Journals / Koşuyolu Heart Journal / 2021 / Cilt: 24 - Sayı: 3

Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion

Orta-Ciddi Perikardiyal Efüzyon Nedeniyle Perikardiyosentez Yapılan Hastaların Klinik Özellikleri ve Hastane İçi Mortaliteyi Etkileyen Faktörler

Pages
221–228
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Receiving antithrombotic therapy and having a non-idiopathic and non-infectious etiology may be predictors of in-hospital mortality.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: The aim of this study was to determine the primary etiology of pericardial effusion in patients undergoing percutaneous pericardiocentesis.
📊
Key Findings & Data:Patients and Methods: A retrospective analysis was made of the clinical and laboratory features of 268 patients who underwent pericardiocentesis due to moderate to severe pericardial effusion between January 2009 and March 2020.
💡
Conclusion & Impact:Receiving antithrombotic therapy and having a non-idiopathic and non-infectious etiology may be predictors of in-hospital mortality.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: The aim of this study was to determine the primary etiology of pericardial effusion in patients undergoing percutaneous pericardiocentesis. Possible in-hospital mortality related predictors were also investigated. Patients and Methods: A retrospective analysis was made of the clinical and laboratory features of 268 patients who underwent pericardiocentesis due to moderate to severe pericardial effusion between January 2009 and March 2020. Results: The patients comprised 57.5% males and 42.5% females with a mean age of 62.3 ± 15.4 years. Cardiac compression was detected in 220 (82.1%) patients, of which 208 (77.6%) were clinically tamponade and 12 (4.5%) were asymptomatic cardiac compression. The most common symptom was dyspnea (58.6%) and 10.8% of patients were asymptomatic. Pericardial fluid was exudate in 235 (87.7%) patients. The most common causes were malignancy (37.3%) followed by idiopathic (22.1%) and iatrogenic (12.7%) causes. The patients with asymptomatic cardiac compression were more likely to have malignant effusion than those with other etiologies (p= 0.001). In-hospital mortality developed in 37 (13.8%) patients. The independent predictors of in-hospital mortality were determined as follows; etiology other than infectious or idiopathic (OR= 3.447; 95% CI= 1.266, 9.386; p= 0.015), and receiving antithrombotic therapy (OR= 2.306; 95% CI= 1.078, 4.932; p= 0.031). Conclusion: Malignancy is the most common cause of moderate to severe pericardial effusions. The detection of cardiac compression in asymptomatic patients may be an important indicator of malignancy. Receiving antithrombotic therapy and having a non-idiopathic and non-infectious etiology may be predictors of in-hospital mortality.

Özet

Giriş: Bu çalışmanın amacı, perkütan perikardiyosentez yapılan hastalarda perikardiyal efüzyonun birincil etiyolojisini belirlemektir. Ayrıca hastane içi mortaliteyle ilişkili olası öngördürücüler de araştırılmıştır. Hastalar ve Yöntem: Ocak 2009-Mart 2020 tarihleri arasında orta-şiddetli perikardiyal efüzyon nedeniyle perikardiyosentez yapılan 268 hastanın klinik ve laboratuvar özellikleri geriye dönük analiz edildi. Bulgular: Hastaların %57.5’i erkek ve %42.5’i kadın olup, ortalama yaş 62.3 ± 15.4 yıldır. Hastaların 220 (%82.1)’sinde kardiyak bası saptanmıştır. Bunlardan 208 (%77.6)’i klinik olarak tamponad, 12 (%4.5)’si asemptomatik kardiyak basıydı. En sık semptom dispneydi (%58.6) ve hastaların %10.8’i asemptomatikti. Hastaların 235 (%87.7)’i perikardiyal sıvı eksüda vasfındaydı. En sık nedenler, malignite (%37.3) ardından idiyopatik (%22.1) ve iyatrojenikti (%12.7). Asemptomatik kardiyak basısı bulunan hastaların malign efüzyon olma olasılığı diğer etiyolojilere göre daha fazlaydı (p= 0.001). Hastaların 37 (%13.8)’sinde hastane içi mortalite gelişmişti. Enfeksiyöz veya idiyopatik dışı etiyoloji (OR= 3.447; %95 GA= 1.266, 9.386; p= 0.015) ve antitrombotik tedavi almak (OR= 2.306; %95 CI= 1.078, 4.932; p= 0.031) hastane içi mortalite için bağımsız öngördürücüler olarak saptanmıştır. Sonuç: Malignite, orta-ciddi perikardiyal efüzyonların en sık nedenidir. Asemptomatik hastalarda kardiyak basının saptanması malignitenin önemli bir göstergesi olabilir. Antitrombotik tedavi almak ve idiyopatik ve enfeksiyöz olmayan bir etiyolojiye sahip olmak hastane içi mortalite için öngördürücüler olabilir.

