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Journals / Kocaeli Tıp Dergisi / 2019 / Cilt: 8 - Sayı: 3

Neutrophil-Lymphocyte Ratio is Valuable in Predicting the Pathology Result in the Patients with Renal Mass > 4 cm Prior to the Partial Nephrectomy

Nötrofil-Lenfosit Oranı, Parsiyel Nefrektomi Öncesinde 4 cm'den Büyük Renal Kitlesi Olan Hastaların Patoloji Sonucunu Tahmin Etmekte Faydalıdır

Erdem TOPRAK
Efe ÖNEN
Sinan AVCI
Sedat ÖNER
Volkan ÇAĞLAYAN
Murat ŞAMBEL
Metin KILIÇ
Pages
22–27
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies must be performed to certify theefficacy of NLR.

📌 3 Key Takeaways

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Objective & Hypothesis:INTRODUCTION: To assess the efficacy of neutrophillymphocyte ratio (NLR) in predicting the pathology results of renal masses prior to partial nephrectomy (PN).METHODS: The data of 76 patients who underwent PNbetween March 2012 and March 2018 was evaluated.
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Key Findings & Data:Patientswere grouped according to pathology results (malign groupbenign group), tumor stage (T1a-T1b) and tumor grade (Grade1-Grade2-Grade3) and mass size (≤4 cm->4 cm).RESULTS: Benign group was consisted of 17 patients andmalign group was of 59 patients.
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Conclusion & Impact:Further studies must be performed to certify theefficacy of NLR.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

INTRODUCTION: To assess the efficacy of neutrophillymphocyte ratio (NLR) in predicting the pathology results of renal masses prior to partial nephrectomy (PN).METHODS: The data of 76 patients who underwent PNbetween March 2012 and March 2018 was evaluated. Patientswere grouped according to pathology results (malign groupbenign group), tumor stage (T1a-T1b) and tumor grade (Grade1-Grade2-Grade3) and mass size (≤4 cm->4 cm).RESULTS: Benign group was consisted of 17 patients andmalign group was of 59 patients. No statistically significantdifference was found when preoperative NLR of benign andmalign groups were compared (p=0.113). When malign groupwas divided into 2 groups according to tumor stage (T1a-T1b),NLR of T1b group was significantly higher than benign group and T1a group (p=0.007 and p4 cm malign renal masses (p=0.035). The cut-off value to predict malignancy was 2.31 with 65% specificity and 50% sensitivity.DISCUSSION and CONCLUSION: NLR is a valuable parameter at predicting pathology result in patients with renal masses >4 cm. Higher NLR value was associated high grade tumors. Further studies must be performed to certify theefficacy of NLR.

Özet

GİRİŞ ve AMAÇ: Nötrofil-lenfosit oranının (NLR) parsiyel nefrektomi (PN) öncesi renal kitlelerin patoloji sonuçlarının öngörülmesindeki etkinliğini değerlendirmek.YÖNTEM ve GEREÇLER: Mart 2012 ve Mart 2018 tarihleri arasında PN yapılan 76 hastanın verileri değerlendirildi. Hastalar patoloji sonuçlarına (malign grup benign grup), tümör evresine (T1a-T1b) ve tümör derecesine (Grade 1-Grade2-Grade3) ve kitle boyutuna ( 4 cm) göre gruplandı.BULGULAR: Benign grup 17 hastadan, malign grup 59 hastadan oluşmaktaydı. Benign ve malign grupların preoperatif NLR'leri karşılaştırıldığında istatistiksel olarak anlamlı bir fark bulunmadı (p = 0.113). Malign grup tümör evresine göre (T1a-T1b) 2 gruba ayrıldığında, T1b grubunun NLR değeri benign grup ve T1a grubundan anlamlı olarak yüksekti (sırasıyla p= 0.007 ve p

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Cite This Article

TOPRAK, E., ÖNEN, E., AVCI, S., ÖNER, S., ÇAĞLAYAN, V., ŞAMBEL, M., KILIÇ, M. (2022). Neutrophil-Lymphocyte Ratio is Valuable in Predicting the Pathology Result in the Patients with Renal Mass > 4 cm Prior to the Partial Nephrectomy. Kocaeli Tıp Dergisi, Cilt: 8 - Sayı: 3, 22–27. https://ajindex.com/articles/574802

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