Journals / Klinik Psikofarmakoloji Bülteni / 2006 / Cilt: 16 - Sayı: 2

Psychotic disorder due to vitamine B12 defiency

B12 Vitamini eksikliğine bağlı psikotik bozukluk

Pages
109–113
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

With this case, we would like to draw attention to association between B12 deficiency and nonfunctional psychosis and emphasize the importance of assessment of B12 levels in patients presenting with a psychotic episode

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Vitamin B12 deficiency may present itself with neurological, haematological, gastrointestinal and psychiatric symptoms.
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Key Findings & Data:There are limited number of psychotic cases reported due to B12 avitaminosis in current literature.
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Conclusion & Impact:With this case, we would like to draw attention to association between B12 deficiency and nonfunctional psychosis and emphasize the importance of assessment of B12 levels in patients presenting with a psychotic episode
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Vitamin B12 deficiency may present itself with neurological, haematological, gastrointestinal and psychiatric symptoms. There are limited number of psychotic cases reported due to B12 avitaminosis in current literature. This vitamine interacts with neurotransmitters on molecular level and its deficiency causes psychiatric disorders by disturbing the neurotransmitter balance. Using antipsychotics only, do not improve psychotic symptoms without vitamine B12 replacement treatment. Vitamine B12 replacement results in complete recovery in a very short time. We present here an 18 year-old female patient with irritability, odd behaviours and speech, poor concentration, social isolation and fatigue. She was hospitalised with the diagnosis of psychotic disorder. The examination of serum vitamine B12 levels were found to be very low. Her psychotic symptoms such as disorganized speech, persecutive thought content improved dramatically by B12 vitamin replacement treatment. With this case, we would like to draw attention to association between B12 deficiency and nonfunctional psychosis and emphasize the importance of assessment of B12 levels in patients presenting with a psychotic episode

Özet

B12 vitamini eksikliği nörolojik,hematolojik, gastrointestinal ve psikiyatrik belirtilerle karşımıza çıkabilmektedir. B12 avitaminozuna bağlı psikotik olgular literatürde sınırlı sayıda yer almaktadır. Bu vitamin moleküler düzeyde nörotransmitterlerle etkileşim gösterir ve eksikliğinde nörotransmitter dengesini bozarak psikiyatrik hastalığa yol açabilir. Psikotik semptomlar vitamini yerine koyma tedavisi uygulanmadıkça, sadece antipsikotik kullanımıyla düzelmemektedir. B12 vitamini ile birlikte semptomlar kısa zamanda iyileşme gösterirler. B12 eksikliğinin tedavisinde yerine koyma tedavisi uygulanır. Olgumuz 18 yaşında, bekâr, bayan hasta. Sinirlilik, garip davranış ve konuşma, unutkanlık, içe kapanma, güçsüzlük yakınmaları ile polikliniğe bağvurdu ve psikotik bozukluk tanısı ile yatışı yapıldı. Tetkiklerinde B12 vitamin düzeyinin düşük seviyede gelmesi üzerine, B12 vitamini yerine koyma tedavisi sonucu psikotik semptomlarında dramatik düzelme gözlendi. Bu olguyu sunarak psikiyatri dışı hastalıklara bağlı psikozlara dikkat çekmeyi ve psikotik atakla gelen bir hastada B12 vitamin düzeyi bakılması gerekliliğini hatırlatmayı amaçladık.

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Cite This Article

TELCİ, Ş., OKAY, İ. T., DANKI, D., DİLBAZ, N. (2022). Psychotic disorder due to vitamine B12 defiency. Klinik Psikofarmakoloji Bülteni, Cilt: 16 - Sayı: 2, 109–113. https://ajindex.com/articles/574391

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