Journals / Respiratory Case Reports / 2020 / Cilt: 9 - Sayı: 3

Effectiveness of Favipiravir prior to Admission to the Intensive Care Unit in COVID-19 Pneumonia

COVID-19 Pnömonisinde Yoğun Bakım Ünitesi Öncesinde Favipiravir'in Etkinliği

Pages
99–103
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the current paper we presented four cases with worsening clinical conditions and the development of hypoxia who were treated with Favipiravir before being admitted to the intensive care unit, and who recovered from the disease.

📌 3 Key Takeaways

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Objective & Hypothesis:After emerging in Wuhan city in December 2019, the coronavirus disease 2019 (COVID-19) rapidly spread throughout China.
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Key Findings & Data:Although high rates of hospitalization are seen with COVID-19, no specific treatment has been reported, and the choice of antiviral therapies is limited.
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Conclusion & Impact:In the current paper we presented four cases with worsening clinical conditions and the development of hypoxia who were treated with Favipiravir before being admitted to the intensive care unit, and who recovered from the disease.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

After emerging in Wuhan city in December 2019, the coronavirus disease 2019 (COVID-19) rapidly spread throughout China. Although high rates of hospitalization are seen with COVID-19, no specific treatment has been reported, and the choice of antiviral therapies is limited. Favipiravir, approved in Japan for influenza, is one of the drugs that targets RNA-dependent RNA polymerase (RdRP). It significantly decreases the duration of fever, cough dyspnea, and the need of oxygen therapy or noninvasive mechanical ventilation, especially in moderate COVID-19 cases. In the current paper we presented four cases with worsening clinical conditions and the development of hypoxia who were treated with Favipiravir before being admitted to the intensive care unit, and who recovered from the disease.

Özet

Aralık 2019'da Wuhan şehrinde ortaya çıkmasından bu yana, koronavirüs hastalığı (COVID-19) Çin'e hızla yayıldı. COVID-19 enfeksiyonuna bağlı yüksek oranda hastaneye yatış görülmesine rağmen, spesifik bir tedavi bildirilmemiştir. Bu bağlamda antiviral tedavi seçimi sınırlıdır. Japonya'da influenza için onaylanan Favipiravir, RNA'ya bağımlı RNA polimerazı (RdRP) hedefleyen ilaçlardan biridir. Özellikle orta şiddetteki COVID-19 olgularında ateş, öksürük dispnesi ve oksijen tedavisi veya noninvazif mekanik ventilasyon ihtiyacını önemli ölçüde azalttığı bilinmektedir. Bu yazıda, hastaları yoğun bakım ünitesine kabul etmeden önce klinik durumları kötüleşen ve favipiravir ile takip edilerek iyileşen dört olguyu sunduk.

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Cite This Article

ŞİRİN, F. B., KAYA, O., TEMEL, E. N., ÜNAL, O., YILMAZ, G. R., AKÇAM, F. Z., ŞİRİN, M. C., BAĞLAN, V., AYYILDIZ, V. A., ÇAKIR, M., AKKAYA, A., ÖZTÜRK, Ö. (2022). Effectiveness of Favipiravir prior to Admission to the Intensive Care Unit in COVID-19 Pneumonia. Respiratory Case Reports, Cilt: 9 - Sayı: 3, 99–103. https://ajindex.com/articles/588942

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