Journals / Medeniyet Medical Journal / 2017 / Cilt: 32 - Sayı: 2

The effects of dexamethasone vs low doses of propofol infusion on postoperative nausea and vomiting in tympanoplasty surgery: A randomized, placebo-controlled, double-blinded study

Timpanoplasti cerrahisinde postoperatif bulantı ve kusmaya deksametazon ile düşük doz propofol infüzyonunun etkilerinin karşılaştırılması: Randomize, plasebo-kontrollü, çift kör çalışma

Pages
85–90
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Differences were observed between the groups in hours 0-2 and 2-8 in terms of verbal descriptive scale values for postoperative nausea and vo- miting (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This prospective study investigated the effects of dexamethaso- ne and low-dose propofol infusion on postoperative nausea and vomiting in 90 patients undergoing tympanoplasty.
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Key Findings & Data:The dexa- methasone group (Group D) received 8 mg dexamethasone and the control group (Group C) 2 ml saline 15 min before the end of surgery, while the propofol group (Group P) received ıntrave- nous propofol infusion at a dose of 20 mcg/kg/min throughout surgery following induction of anaesthesia.
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Conclusion & Impact:Differences were observed between the groups in hours 0-2 and 2-8 in terms of verbal descriptive scale values for postoperative nausea and vo- miting (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This prospective study investigated the effects of dexamethaso- ne and low-dose propofol infusion on postoperative nausea and vomiting in 90 patients undergoing tympanoplasty. The dexa- methasone group (Group D) received 8 mg dexamethasone and the control group (Group C) 2 ml saline 15 min before the end of surgery, while the propofol group (Group P) received ıntrave- nous propofol infusion at a dose of 20 mcg/kg/min throughout surgery following induction of anaesthesia. Incidence rates and severity of nausea-vomiting and antiemetic requirements were recorded throughout the first postoperative 24 hours. Between hours 0 and 2, any incidence of postoperative nausea and vo- miting was not observed in 23 (76.7%) patients in Group P, 17 (56.7%) in Group D and 8 (26.7%) in Group C. Differences were observed between the groups in hours 0-2 and 2-8 in terms of verbal descriptive scale values for postoperative nausea and vo- miting (p

Özet

Bu prospektif çalışmayla, timpanoplasti uygulanan 90 hastada postoperatif bulantı ve kusma üzerine deksametazon ve düşük doz propofol infüzyonunun etkileri araştırıldı. Ameliyat bitimin- den 15 dk. önce deksametazon grubuna (Grup D) 8 mg deksame- tazon ve kontrol grubuna (Grup C) 2 ml salin yapılırken, propofol grubuna (Grup P), anestezi indüksiyonu sonrasında ameliyat bo- yunca 20 mcg/kg/dk. propofol intravenöz infüzyonu yapılmıştır. Postoperatif ilk 24 saat boyunca bulantı-kusma ve antiemetik gereksinimlerinin insidans ve şiddeti kaydedildi. Sıfır-iki saatlik periyotta, Grup P’de 23 (%76,7) hastada, Grup D’de 17 (%56,7) ve Grup C’de 8 hastada (%26,7) postoperatif bulantı ve kusma görülmedi. Gruplar arasında postoperatif bulantı ve kusma için sözel tanımlayıcı ölçek değerleri açısından 0-2 ve 2-8 saatlik sü- reler arasında farklar gözlemlendi (sırasıyla p

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Cite This Article

ARSLAN, Z., BİNGÖL, F., BİNGÖL, B. Ö., ÖZMEN, Ö. (2022). The effects of dexamethasone vs low doses of propofol infusion on postoperative nausea and vomiting in tympanoplasty surgery: A randomized, placebo-controlled, double-blinded study. Medeniyet Medical Journal, Cilt: 32 - Sayı: 2, 85–90. https://ajindex.com/articles/579314

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