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Journals / Middle East Journal of Science / 2021 / Cilt: 7 - Sayı: 2

THREE MSA TOOLS ANALYSIS IN DNA AND PROTEIN DATASETS

Fırat AŞIR
Tuğcan KORAK
Özgür ÖZTÜRK
Pages
89–99
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results showed that MAFFT may be more useful to align DNA and protein sequences than the other two tools.

📌 3 Key Takeaways

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Objective & Hypothesis:Multiple sequence alignment (MSA) is the alignment of three or more sequences of DNA,RNA, and protein.
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Key Findings & Data:In this article three MSA tools; CLUSTALW, SAGA, and MAFFT were used to analyze fivedatasets BALiBASE_R9, DIRMBASE, SABmark, DNABali, and ProteinBali.
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Conclusion & Impact:The results showed that MAFFT may be more useful to align DNA and protein sequences than the other two tools.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Multiple sequence alignment (MSA) is the alignment of three or more sequences of DNA,RNA, and protein. MSA is used to construct phylogenetic trees and to compare evolutionaryrelationships between sequences analyzing similarities and dissimilarities. A variety of multiplesequence alignment tools are available, each using different methods and parameters to alignsequences. In this article three MSA tools; CLUSTALW, SAGA, and MAFFT were used to analyze fivedatasets BALiBASE_R9, DIRMBASE, SABmark, DNABali, and ProteinBali. The results showed that MAFFT may be more useful to align DNA and protein sequences than the other two tools.

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Cite This Article

AŞIR, F., KORAK, T., ÖZTÜRK, Ö. (2022). THREE MSA TOOLS ANALYSIS IN DNA AND PROTEIN DATASETS. Middle East Journal of Science, Cilt: 7 - Sayı: 2, 89–99. https://ajindex.com/articles/580423

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