Long-term Outcomes of Gamma-Knife Radiosurgery for Intracanalicular Vestibular Schwannomas

Follow-up duration over 5 years may diminish functional hearing preservation rates, and more studies are needed with long-term follow-up to clarify the actual course of hearing status after GKR in IVS.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Intracanalicular vestibular schwannomas (IVS) constitute a small percentage of all vestibular schwannomas (VS).

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Key Findings & Data:Methods: Patients with IVS who were irradiated at our Gamma-Knife Radiosurgery Center between January 2010 and January 2020 with clinical, audiometric, and radiological follow-up were included in this retrospective study.

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Conclusion & Impact:Follow-up duration over 5 years may diminish functional hearing preservation rates, and more studies are needed with long-term follow-up to clarify the actual course of hearing status after GKR in IVS.

🔬Design:Research Article

📍Scope:2010 Verileri

⚙️Variables:Domain Parameters

Abstract

Objective: Intracanalicular vestibular schwannomas (IVS) constitute a small percentage of all vestibular schwannomas (VS). Hearing preservation is one of the most important goals in IVS management. The aim of this study was to delineate the long-term outcomes of gamma-knife radiosurgery (GKR) for IVS regarding tumor control and hearing preser- vation. Methods: Patients with IVS who were irradiated at our Gamma-Knife Radiosurgery Center between January 2010 and January 2020 with clinical, audiometric, and radiological follow-up were included in this retrospective study. Tumor control was evaluated with magnetic res- onance imaging by tumor dimensions. Hearing status was classified according to Gardner– Robertson (GR) classification system. Results: Tumor control was achieved in 44 of 45 eligible patients by dimensional measuring (97.8%), and the remaining patient did not require further treatment (2.2%). In 29 patients who had functional hearing (GR grades I and II), only 13 patients preserved their functional hearing with a mean of 70.42 months follow-up (44.8%). A GR grade loss in hearing was correlated with a high GR grade preoperatively (Rs=0.459, p=0.002). Treatment dose was also found to be correlated with hearing loss, and higher doses resulted in worse outcomes (Rs=0.459, p=0.002). Conclusion: GKR has excellent results on tumor control on long-term follow-up in IVS. Follow-up duration over 5 years may diminish functional hearing preservation rates, and more studies are needed with long-term follow-up to clarify the actual course of hearing status after GKR in IVS.

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Cite This Article

Ziyal, İ., Atasoy, B., Bayraklı, F., Sakar, M., Pınar, E., Kıvrak, C., Bayri, Y. (2022). Long-term Outcomes of Gamma-Knife Radiosurgery for Intracanalicular Vestibular Schwannomas. Southern Clinics of Istanbul Eurasia, Cilt: 33 - Sayı: 2, 203–208. https://ajindex.com/articles/592706

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