SavedAdd your journal

Journals / Southern Clinics of Istanbul Eurasia / 2021 / Cilt: 32 - Sayı: 4

Relationship Between Helicobacter Pylori and Intestinal Metaplasia: A Rural Hospital Experience

Özlem Güngör
Ozan Akıncı
Sefa Ergün
Sangar M Faroq Abdulrahman Abdulrahman
Erdem Çomut
Pages
345–349
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The rate of IM was significantly higher in Hp-positive patients than in Hp-negative patients (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Helicobacter pylori (Hp) is a risk factor for gastric cancer, and intestinal meta- plasia (IM) is one of the precursor lesions of gastric cancer.
📊
Key Findings & Data:Methods: A total of 550 patients who underwent upper gastrointestinal endoscopy be- tween October 2018 and December 2019 were included in the study.
💡
Conclusion & Impact:The rate of IM was significantly higher in Hp-positive patients than in Hp-negative patients (p
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Helicobacter pylori (Hp) is a risk factor for gastric cancer, and intestinal meta- plasia (IM) is one of the precursor lesions of gastric cancer. The aim of this study was to examine the relationship between Hp and IM. Methods: A total of 550 patients who underwent upper gastrointestinal endoscopy be- tween October 2018 and December 2019 were included in the study. The patient data of age, sex, endoscopic diagnosis, Hp positivity, IM, atrophic gastritis, and neoplasia were evaluated retrospectively. Results: There were 550 patients enrolled in the study: 228 males (41.5%) and 322 females (59.5%), with a median age of 37.0 years (interquartile range: 18.0–79.0 years). Hp was de- tected in 62.7% of the patients, IM in 17.1%, gastric atrophy in 9.1%, and gastric cancer in 2.9%. Among the patients with positive IM, 80 were Hp-positive and 14 were Hp-negative. The rate of IM was significantly higher in Hp-positive patients than in Hp-negative patients (p

🔖

Cite This Article

Güngör, Ö., Akıncı, O., Ergün, S., Abdulrahman, S. M. F. A., Çomut, E. (2022). Relationship Between Helicobacter Pylori and Intestinal Metaplasia: A Rural Hospital Experience. Southern Clinics of Istanbul Eurasia, Cilt: 32 - Sayı: 4, 345–349. https://ajindex.com/articles/592750

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Warren JR, Marshall B. Unidentified curved bacilli on gastric epithe- lium in active chronic gastritis. Lancet 1983;1:1273–5
  2. Mercer DW, Robinson EK. Mide. In: Ulusoy AN, Topgül K, editors. Sabiston textbook of surgery. 17th ed. Philadelphia: Elsevier Saun- ders; 2010. p. 1265−321
  3. An international association between helicobacter pylori infec- tion and gastric cancer. The EUROGAST Study Group. Lancet 1993;341:1359−62
  4. Bravo D, Hoare A, Soto C, Valenzuela MA, Quest AF. Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects. World J Gastroenterol 2018;24:3071−89
  5. Correa P, Piazuelo MB, Camargo MC. The future of gastric cancer prevention. Gastric Cancer 2004;7:9−16
  6. Díaz P, Valenzuela Valderrama M, Bravo J, Quest AFG. Helicobacter pylori and gastric cancer: adaptive cellular mechanisms involved in disease progression. Front Microbiol 2018;9:5
  7. Zhao Y, Zhang J, Cheng ASL, Yu J, To KF, Kang W. Gastric cancer: genome damaged by bugs. Oncogene 2020;39:3427−42
  8. Infection with helicobacter pylori. IARC Monogr Eval Carcinog Risks Hum 1994;61:177−240
  9. Rugge M, Genta RM, Di Mario F, El-Omar EM, El-Serag HB, Fas- san M, et al. Gastric Cancer as Preventable Disease. Clin Gastroen- terol Hepatol 2017;15:1833−43
  10. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grad- ing of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 1996;20:1161−81
  11. Brown LM. Helicobacter pylori: epidemiology and routes of trans- mission. Epidemiol Rev 2000;22:283−97
  12. Ohkuma K, Okada M, Murayama H, Seo M, Maeda K, Kanda M, et al. Association of helicobacter pylori infection with atrophic gastritis and intestinal metaplasia. J Gastroenterol Hepatol 2000;15:1105−12
  13. Huang JQ, Sridhar S, Chen Y, Hunt RH. Meta-analysis of the rela- tionship between helicobacter pylori seropositivity and gastric cancer. Gastroenterology 1998;114:1169−79
  14. Helicobacter and Cancer Collaborative Group. Gastric cancer and he- licobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut 2001;49:347−53
  15. Cavaleiro-Pinto M, Peleteiro B, Lunet N, Barros H. Helicobacter pylori infection and gastric cardia cancer: systematic review and me- ta-analysis. Cancer Causes Control 2011;22:375−87
  16. Ford AC, Forman D, Hunt RH, Yuan Y, Moayyedi P. Helicobacter pylori eradication therapy to prevent gastric cancer