Journals / Medeniyet Medical Journal / 2018 / Cilt: 33 - Sayı: 1

A 70-year-old patient with seronegative lupus nephritis: Rare case

Yetmiş yaşında seronegatif lupus nefritli hasta: Nadir olgu

Pages
54–56
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case wasunusual type of SLE due to multiple reasons namely the patientwas an elderly woman, with isolated lupus nephritis and negative serology including ANA negativity

📌 3 Key Takeaways

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Objective & Hypothesis:Systemic lupus erythematosus (SLE) is an autoimmune diseaseknown to be associated with various kinds of autoantibodiessuch as Antinuclear antibodies (ANA).
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Key Findings & Data:We report a 70-yearold female who presented with massive edema and 10-gram/dayproteinuria.
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Conclusion & Impact:This case wasunusual type of SLE due to multiple reasons namely the patientwas an elderly woman, with isolated lupus nephritis and negative serology including ANA negativity
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune diseaseknown to be associated with various kinds of autoantibodiessuch as Antinuclear antibodies (ANA). ANA is found to be positivein most of the SLE patients. In fact, ANA positivity in serum isone of the diagnostic criteria of SLE. However, a minority of SLEpatients may present with ANA negativity. We report a 70-yearold female who presented with massive edema and 10-gram/dayproteinuria. Her serum antibodies for SLE were all negative andthe renal biopsy showed a class V lupus nephritis. This case wasunusual type of SLE due to multiple reasons namely the patientwas an elderly woman, with isolated lupus nephritis and negative serology including ANA negativity

Özet

Sistemik lupus eritematozus (SLE), antinükleer antikor (ANA) gibi çeşitli antikorlar ile ilişkili olduğu bilinen otoimmun bir hastalıktır. SLE hastalarının çoğunda ANA pozitif olarak bulunmaktadır. Aslında ANA pozitifliği SLE’nin tanı kriterlerinden biridir. Fakat, SLE hastalarının çok az bir kısmı ANA negatifliği gösterebilir. Masif ödemi ve 10 g/gün proteinürisi olan 70 yaşındaki kadın hastayı rapor yayınladık. Hastanın SLE serum antikorlarının hepsi negatifti ve böbrek biyopsisi lupus nefriti sınıf 5 olduğunu gösterdi. Bu olgu, birden fazla nedenden dolayı SLE’nin alışılmadık bir şeklidir. Bu hasta yaşlı bir kadın olup, izole lupus nefriti ve ANA negativiteyi de içeren negatif seroloji ile beraberdi.

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Cite This Article

UYSAL, S. P., DAĞEL, T., BÜLBÜL, M. C., MERAM, E., ERBİL, D., ÖNAL, E. M. (2022). A 70-year-old patient with seronegative lupus nephritis: Rare case. Medeniyet Medical Journal, Cilt: 33 - Sayı: 1, 54–56. https://ajindex.com/articles/579295

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