Journals / Klinik Psikofarmakoloji Bülteni / 2002 / Cilt: 12 - Sayı: 4

Dementia with lewy bodies: A case report

Lewy cisimcikli demans: Olgu sunumu

Pages
186–190
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we report a DLB case with depressive symptoms and discuss the diagnosis and different diagnosis under the light of current literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Following the description of Lewy body spectrum disorders by Kosaka in 1980, dementia with Lewy bodies (DLB) which was considered as a rare cause of dementia before, is much more frequently recognized.
📊
Key Findings & Data:The prevalence of DLB has been estimated between 10-26 % by using clinical diagnosis consensus criteria.
💡
Conclusion & Impact:Here we report a DLB case with depressive symptoms and discuss the diagnosis and different diagnosis under the light of current literature.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Following the description of Lewy body spectrum disorders by Kosaka in 1980, dementia with Lewy bodies (DLB) which was considered as a rare cause of dementia before, is much more frequently recognized. DLB can be considered as being a member of spectrum of disorders which also includes Alzheimer's disease and Parkinson's disease. The prevalence of DLB has been estimated between 10-26 % by using clinical diagnosis consensus criteria. DLB presents with cognitive, motor and psychiatric symptoms and most of the patients are elderly. Depression, anxiety and psychotic symptoms which are characterized by hallucinations and persecutory delusions are very common and the clinical presentation routinely includes one of the psychiatric symptoms. The diagnosis and management of DLB must be recognized by psychiatrists by the fact that its prevalence is estimated to be very common among the psychiatrically ill elderly patients. Here we report a DLB case with depressive symptoms and discuss the diagnosis and different diagnosis under the light of current literature.

Özet

Kosaka tarafından 1980 yılında tanımlanmış olan Lewy cisimcikli demans (DLB), Alzheimer hastalığı ve Parkinson hastalığının patolojik spektrumunu paylaşan, motor ve psikiyatrik belirtilerle giden demansiyel bir hastalıktır. Bu yazı, son yıllarda hakkında çok fazla yayın olan bu hastalığı, bir olgu nedeniyle ele almayı ve ilgili literatür ışığında tartışmayı amaçlamıştır. Prevalansı %10-26 arasında bildirilen DLB olgularının çoğu yaşlıdır. Varsanılar ve perseküsyon sanrılarıyla kendini gösteren belirli psikotik tablolar, depresyon ve anksiyete bu olgularda sıktır ve bu bulgulardan en az biri klinik tabloda bulunur. Psikiyatrik tablolar nedeniyle tedavi edilen yaşlı olguların önemli bir bölümünün DLB olduğu tahmin edilmektedir. Bu açıdan psikiyatri uzmanları tarafından tanınması ve tedavi seçeneklerinin bilinmesi önemlidir. Bu yazının konusu depresif yakınmalarla başvuran bir olgunun DLB tanısı ve ayırıcı tanısı yönünden tartışılmasıdır. Tanı ve tedavisi belirgin güçlükler içermekle birlikte görülme sıklığı düşünüldüğünde, bu hastalık hakkındaki bilgilerimizi arttırıp tanı araçlarımızı geliştirmenin gerekliliği ortaya çıkmaktadır.

🔖

Cite This Article

ATALAY, N. D., GÜLPEK, D., KESEBİR, S., BAYRAKTAR, E. (2022). Dementia with lewy bodies: A case report. Klinik Psikofarmakoloji Bülteni, Cilt: 12 - Sayı: 4, 186–190. https://ajindex.com/articles/574509

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Albin RL, Minoshima S, D'amato CJ. Fluoro-deoxyglucose positron emission tomography in diffuse Lewy body disease. Neurology l996;47:462-466
  2. Burke WJ, Pfeiffer RF, McComb RD. Neuroleptic sensitivity to clozapine in- dementia with Lewy bodies. J Neuropsychiatry din NeurosciV1998; 10:227-229.
  3. Roland RP, Merritt's Textbook of Neurology. 9th Ed, Baltimore: Waverly Company 1995:677-685
  4. Byrne EJ, Lennox G, Lowe J, Godwin-Austen RB. Diffuse Lewy body disease: clinical features in 15 cases. J Neurol Neurosurg Psychiatry 1989;52:709-717
  5. Gibb WRG, Esiri MM, Lees AJ. Clinical and pathological features of diffuse cortical Lewy body disease. Brain 1987;110:1131-1153
  6. Hansen LA, Salmon D, Galasko D. The Lewy body variant Alzheimer's disease: a clinical pathological entity. Neurology 1990; 40:1-8
  7. Gomez-Tortosa E, Ingraham AO, Inzarry MC. Dementia with Lewy bodies. J Am Geriatr Soc 1998;46:1449-1458
  8. Hashimoto M, Kitagaki H, Imamura T. Medial temporal and whole-brain atrophy in dementia with Lewy bodies. A volumetric MRI study. Neurology 1998;51:357-362
  9. McKeith IG, Galasko D, Kosaka K. Clinical dagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology 1996;47:1113-1124
  10. Lennox GG. Dementia with Lewy bodies. In: The Dementias. Eds: JH Growdon, MR Rossor, R Katzman, M Roth. First Ed, St Louis, Butterworth Heinemann 1998;67-79
  11. Mega MS, Mastermann DL, Benson F. Dementia with Lewy bodies: reliability and validity of clinical and pathologic criteria. Neurology 1996;47:1403-1409
  12. Ala TA, Yang KH, Sung JH, Frey WH 2nd. Hallucinations and signs of parkinsonism help distinguish patients with dementia and cortical Lewy bodies from patients with Alzheimer's disease at presentation; a clinicopathological study. J Neurol Neurosurg Psychiatry 1997;62:16-21
  13. Ballard c, Piggott M, Johnson M, Cairns N, Perry R, McKeiht I, Janos E, O'Brien J, Holmes C, Perry E. Delusions associated with elevated muscarinebinding in dementia Lewy bodies. Ann Neurol 2000;48:868-876
  14. DuBois JM. Recent attacks on brain death: do they merit a reconsideration of our current policies? Health Care Ethics USA. 1998;6:4-5
  15. Connor DJ, Salmon DP, Sandy TJ, Galasko D, Hansen LA, Thai LJ. Cognitive profiles of autopsy-confirmed Lewy body variant vs pure Alzheimer disease. Arch Neurol 1998;55:994-1000
  16. Olinchney JM, Galasko D, Salmon DP, Hofstetter CR, Hansen LA,Katzman R, Thai LJ. Cognitive decline is fast