Journals / Medeniyet Medical Journal / 2019 / Cilt: 34 - Sayı: 3

Evaluation of Clinicopathologic Features of Patients Diagnosed with Atypical Glandula Cells in Cervical Cytology

Servikal Sitolojide Atipik Glandüler Hücre Tanısı Konan Hastaların Klinikopatolojik Özelliklerinin Değerlendirilmesi

Pages
284–289
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Therefore patients diagnosed with atypical glandular cell in cervicovaginal smear should be carefully evaluated with all clinical features.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In our study we aimed to evaluate the clinicopathologic features of patients diagnosed with atyipcal glandular cells on cervical cytology.
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Key Findings & Data:Method: The records of 9375 patients who were examined in the gynecology outpatient clinic between 2010 and 2018 and underwent cervicovaginal smear were retrospectively reviewed.
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Conclusion & Impact:Therefore patients diagnosed with atypical glandular cell in cervicovaginal smear should be carefully evaluated with all clinical features.
🔬Design:Review & Systematic Survey
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In our study we aimed to evaluate the clinicopathologic features of patients diagnosed with atyipcal glandular cells on cervical cytology. Method: The records of 9375 patients who were examined in the gynecology outpatient clinic between 2010 and 2018 and underwent cervicovaginal smear were retrospectively reviewed. Seventy-three (0.8%) patients were diagnosed as atypical glandular cells. Colposcopic examination, cervical biopsy, endocervical and endometrial curettage were performed in patients diagnosed with atypical glandular cells. Age, gravida, parity, systemic diseases and clinicopathological features of the patients were examined and recorded Results: Cervical and endometrial abnormal histological findings were detected in 26 (35.6%) of 73 patients with atypical glandular cells. Of these 26 patients, 14 (19.1%) had cervical intraepithelial lesions, 3 (4.1%) had endometrial hyperplasia and 9 (12.3%) had invasive cancer. Five (6.8%) of the 9 patients with the diagnosis of invasive cancer had adenocarcinoma (endocervical and endometrial), in 3 (4.1%) patients cervical squamous carcinoma, and in 1 patient. endocervical lymphoma was observed.The majority of cancers detected in our study were in the age group of 50 years and older. Conclusion: Invasive cancer is seen in 12.3% of the patients diagnosed with atypical glandular cells, and most of these patients are 50 years or older. Therefore patients diagnosed with atypical glandular cell in cervicovaginal smear should be carefully evaluated with all clinical features.

Özet

Amaç: Çalışmamızda servikovajinal smear sonrası atipik glandüler hücre tanısı konan hastaların klinikopatolojik özelliklerini değerlendirmeyi amaçladık. Yöntem: Kadın hastalıkları polikliniğinde 2010-2018 yılları arasında muayene edilen ve servikovajinal smear yapılan 9375 hastanın kayıtları retrospektif olarak incelendi. Yetmiş üç (% 0,8) hastaya atipik glanduler hücreler tanısı kondu. Atipik glandüler hücreler tanısı konulan hastalarda kolposkopik muayene, servikal biyopsi, endoservikal ve endometriyal küretaj yapıldı. Hastaların yaş, gravida, parite, sistemik hastalıklar ve klinikopatolojik özellikleri incelendi ve kaydedildi Bulgular: Atipik glandüler hücreli 73 hastanın 26’sında (%35,6) servikal ve endometrial anormal histolojik bulgular saptandı. Bu 26 hastanın 14’ünde (%19,1) servikal intraepitelyal lezyon, 3’ünde (%4,1) endometrial hiperplazi, 9’unda (%12,3) invaziv kanser mevcuttu. İnvaziv kanser tanısı alan 9 hastanın beşinde (%6,8) adenokarsinom (endoservikal ve endometrial), 3’ünde (%4,1) servikal skuamöz karsinom gözlendi. Bir hastada endoservikal lenfoma izlendi. Çalışmamızda tespit edilen kanserlerin büyük çoğunluğu 50 yaş ve üstü yaş grubundaydı. Sonuç: Atipik glanduler hücre tanısı konan hastaların %12.3 de invaziv kanser görülmektedir ve bu hastaların çoğunun yaşı 50 yaş ve üzeridir. Bu nedenle servikovaginal smear nedeniyle atipik glandüler hücre tanısı konan hastalar tüm klinik özelliklerle dikkatlice değerlendirilmelidir.

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Cite This Article

TOSUN, O. A., CAKMAK, Y., COMERT, D. K., OGE, T., SOZEN, I. (2022). Evaluation of Clinicopathologic Features of Patients Diagnosed with Atypical Glandula Cells in Cervical Cytology. Medeniyet Medical Journal, Cilt: 34 - Sayı: 3, 284–289. https://ajindex.com/articles/579251

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