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Journals / Okmeydanı Tıp Dergisi / 2018 / Cilt: 34 - Sayı: 2

Evaluation of Nephrolithiasis Risk Factors in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Single Center Experience

Otozomal Dominant Polikistik Böbrek Hastalarında Nefrolitiazis Risk Faktörlerinin Değerlendirmesi: Tek Merkez Deneyimi

Burhan COŞKUN
Ayşegül ORUÇ
Onur KAYGISIZ
Alparslan ERSOY
Abdülmecit YILDIZ
Hakan KILIÇARSLAN
Yakup KORDAN
Cemil Cihad GEDİK
Pages
87–91
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

History of frequent urinary tract infections(UTIs), the presence of liver cyst and gross hematuriawere found to be associated with the presence of kidneystones.Conclusion: According to our findings nephrolithiasisshould be kept in mind in ADPKD patients with liver cyst,hematuria, and recurrent UTIs.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Autosomal Dominant Polycystic Kidney Disease(ADPKD) is the most common hereditary kidney diseaseand nephrolithiasis is frequent among ADPKD patientscompared with general population.
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Key Findings & Data:In this study, we aimedto review the factors associated with the development ofkidney stones in ADPKD patients.Material and Methods: A total of 118 ADPKD patientswere retrospectively evaluated.
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Conclusion & Impact:History of frequent urinary tract infections(UTIs), the presence of liver cyst and gross hematuriawere found to be associated with the presence of kidneystones.Conclusion: According to our findings nephrolithiasisshould be kept in mind in ADPKD patients with liver cyst,hematuria, and recurrent UTIs.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Autosomal Dominant Polycystic Kidney Disease(ADPKD) is the most common hereditary kidney diseaseand nephrolithiasis is frequent among ADPKD patientscompared with general population. In this study, we aimedto review the factors associated with the development ofkidney stones in ADPKD patients.Material and Methods: A total of 118 ADPKD patientswere retrospectively evaluated. Demographic characteristics,serum biochemistry, and clinical features were comparedin stone formers and non-stone formers.Results: Twenty-eight patients (23.7%) were diagnosedwith kidney stones. History of frequent urinary tract infections(UTIs), the presence of liver cyst and gross hematuriawere found to be associated with the presence of kidneystones.Conclusion: According to our findings nephrolithiasisshould be kept in mind in ADPKD patients with liver cyst,hematuria, and recurrent UTIs.

Özet

Amaç: Otozomal Dominant Polikistik Böbrek (ODPKB) Hastalığı, en sık görülen kalıtsal böbrek hastalığıdır ve nefrolitiyaz genel popülasyonla karşılaştırıldığında bu hastalarda daha sıktır. Çalışmamızda, ODPKB hastalarında böbrek taşı gelişimi ile ilişkili faktörleri gözden geçirmeyi amaçladık. Gereç ve Yöntem: Toplam 118 ODPKB hastası geriye dönük olarak değerlendirildi. Taş oluşturanlar ve taş oluşturmayanlar arasında demografik özellikler, serum biyokimyası ve klinik özellikler karşılaştırıldı. Bulgular: Yirmi sekiz hastada (%23,7) böbrek taşı tespit edildi. Tekrarlayan idrar yolu enfeksiyonu (İYE) öyküsü, karaciğer kisti varlığı ve gros hematüri böbrek taş varlığı ile ilişkili bulunmuştur. Sonuç: Bulgularımıza göre karaciğer kisti, hematüri ve tekrarlayan İYE’li ODPKB hastalarında nefrolitiyaz olabileceği akılda tutulmalıdır.

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Cite This Article

COŞKUN, B., ORUÇ, A., KAYGISIZ, O., ERSOY, A., YILDIZ, A., KILIÇARSLAN, H., KORDAN, Y., GEDİK, C. C. (2022). Evaluation of Nephrolithiasis Risk Factors in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Single Center Experience. Okmeydanı Tıp Dergisi, Cilt: 34 - Sayı: 2, 87–91. https://ajindex.com/articles/584974

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