🔖

Cite This Article

ŞENÖZ, O., EMREN, V., EMREN, Z. Y., ERSEÇGİN, A., YURDAM, F. S., NAZLI, C. (2022). Clinical Features and Factors Affecting In-Hospital Mortality of Patients Who Underwent Pericardiocentesis Due To Moderate To Severe Pericardial Effusion. Koşuyolu Heart Journal, Cilt: 24 - Sayı: 3, 221–228. https://ajindex.com/articles/575894

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Sagrista-Sauleda J, Merce J, Permanyer-Miralda G, Soler-Soler J. Clinical clues to the causes of large pericardial effusions. Am J Med 2000
  2. [Crossref] 2. Van Trigt P, Douglas J, Smith PK, Campbel PT, Wall TC, Kenney RT, et al. A prospective trial of subxiphoid pericardiotomy in the diagnosis and treatment oflarge pericardial effusion. A follow-up report. Ann Surg 1993
  3. [Crossref] 3. Levy PY, Corey R, Berger P, Habib G, Bonnet JL, Levy S, et al. Etiologic diagnosis of 204 pericardial effusions. Medicine 2003
  4. [Crossref] 4. Corey GR, Campbell PT, Van Trigt P, Kenny TR, O’Connor CM, Sheikh KH, et al. Etiology of large pericardial effusions. Am J Med 1993
  5. [Crossref] 5. Colombo A, Olson HG, Egan J, Gardin JM. Etiology and prognostic implications of a large pericardial effusion in men. Clin Cardiol 1988
  6. [Crossref] 6. Tsang TS, Enriquez-Sarano M, Freeman WK, Barnes ME, Sinak LJ, Gersh BJ, et al. Consecutive 1127 therapeutic echocardiographically guided pericardiocenteses: clinical profile, practice patterns, and outcomes spanning 21 years. Mayo Clin Proc 2002
  7. [Crossref] 7. Vaitkus PT, Herrmann HC, LeWinter MM. Treatment of malignant pericardial effusion. JAMA 1994
  8. [Crossref] 8. Meyers DG, Meyers RE, Prendergast TW. The usefulness of diagnostic tests on pericardial fluid. Chest 1997
  9. [Crossref] 9. Fowler NO. Cardiac tamponade. A clinical or an echocardiographic diagnosis? Circulation 1993
  10. [Crossref] 10. Perez-Casares A, Cesar S, Brunet-Garcia L, Sanches-de-Toledo J. Echocardiographic evaluation of pericardial effusion and cardiac tamponade. Front Pediatr 2017
  11. [Crossref] 11. Merce J, Sagrista-Sauleda J, Permanyer-Miralda G, Evangelista A, Soler- Soler J. Correlation between clinical and Doppler echocardiographic findings in patients with moderate and large pericardial effusion: implications for the diagnosis of cardiac tamponade. Am Heart J 1999
  12. [Crossref] 12. Levine MJ, Lorell BH, Diver DJ, Come PC. Implications of echocardiographically assisted diagnosis of pericardial tamponade in contemporary medical patients: detection before hemodynamic embarrassment. J Am Coll Cardiol 1991
  13. [Crossref] 13. Ziskind AA, Pearce AG, Lemmon CC, Burstein S, Gimple LW, Herrmann CH, et al. Percutaneous balloon pericardiotomy for the treatment of cardiac tamponade and large pericardial effusions: description of technique and report of the first 50 cases.