edildi. Bulgular: Çalışmaya dahil edilen 53 olgunun; 27’si karbapenem dirençli, 26’sı ise karbapenem duyarlı Klebsiella pneumoniae izolatı ile enfekte idi. Yapılan tek değişken analiz sonuçlarına göre; hastaneye yatış öyküsü [p=0.043; Odds ratio (OR)=3.20; %95 güven aralığı (%95 GA): 1.04–9.85], yoğun bakım ünitesinde (YBÜ) yatıyor olmak (p=0.001; OR=10.91; %95 GA 2.61–45.6), beta-laktam/beta-laktam inhibitörü kombinasyonu kullanımı (p

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Cite This Article

BATIREL, A., KIRAN, P., GENCER, S. (2022). Evaluation of Risk Factors for Carbapenem-Resistant Klebsiella Pneumoniae Bacteremia. Southern Clinics of Istanbul Eurasia, Cilt: 31 - Sayı: 1, 54–58. https://ajindex.com/articles/592780

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