Journals / Kulak Burun Boğaz İhtisas Dergisi / 2000 / Cilt: 7 - Sayı: 3

Local and regional recurrence in early glottic carcinomas

Erken evre glottik tümörlerde lokal ve bölgesel rekürens

Pages
205–209
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It was concluded that open surgery performed in appropriate cases yielded very successful oncological outcome in early glottic carcinoma.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: To evaluate local and regional recurrence rates and survival in early glottic carcinoma (stage I and stage II).
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Key Findings & Data:Patients and Methods: Forty-five patients (43 males, 2 females; mean age 56 years; range 35-73 years) who underwent surgery for stage I or II glottic squamous cell carcinoma were evaluated.
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Conclusion & Impact:Conclusion: It was concluded that open surgery performed in appropriate cases yielded very successful oncological outcome in early glottic carcinoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: To evaluate local and regional recurrence rates and survival in early glottic carcinoma (stage I and stage II). Patients and Methods: Forty-five patients (43 males, 2 females; mean age 56 years; range 35-73 years) who underwent surgery for stage I or II glottic squamous cell carcinoma were evaluated. The patients were followed-up for a mean duration of 22 months (range 6-54 months). Results: Of 45 patients, %73.3 had T1N0 and %26.7 had T2N0 cancers. Surgery included laryngofissure cordectomy (n=31), vertical laryngectomy (n=9), and frontolateral laryngectomy (n=5). Primary local and/or regional recurrence occurred in six patients (13%) within the first twelve months. Six patients required salvage surgery. Mean survival obtained with primary and salvage surgery was 91% (n=41). Conclusion: It was concluded that open surgery performed in appropriate cases yielded very successful oncological outcome in early glottic carcinoma.

Özet

Amaç: Erken evre (evre I ve evre II) glottik kanserlerde lokal ve bölgesel rekürens oranını ve sağkalımı incelemek. Hastalar ve Yöntemler: Kliniğimizde tanı ve tedavisi yapılan evre I ve II glottik yassı epitel hücreli kanserli 45 hasta (43 erkek, 2 kadın; ort. yaş 56; dağılım 35-73) değerlendirildi. Olguların ortalama takip süresi 22 ay (dağılım 6-54 ay) idi. Bulgular: Olguların %73.3'ü T1N0, %26.7'si ise T2N0 kanserli idi. Otuz bir hastada larengofissür+kordektomi, dokuz hastada vertikal larenjektomi, beş hastada frontolateral larenjektomi uygulandı. İlk 12 ay içinde 45 olgunun altısında (%13) primer lokal ve/veya bölgesel rekürens gelişti. Altı hastada kurtarma cerrahisine başvuruldu. Kurtarma cerrahisi ile birlikte elde edilen ortalama sağkalım %91 (n=41) bulundu. Sonuç: Açık cerrahi ile tedavinin doğru endikasyon konmuş olgularda onkolojik açıdan çok başarılı olduğu sonucuna varıldı.

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Cite This Article

ÜNAL, M., ERDAMAR, B., SÜOĞLU, Y., SUNAY, T., ŞİRİN, M., KATIRCIOĞLU, O. S., KARATAY, M. C., ÇÖLHAN, İ. (2022). Local and regional recurrence in early glottic carcinomas. Kulak Burun Boğaz İhtisas Dergisi, Cilt: 7 - Sayı: 3, 205–209. https://ajindex.com/articles/576478

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