Journals / Osmangazi Tıp Dergisi / 2021 / Cilt: 43 - Sayı: 6

Strong and Direct Correlation in Heart Failure Between B-Lines and NT-ProBNP Levels

Kalp Yetersizliğinde B-çizgileri ile NT-ProBNP Düzeyleri Arasında Güçlü ve Direkt Korelasyon

Pages
640–647
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

NT-proBNP levels, the NHYA classification, and lung ultrasound can be used as a tool in the emergency department for a faster diagnosis and decision-making in lung congestion.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of the study was to evaluate the compliance of the number of B-lines on focused lung ultrasound with the clinical heart failure classification of the New York Heart Association (NYHA) and NT-proBNP levels in the emergency department.
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Key Findings & Data:Patients over 18 years of age complaining of shortness of breath or heart failure diagnosis between January 2016 and July 2016.
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Conclusion & Impact:NT-proBNP levels, the NHYA classification, and lung ultrasound can be used as a tool in the emergency department for a faster diagnosis and decision-making in lung congestion.
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:kalp yetersizliği · NT-proBNP · B-çizgileri

Abstract

The aim of the study was to evaluate the compliance of the number of B-lines on focused lung ultrasound with the clinical heart failure classification of the New York Heart Association (NYHA) and NT-proBNP levels in the emergency department. This prospective study was conducted in a tertiary university hospital emergency department. Patients over 18 years of age complaining of shortness of breath or heart failure diagnosis between January 2016 and July 2016. The number of B-lines according to the BLUE point regions was measured. Correlations between the clinical heart failure stage, NT-proBNP level and number of B-lines on ultrasonography were analyzed. Of the 143 patients, 92 (64.3%) were male and 51 (35.7%) were female. The median age was 73.00 (66.00-79.00). There was a very strong correlation between the number of B-lines and NYHA stages for each region (r > 0.85 for all variables; p <0.001 for all). There was also a strong and direct correlation between the number of B-lines and the NT-proBNP levels for each region (r > 0.70; p <0.001). Regarding the shortness of breath numerical score (r > 0.45; p <0.001), there was an inverse relationship with ejection fraction (EF). The relationship between the EF and BLUE points was moderate, but negative and significant (p <0.001). NT-proBNP levels, the NHYA classification, and lung ultrasound can be used as a tool in the emergency department for a faster diagnosis and decision-making in lung congestion.

Özet

Çalışmanın amacı, odaklanmış akciğer ultrasonu üzerindeki B-çizgilerinin sayısının, New York Kalp Derneği'nin (NYHA) klinik kalp yetmezliği sınıflaması ve acil serviste NT-proBNP düzeyleriyle ilişkisini değerlendirmekti. Bu ileriye dönük çalışma, bir üçüncü basamak üniversite hastanesinin acil servisinde gerçekleştirildi. Ocak 2016 ile Temmuz 2016 tarihleri arasında nefes darlığı yakınması veya kalp yetmezliği tanısı olan 18 yaş üstü hastalar çalışmaya alındı. Hastaların BLUE protokolünde belirtilen bölgelere göre B çizgisi sayısı ölçüldü. Klinik kalp yetmezliği evresi, NT-proBNP düzeyi ve akciğer ultrasonografisindeki B-çizgisi sayısı arasındaki ilişkiler analiz edildi. Toplam 143 hastanın 92'si (% 64,3) erkek, 51'i (% 35,7) kadındı. Ortanca yaş 73,00 (66,00-79,00) idi. Her bölge için B çizgilerinin sayısı ve NYHA aşamaları arasında çok güçlü bir korelasyon vardı (tüm değişkenler için r >0.85; tümü için p <0.001). Ayrıca her bölge için B çizgilerinin sayısı ile NT-proBNP seviyeleri arasında güçlü ve doğrudan bir korelasyon vardı (r> 0.70; p <0.001). Nefes darlığı sayısal skoru (r> 0.45; p <0.001) ile ejeksiyon fraksiyonu (EF) arasında ters bir ilişki vardı. EF ve BLUE noktaları arasındaki ilişki orta düzeyde, ancak negatif ve anlamlıydı (p <0.001). NT-proBNP seviyeleri, NHYA sınıflandırması ve akciğer ultrasonu, acil serviste akciğer konjesyonunda daha hızlı tanı ve karar verme için bir araç olarak kullanılabilir.

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Cite This Article

ÇAĞLAYAN, T., DOLGUN, H., ACAR, N., ÖZAKIN, E., KAYA, F., ÇANAKÇI, M. E., ARSLAN, E. (2022). Strong and Direct Correlation in Heart Failure Between B-Lines and NT-ProBNP Levels. Osmangazi Tıp Dergisi, Cilt: 43 - Sayı: 6, 640–647. https://ajindex.com/articles/586074

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References (11)

  1. Gheorghiade M, Filippatos G, De Luca L, Burnett J. Congestion in acute heart failure syndromes: an essential target of evaluation and treatment. Am J Med 2006;119:S3-10
  2. Lichtenstein DA, Meziere GA. Relevance of lung ultrasound in the diagnosis of acute respiratory failure: the BLUE protocol. Chest 2008;134:117-25
  3. Jambrik Z, Monti S, Coppola V, Agricola E, Mottola G, Miniati M, et al. Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water. Am J Cardiol 2004;93:1265-70
  4. Agricola E, Bove T, Oppizzi M, Marino G, Zangrillo A, Margonato A, et al. “Ultrasound comet-tail images”: a marker of pulmonary edema: a comparative study with wedge pressure and extravascular lung water. Chest 2005;127:1690-5
  5. Agricola E, Picano E, Oppizzi M, Pisani M, Meris A, Fragasso G, et al. Assessment of stress-induced pulmonary interstitial edema by chest ultrasound during exercise echocardiography and its correlation with left ventricular function. J Am Soc Echocardiogr 2006;19:457-63
  6. Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, et al.; ESC Scientific Document Group. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 2016;18:891-975
  7. Felker GM, Hasselblad V, Hernandez AF, O'Connor CM. Biomarker-guided therapy in chronic heart failure: a meta-analysis of randomized controlled trials. Am Heart J 2009;158:422-30
  8. Januzzi JL Jr, Peacock WF, Maisel AS, Chae CU, Jesse RL, Baggish AL, et al. Measurement of the interleukin family member ST2 in patients with acute dyspnea: results from the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) study. J Am Coll Cardiol 2007;50:607-13
  9. Maisel AS, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, et al.; Breathing Not Properly Multinational Study Investigators. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med 2002;347:161-7
  10. Sachdeva A, Horwich TB, Fonarow GC. Comparison of usefulness of each of five predictors of mortality and urgent transplantation in patients with advanced heart failure. Am J Cardiol 2010;106:830-5
  11. Januzzi JL Jr, Camargo CA, Anwaruddin S, Baggish AL, Chen AA, Krauser DG, et