Journals / Selçuk Tıp Dergisi / 2020 / Cilt: 36 - Sayı: 3

Aeroallergen Sensitivity of Atopic Children in Alanya Region

Alanya Bölgesinde Atopik Çocuklarda Aeroalerjen Duyarlılığı

Pages
226–231
Publication Date
2022-10-17
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The mean serum total IgE level was 215.6 IU/ml and the mean eosinophil count was 410.63/mm³.Conclusion: Detection of responsible allergens is important to control symptoms and to give the chance the course of the disease with immunotherapy in the selected cases.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: It is important to identify allergens in reducing disease-related symptoms and improving quality of life in the allergic diseases.
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Key Findings & Data:Therefore, we aimed to evaluate the frequency of aeroallergens in allergic patients in our region.Patients and Methods: 1078 patients (2-18 years) who applied to the pediatric allergy immunology outpatient clinic between September 2017- March 2018 were included to the study.
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Conclusion & Impact:The mean serum total IgE level was 215.6 IU/ml and the mean eosinophil count was 410.63/mm³.Conclusion: Detection of responsible allergens is important to control symptoms and to give the chance the course of the disease with immunotherapy in the selected cases.
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: It is important to identify allergens in reducing disease-related symptoms and improving quality of life in the allergic diseases. Therefore, we aimed to evaluate the frequency of aeroallergens in allergic patients in our region.Patients and Methods: 1078 patients (2-18 years) who applied to the pediatric allergy immunology outpatient clinic between September 2017- March 2018 were included to the study. The demographic and clinical characteristics of 642 patients with at least one allergic sensitization in the skin prick test were evaluated retrospectively. Total IgE levels, peripheral eosinophil counts in the blood, aeroallergen sensitivities in skin prick test were evaulated from the patient’s files. The study was approved by the Ethics Committee of the Alanya Alaaddin Keykubat Medical Faculty.Results: In 642 of the patients (59.5%), a positive response was observed against at least one aeroallergen. Among patients, 34.8% had asthma, 73.7% had allergic rhinitis, 12.6% had atopic dermatitis, and 3% had chronic urticaria. 24.8% of the patients (159) had more than one allergic disease. When the evaulation of the patients with positive skin prick test, 57.3% were male and 42.7% were female. The mean age was 8.49 +/- 4.15 years. The sensitivity of house dust mites was the most common (76.1%). In the second and third frequency, molds (51.8% Alternaria alternata, 41.7% Claudosporum herbarum) and grass and cereal pollen (39.8%) sensitivity were observed. Other determined aeroallergen sensitivity frequencies were; weed pollen mixture (24.6%), trees pollen mixture (21.7%), cockroach (17.8%), cat hair (31.2%), olive tree (20%). The mean serum total IgE level was 215.6 IU/ml and the mean eosinophil count was 410.63/mm³.Conclusion: Detection of responsible allergens is important to control symptoms and to give the chance the course of the disease with immunotherapy in the selected cases.

Özet

Amaç: Alerjik hastalıklarda semptomları azaltmak ve yaşam kalitesini arttırmak için sorumlu alerjenleri belirlemek önemlidir. Bu nedenle bölgemizdeki alerjik hastalarda aeroalerjenlerin duyarlılığını ve sıklığını değerlendirmeyi amaçladık. Hastalar ve Yöntem: Çalışmaya, Eylül 2017-Mart 2018 tarihleri arasında pediatrik alerji immünoloji polikliniğine başvuran 1078 hasta (2-18 yaş) dahil edildi. Deri prick testinde en az bir alerjik duyarlılık saptanan 642 hastanın klinik ve demografik özellikleri, total IgE düzeyleri, kandaki periferik eozinofil sayıları, aeroalerjen duyarlılıkları hasta dosyalarından retrospektif olarak değerlendirildi. Çalışma için Alanya Alaaddin Keykubat Üniversitesi Tıp Fakültesi Yerel Etik Kurulundan onay alındı. Bulgular: Hastaların 642'sinde (%59.5) en az bir aeroalerjene karşı pozitif yanıt gözlendi. Hastaların %34.8'inde astım, %73.7'sinde alerjik rinit, %12.6'sında atopik dermatit ve %3'ünde kronik ürtiker tanısı vardı. 159 (%24.8) hastada birden fazla alerjik hastalık tanısı vardı. Pozitif cilt prick testi olan hastaların 368’i (%57.3) erkek, 274’ü (%42.7) kızdı. Yaş ortalaması 8.49±4.15 yıldı. En sık Akar duyarlılığı saptandı (%76.1). İkinci sıklıkta küf mantarları (51.8% Alternaria alternata, 41.7% Claudosporum herbarum) ve üçüncü sıklıkta grass ve cereal polen (39.8%) duyarlılığı gözlendi. Diğer aeroalerjen duyarlılık sıklıkları; yabani ot polen karışımı (%24.6), ağaç polen karışımı (%21.7), hamamböceği (%17.8), kedi tüyü (%31.2), zeytin ağacı (%20) olarak saptandı. Ortalama serum total IgE düzeyi 215.6 IU/ml ve ortalama eozinofil sayısı 410.63/mm³ idi. Sonuç: Alerjik hastalıklarda sorumlu alerjenlerin tespit edilmesi semptomların kontrol edilmesi ve seçilmiş vakalarda immünoterapi şansı vererek hastalık seyrini değiştirebilmesi açısından önemlidir.

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Cite This Article

SAYAR, E. H. (2022). Aeroallergen Sensitivity of Atopic Children in Alanya Region. Selçuk Tıp Dergisi, Cilt: 36 - Sayı: 3, 226–231. https://ajindex.com/articles/591812

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