Objective: The aim of this study was to investigate the effects of estrogen or exercise or estrogen-exercise combination on oxidant damage and histopathological and functional changes observed in kidney and liver of rats with surgical menopause.
📌 3 Key Takeaways
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Objective & Hypothesis:Objective: The aim of this study was to investigate the effects of estrogen or exercise or estrogen-exercise combination on oxidant damage and histopathological and functional changes observed in kidney and liver of rats with surgical menopause.
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Key Findings & Data:Objective: The aim of this study was to investigate the effects of estrogen or exercise or estrogen-exercise combination on oxidant damage and histopathological and functional changes observed in kidney and liver of rats with surgical menopause.
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Conclusion & Impact:Objective: The aim of this study was to investigate the effects of estrogen or exercise or estrogen-exercise combination on oxidant damage and histopathological and functional changes observed in kidney and liver of rats with surgical menopause.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Egzersiz · menapoz · oksidan hasar
Abstract
Objective: The aim of this study was to investigate the effects of estrogen or exercise or estrogen-exercise combination on oxidant damage and histopathological and functional changes observed in kidney and liver of rats with surgical menopause.
Özet
Amaç: Bu çalışmanın amacı cerrahi olarak menopoz oluşturulan sıçanların böbrek ve karaciğerlerinde gözlenen histopatolojik ve fonksiyonel değişiklikleri ve östrojen veya egzersizin ya da östrojen-egzersiz kombinasyonunun oksidan hasar üzerine etkilerini araştırmaktır.
YEĞEN, B., TAMER, S. A., LEVENT, N., YÜKSEL, M., ERCAN, F., YILDIRIM, A. (2022). Beneficial Effects of Exercise and Estrogen in Maintaining Oxidant/Antioxidant Balance in the Liver and Kidney Tissues of Rats with Ovariectomy. Online Türk Sağlık Bilimleri Dergisi, Cilt: 7 - Sayı: 3, 460–467. https://ajindex.com/articles/585420
Kuller LH, Meilahn EN, Cauley JA, Gutai JP, Matthews KA. Epidemiologic studies of menopause: changes in risk factors and disease. Exp Gerontol. 1994;29(3-4):495-509.
Santo Signorelli S, Neri S, Sciacchitano S, et al. Behaviour of some indicators of oxidative stress in postmenopausal and fertile women. Maturitas. 2006;53(1):77-82. Sánchez-Rodríguez MA, Zacarías-Flores M, Arronte-Rosales A, Correa-Muñoz E, Mendoza-Núñez VM. Menopause as risk factor for oxidative stress. Menopause. 2012;19(3):361-367.
Şen E, Saruhan A. Menopoz ve hormon replasman tedavisi ile ilgili kanıta dayalı çalışmalar. Sosyal Politika Çalışmaları Dergisi. 2010;20(20):45-52.
Miller VT, LaRosa J, Barnabei V, et al. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women: the postmenopausal estrogen/progestin interventions (PEPI) trial. Jama. 1995;273(3):199-208.
Pradhan AD, Manson JE, Rossouw JE, et al. Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational study. Jama. 2002;288(8):980-987.
Siddiqui N, Rahman S, Mia A, Shamsuzzaman A. Evaluation of hormone replacement therapy. Mymensingh Med J. 2005;14(2):212-218.
Orri JC, Hughes EM, Mistry DG, Scala AH. Is Vigorous Exercise Training Superior to Moderate for CVD Risk after Menopause? Sports Med Int Open. 2017;1(5):E166-E171. Radák Z, Young Chung H, Naito H, et al. Age‐associated increases in oxidative stress and nuclear transcription factor κB activation are attenuated in rat liver by regular exercise. FASEB J. 2004;18(6):749-750. Souza CS, de Sousa Oliveira BS, Viana GN, et al. Preventive effect of exercise training on diabetic kidney disease in ovariectomized rats with type 1 diabetes. Exp Biol Med. 2019;244(9):758-769.
Nakajima D, Kim C-S, Oh T-W, et al. Suppressive effects of genistein dosage and resistance exercise on bone loss in ovariectomized rats. J Physiol Anthropol Appl Human Sci. 2001;20(5):285-291.
Babayev H, Arabaci-Tamer S, Yildirim A, et al. Sleeve gastrectomy–induced endocrine changes in the remnant stomachs of premenopausal and postmenopausal rats: role of the estrogen receptors. Surg Obes Relat Dis. 2021;17(1):193-207.
Arabacı Tamer S, Koyuncuoğlu T, Karagöz Köroğlu A, Akakın D, Yüksel M, Yeğen BÇ. Nesfatin-1 ameliorates oxidative brain damage and memory impairment in rats induced with a single acute epileptic seizure. Life Sci. 2022;294:120376. Fischer V, Haffner-Lun