Journals / Respiratory Case Reports / 2021 / Cilt: 10 - Sayı: 2

A Case of Severe Plasmodium Vivax Infection Complicated by ARDS and Multiple Organ Involveme

ARDS ve Çoklu Organ Tutulumunun Neden Olduğu Şiddetli Plasmodium Vivax Enfeksiyonu Olgusu

Pages
95–100
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case is presented to emphasize the rare occurrence of ARDS and multiple organ failure in Plasmodium vivax infections.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Complicated malaria is caused mainly by Plasmodi- um falciparum, and increasingly nowadays by Plas- modium vivax.
📊
Key Findings & Data:A 49-year-old patient was operated due to squamous cell carcinoma.
💡
Conclusion & Impact:This case is presented to emphasize the rare occurrence of ARDS and multiple organ failure in Plasmodium vivax infections.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Complicated malaria is caused mainly by Plasmodi- um falciparum, and increasingly nowadays by Plas- modium vivax. We report a case of vivax malaria complicated by acute respiratory distress syndrome and treated with extracorporeal membrane oxygena- tion. A 49-year-old patient was operated due to squamous cell carcinoma. After a successful right upper lobectomy operation, he became hypoxemic and developed progressive bilateral lung infiltrates. He had fever, thrombocytopenia and splenomegaly that were not present in the preoperative timeline. A peripheral blood smear verified Plasmodium vivax infection. The patient deteriorated clinically and was intubated. A bronchoscopic evaluation revealed a fistula in the lobectomy stump. Veno-venous extra- corporeal membrane oxygenation was initiated due to refractory hypoxemia and to improve healing of the fistula. Our patient expired despite lung protective ventilation and extracorporeal membrane oxygena- tion support. This case is presented to emphasize the rare occurrence of ARDS and multiple organ failure in Plasmodium vivax infections.

Özet

Komplike malaryanın başlıca sebebi Plasmodium falciparum olmakla birlike, Plasmodium vivax sıklığı da giderek artmaktadır. Bu makalede, akut respira- tuar distres sendromu ile komplike olan ve ekstrakor- poreal membran oksijenasyonu desteği uyguladığımız bir hastamızı sunduk. Hasta 49 yaşında olup, skua- möz hücreli karsinom için yapılan sağ üst lobektomi operasyonundan sonra hipoksemi gelişti ve akciğer grafisinde ilerleyici bilateral infiltratlar ortaya çıktı. Preoperatif dönemde mevcut olmayan, ateş, trombo- sitopeni ve splenomegali görüldü. Periferik yayma yapıldı ve plasmodium vivax enfeksiyonu tespit edildi. Hipoksemisi derinleşti ve entübe edildi. Bronkoskopik değerlendirmede lobektomi güdüğünde fistül saptan- dı. Refrakter hipoksemi ve fistül iyileşmesi için venö- venöz ekstrakorporeal membran oksijenasyonu des- teğine alındı, ancak akciğer koruyucu ventilasyon stratejilerine ve ekstrakorporeal membran oksijenas- yonuna rağmen hasta kaybedildi. Bu olgu ile plasmodium vivax’ın nadiren akut respiratuar distres sendromu ve çoklu organ yetmezliğine neden olabi- leceğini vurgulamak istedik.

🔖

Cite This Article

Kıraklı, C., Yıldız, F., Ediboglu, O., Çinleti, B. A., Arabacı, B., Samancilar, O. (2022). A Case of Severe Plasmodium Vivax Infection Complicated by ARDS and Multiple Organ Involveme. Respiratory Case Reports, Cilt: 10 - Sayı: 2, 95–100. https://ajindex.com/articles/588883

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Agarwal R, Sehgal IS, Dhooria S, Aggarwal AN. Deve- lopments in the diagnosis and treatment of allergic bronchopulmonary aspergillosis. Expert Rev Respir Med 2016; 10:1317-34. [CrossRef] 2. Patel AR, Patel AR, Singh S, Singh S, Khawaja I. Diagno- sing allergic bronchopulmonary aspergillosis: a review. Cureus 2019; 27:11:e4550. [CrossRef] 3. Dixon WG, Abrahamowicz M, Beauchamp ME, Ray DW, Bernatsky S, Suissa S, et al. Immediate and delayed im- pact of oral glucocorticoid therapy on risk of serious in- fection in older patients with rheumatoid arthritis: a nes- ted case-control analysis. Ann Rheum Dis 2012; 71:1128-33. [CrossRef] 4. Cain DW, Cidlowski JA. Immune regulation by glucocor- ticoids. Nat Rev Immunol 2017;17:233-47. [CrossRef] 5. Walsh TJ, Anaissie EJ, Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, et al. Treatment of aspergillo- sis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis 2008; 46:327-60. [CrossRef] 6. El-Baba F, Gao Y, Soubani AO. Pulmonary aspergillosis: what the generalist needs to know. Am J Med 2020; 133:668-674. [CrossRef] 7. Takazono T, Sheppard DC. Aspergillus in chronic lung disease: modeling what goes on in the airways. Med My- col 2017; 55:39-47. [CrossRef] 8. Azoulay E, Russell L, Van De Louw A, Metaxa V, Bauer P, Povoa P, et al. Diagnosis of severe respiratory infections in immunocompromised patients. Intensive Care Med 2020; 46:298-314. [CrossRef] 9. Lam JM. Opportunistic fungal infection in children and management. Curr Opin Pediatr 2018; 30:514-9. [CrossRef] 10. Barnes PD, Marr KA. Aspergillosis: spectrum of disease, diagnosis, and treatment. Infect Dis Clin North Am 2006; 20:545-61. [CrossRef] 11. Rementeria A, Lopez-Molina N, Ludwig A, Vivanco AB, Bikandi J, Pontón J, et al. Genes and molecules involved in Aspergillus fumigatus virulence. Rev Iberoam Micol 2005; 22:1-23. [CrossRef] 12. Horvath JA, Dummer S. The use of respiratory-tract cul- tures in the diagnosis of invasive pulmonary aspergillosis. Am J Med 1996; 100:171-8. [CrossRef] 13. Stone S, Lynch D. Learning points for clinicians. Available from: https://academic.oup.com/qjmed/article/111/11/807/5 033838 [CrossRef] 14. Becker MJ, Lugtenburg EJ, Cornelissen JJ, Van Der Schee C, Hoogsteden HC, De Marie S. Galactomannan detec- tion in computerized tomography-based broncho- alveolar lavage fluid and serum in haematological pa- tients at risk for invasive pulmonary aspergillosis. Br J Haematol 2003; 121:448-57. [Cross