Journals / Selçuk Tıp Dergisi / 2021 / Cilt: 37 - Sayı: 1

Analysis of Ganglion Cell Complex and Retinal Nerve Fiber Layer Thicknesses in Turkish Population

Türk Halkında Ganglion Hücre Kompleksinin ve Retina Sinir Lifi Kalınlığının Değerlendirilmesi

Pages
17–23
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The mean retinal nerve fiber layerand ganglion cell complex thicknesses exhibited a significant c orrelation.Conclusion: The ganglion cell complex thickness and retinal nerve fiber layer thickness decreasedsignificantly with age but ganglion cell complex thickness was less af fected.

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Objective & Hypothesis:Aim: To determine the effects of age and sex on retinal ganglion cell complex thickness and retinal nervefiber layer thickness in the eyes of healthy individuals.Patients and Methods: We evaluated 393 healthy subjects aged 10-84 years in a cross-sectional studybetween November 2012 and May 2013.
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Key Findings & Data:We evaluated the relationship betweenthe retinal nerve fiber layer thickness and ganglion cell compl ex thickness using Pearson’ s correlation.Results: The whole population mean retinal nerve fiber layer thickness was 108.94±9.77 μm, anddecreased by 0.101 μm/year.
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Conclusion & Impact:The mean retinal nerve fiber layerand ganglion cell complex thicknesses exhibited a significant c orrelation.Conclusion: The ganglion cell complex thickness and retinal nerve fiber layer thickness decreasedsignificantly with age but ganglion cell complex thickness was less af fected.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: To determine the effects of age and sex on retinal ganglion cell complex thickness and retinal nervefiber layer thickness in the eyes of healthy individuals.Patients and Methods: We evaluated 393 healthy subjects aged 10-84 years in a cross-sectional studybetween November 2012 and May 2013. Linear regression analysis and Pearson’s correlation wereperformed to analyze the difference in the age-related changes. We evaluated the relationship betweenthe retinal nerve fiber layer thickness and ganglion cell compl ex thickness using Pearson’ s correlation.Results: The whole population mean retinal nerve fiber layer thickness was 108.94±9.77 μm, anddecreased by 0.101 μm/year. The most significant decrease was in the supero-temporal sector. There wasno difference in the retinal nerve fiber layer thickness between sexes, except for the superior quadrant.The mean ganglion cell complex thickness was 97.45±6.42 μm, and decreased by 0.043 μm/year. Therewas no relationship between sex and ganglion cell complex thickness. The mean retinal nerve fiber layerand ganglion cell complex thicknesses exhibited a significant c orrelation.Conclusion: The ganglion cell complex thickness and retinal nerve fiber layer thickness decreasedsignificantly with age but ganglion cell complex thickness was less af fected.

Özet

Amaç: Sağlıklı bireylerde yaş ve cinsiyetin ganglion hücre kompleksi ve retina sinir lifi kalınlığı üzerine etkisinin değerlendirilmesi amaçlandı. Hastalar ve Yöntem: Bu kesitsel çalışmada Kasım 2012 - Mayıs 2013 tarihleri arasında yaşları 10-84 arasında değişen 393 sağlıklı katılımcıyı değerlendirdik. Yaşa bağlı değişikler lineer regresyon analizi ve Pearson korelasyon analizi ile incelendi. Retina sinir lifi kalınlığı ve ganglion hücre kompleksi arasındaki ilişki pearson korelasyon testi ile değerlendirildi. Bulgular: Tüm populasyonun ortalama retina sinir lifi kalınlığı 108.94±9.77 μm idi ve yıllık 0.101 μm azalmaktaydı. En önemli azalma üst temporal bölümde görüldü. Üst kadran hariç retina sinir lifi kalınlığında cinsiyete göre fark bulunamadı. Ortalama ganglion hücre kompleksi kalınlığı 97.45±6.42 μm olarak bulundu ve her yıl 0.043 μm azalmaktaydı. Cinsiyetle ganglion hücre kalınlığı arasında bir ilişki bulunmazken retina sinir lifi ile ganglion hücre kompleksi aras ında anlamlı korelasyon tespit edilmiştir . Sonuç: Retina sinir lifi kalınlığı ve ganglion hücre kompleksi kalınlığı yaşla birlikte önemli ölçüde azalmaktadır ancak ganglion hücre kalınlığı daha az etkilenmekt edir.

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Cite This Article

BAYHAN, H. A., ADAM, M., BAYHAN, S. A., MUHAFIZ, E., BEKDEMİR, Ş., GÜRDAL, C. (2022). Analysis of Ganglion Cell Complex and Retinal Nerve Fiber Layer Thicknesses in Turkish Population. Selçuk Tıp Dergisi, Cilt: 37 - Sayı: 1, 17–23. https://ajindex.com/articles/591767

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