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Journals / Kocaeli Tıp Dergisi / 2019 / Cilt: 8 - Sayı: 1

Epicardial adipose tissue thickness is associated with disease severity in patients with newly- diagnosed ankylosing spondylitis

Yeni tanı konulan ankilozan spondilitli hastalarda epikardiyal yağ dokusu kalınlığı hastalık ciddiyeti ile ilişkilisi

Halim YILMAZ
Mehmet Sertaç APAYDIN
Halil Ekrem AKKURT
ZAFER BÜYÜKTERZİ
Pages
97–103
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

EAT thickness was significantly increased in AS patients when compared to the controls (p

📌 3 Key Takeaways

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Objective & Hypothesis:INTRODUCTION: Cardiovascular (CV) disease is a welldescribed co-morbidity in patients with inflammatory arthritis.
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Key Findings & Data:Age- and gendermatched control subjects who fulfilled the inclusion criteria were also included in the study.RESULTS: 100 subjects [40.00 (34.25- 48.00) years, 65% male] were included in the study.
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Conclusion & Impact:EAT thickness was significantly increased in AS patients when compared to the controls (p
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

INTRODUCTION: Cardiovascular (CV) disease is a welldescribed co-morbidity in patients with inflammatory arthritis. Epicardial adipose tissue (EAT) contributes to the development and progression of coronary atherosclerosis independent of traditional CV risk factors. In this study, we aimed to investigate whether EAT thickness determined by transthoracic echocardiography (TTE) in newly-diagnosed ankylosing spondilitis (AS) patients is associated with AS severity.METHODS: In this retrospective study, TTE reports of newlydiagnosed AS patients were reviewed. Age- and gendermatched control subjects who fulfilled the inclusion criteria were also included in the study.RESULTS: 100 subjects [40.00 (34.25- 48.00) years, 65% male] were included in the study. EAT thickness was significantly increased in AS patients when compared to the controls (p

Özet

GİRİŞ ve AMAÇ: İnflamatuar hastalıklarda kardiyovasküler hastalıkların eşlik ettiği daha önceki çalışmalarda tanımlanmıştır. Geleneksel risk faktörlerinin yanı sıra epikardiyal yağ dokusu koroner ateroskleroz gelişim ve ilerlemesine katkıda bulunur. Bu çalışmada yeni tanı konulan ankilozan spondilitli (AS) hastalarda transtorasik ekokardiyografi ile ölçülen epikardiyal yağ doksu kalınlığı ile hastalık ciddeti arasındaki ilişkiyi araştırmayı amaçladık. YÖNTEM ve GEREÇLER: Bu retrospektif çalışmada yeni tanı konulan ankilozan spondilitli hastaların transtorasik ekokardiyografi raporları tarandı. Ayrıca katılım kriterlerini sağlayan yaş ve cinsiyet eşlenik bireyler control grubu olarak çalışmaya dahil edildi. BULGULAR: 100 birey [40.00 (34.25- 48.00) yıl, 65% erkek] çalışmaya dahil edildi. Epikardiyal yağ dokusu kalınlığı AS’li hastalarda control grubuna göre artmıştı (p

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Cite This Article

YILMAZ, H., APAYDIN, M. S., AKKURT, H. E., BÜYÜKTERZİ, Z. (2022). Epicardial adipose tissue thickness is associated with disease severity in patients with newly- diagnosed ankylosing spondylitis. Kocaeli Tıp Dergisi, Cilt: 8 - Sayı: 1, 97–103. https://ajindex.com/articles/574797

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References (13)

  1. Lindqvist E, Eberhardt K. Mortality in rheumatoid arthritis patients with disease onset in the 1980s. Ann Rheum Dis. 1999;58(1):11-4
  2. Maradit-Kremers H, Crowson CS, Nicola PJ, Ballman KV, Roger VL, Jacobsen SJ, et al. Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a populationbased cohort study. Arthritis and rheumatism. 2005;52(2):402-11
  3. Maradit-Kremers H, Nicola PJ, Crowson CS, Ballman KV, Gabriel SE. Cardiovascular death in rheumatoid arthritis: a population-based study. Arthritis and rheumatism. 2005;52(3):722-32
  4. Gabriel SE. Cardiovascular morbidity and mortality in rheumatoid arthritis. The American journal of medicine. 2008;121(10 Suppl 1):S9-14
  5. Gensler LS. Axial spondyloarthritis: the heart of the matter. Clin Rheumatol. 2015;34(6):995-8
  6. Mason JC, Libby P. Cardiovascular disease in patients with chronic inflammation: mechanisms underlying premature cardiovascular events in rheumatologic conditions. European heart journal. 2015;36(8):482-9c
  7. Rabkin SW. Epicardial fat: properties, function and relationship to obesity. Obes Rev. 2007;8(3):253-61
  8. Pierdomenico SD, Pierdomenico AM, Cuccurullo F, Iacobellis G. Meta-analysis of the relation of echocardiographic epicardial adipose tissue thickness and the metabolic syndrome. The American journal of cardiology. 2013;111(1):73-8
  9. Iacobellis G, Ribaudo MC, Assael F, Vecci E, Tiberti C, Zappaterreno A, et al. Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk. J Clin Endocrinol Metab. 2003;88(11):5163-8
  10. Iacobellis G, Leonetti F. Epicardial adipose tissue and insulin resistance in obese subjects. The Journal of clinical endocrinology and metabolism. 2005;90(11):6300-2
  11. Mahabadi AA, Lehmann N, Kalsch H, Robens T, Bauer M, Dykun I, et al. Association of epicardial adipose tissue with progression of coronary artery calcification is more pronounced in the early phase of atherosclerosis: results from the Heinz Nixdorf recall study. JACC Cardiovasc Imaging. 2014;7(9):909-16
  12. Mahabadi AA, Berg MH, Lehmann N, Kalsch H, Bauer M, Kara K, et al. Association of epicardial fat with cardiovascular risk factors and incident myocardial infarction in the general population: the Heinz Nixdorf Recall Study. Journal of the American College of Cardiology. 2013;61(13):1388-95
  13. Sade LE, Eroglu S, Bozbas H, Ozbicer S, Hayran M, Haberal A, et