Journals / Namık Kemal Tıp Dergisi / 2022 / Cilt: 10 - Sayı: 2

Evaluation of the Relationship Between Polypharmacy and Malnutrition in Diabetic Elderly

Diyabetik Yaşlılarda Polifarmasi ve Malnütrisyon İlişkisinin Değerlendirilmesi

Pages
199–205
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A positive correlation was found between the number of drugs and HbA1c, and a negative correlation with the MNA-SF score (r=0.792, p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases in older adults.
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Key Findings & Data:With advancing age, polypharmacy and protein- energy malnutrition associated with chronic diseases can be seen frequently in T2DM patients due to metabolic causes and may adversely affect the prognosis.
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Conclusion & Impact:A positive correlation was found between the number of drugs and HbA1c, and a negative correlation with the MNA-SF score (r=0.792, p
🔬Design:Research Article
📍Scope:2021 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases in older adults. With advancing age, polypharmacy and protein- energy malnutrition associated with chronic diseases can be seen frequently in T2DM patients due to metabolic causes and may adversely affect the prognosis. In this study, it was aimed to evaluate the relationship between polypharmacy and malnutrition in T2DM patients. Materials and Methods: Three hundred and twenty-one patients aged 65 years and over, diagnosed with T2DM and receiving oral anti-diabetic drug therapy, who applied to the Internal Medicine and Geriatrics outpatient clinic between February and November 2021, were included in the study. The data of the patients were obtained retrospectively from their medical files. The use of 5 or more drugs was considered as polypharmacy. Mini Nutritional Assessment-short form (MNA-SF) was used for nutritional status assessment. Results: The median number of concomitant medications used in patients followed up with the diagnosis of T2DM was 5. Polypharmacy was found in 209 (65.1%) patients, and severe polypharmacy was found in 21 (6.5%) patients. Malnutrition was found in 43 (20.6%) patients with polypharmacy, while 17 (80.1%) of 21 patients with severe polypharmacy had malnutrition. A positive correlation was found between the number of drugs and HbA1c, and a negative correlation with the MNA-SF score (r=0.792, p

Özet

Amaç: Tip 2 diabetes mellitus (T2DM), yaşlı yetişkinlerde sık rastlanan kronik hastalıklardandır. İlerleyen yaşla birlikte kronik hastalıklarla ilişkili polifarmasi ve protein-enerji malnütrisyonu metabolik nedenlere bağlı olarak T2DM hastalarında sık görülebilir ve prognozu olumsuz etkileyebilir. Bu çalışmada T2DM hastalarında polifarmasi ve malnütrisyon ilişkisinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Şubat-Kasım 2021 tarihleri arasında İç Hastalıkları ve Geriatri Polikliniği’ne başvuran, 65 yaş ve üzeri T2DM tanısı olan ve oral anti-diyabetik ilaç tedavisi alan 321 hasta çalışmaya dahil edildi. Hastaların verileri tıbbi dosyalarından retrospektif olarak elde edildi. Beş ve üzeri ilaç kullanımı polifarmasi olarak kabul edildi. Beslenme durum değerlendirmesinde Mini Nutrisyonel değerlendirme- kısa form (MNA-SF) kullanıldı. Bulgular: T2DM tanısı ile takip edilen hastalarda eşzamanlı kullanılan ilaçların medyan sayısı 5 idi. Hastaların 209’unda (%65,1) polifarmasi, 21’inde (%6,5) ise şiddetli polifarmasi saptandı. Polifarmasisi olan hastaların 43’ünde (%20,6) malnütrisyon saptanırken şiddetli polifarmasisi olan 21 hastanın 17’sinde (%80,1) malnütrisyon vardı. İlaç sayısı ile HbA1c arasında pozitif, MNA-SF puanı ile negatif korelasyon saptandı (sırasıyla r=0,792, p

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Cite This Article

YAKARYILMAZ, F. D., ERAYDIN, A. (2022). Evaluation of the Relationship Between Polypharmacy and Malnutrition in Diabetic Elderly. Namık Kemal Tıp Dergisi, Cilt: 10 - Sayı: 2, 199–205. https://ajindex.com/articles/584005

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