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Journals / Klinik Psikofarmakoloji Bülteni / 2012 / Cilt: 22 - Sayı: 1

Obsessif kompulsif bozukluk hastalarında artmış plazma nesfatin-1 düzeyi

Increased plasma nesfatin-1 levels in patients with obsessive compulsive disorder

Mustafa ARI
Yesim CAN
Yasin BEZ
Oktay Hasan ÖZTÜRK
Süleyman OKTAR
Pages
5–9
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The observed difference in plasma nesfatin-1 levels between two groups was statistically significant (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To determine and compare the plasma nesfatin-1 (a satiety peptide) levels of patients with obsessive compulsive disorder (OCD) and healthy control subjects.
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Key Findings & Data:Method: Plasma nesfatin-1 levels of 31 patients with OCD (18 females, 13 males) and 28 healthy control subjects (16 females and 12 males) similar to the study group in terms of weight, age, and gender were measured in this study.
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Conclusion & Impact:The observed difference in plasma nesfatin-1 levels between two groups was statistically significant (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To determine and compare the plasma nesfatin-1 (a satiety peptide) levels of patients with obsessive compulsive disorder (OCD) and healthy control subjects. Method: Plasma nesfatin-1 levels of 31 patients with OCD (18 females, 13 males) and 28 healthy control subjects (16 females and 12 males) similar to the study group in terms of weight, age, and gender were measured in this study. Severity of obsessions and compulsions both in OCD patients and control subjects were determined by using Yale-Brown Obsessive Compulsive Scale (Y-BOCS). ELISA method was used to measure plasma nesfatin-1 levels. Results: Median plasma nesfatin-1 levels in patients with OCD and healthy control subjects were 4.61 ng/ml (min-max: 1.28-8.11) and 2.0 ng/ml (min-max: 0.11-4.98) respectively. The observed difference in plasma nesfatin-1 levels between two groups was statistically significant (p

Özet

Amaç: Bu yazıda, obsesif kompulsif bozukluk (OKB) tanısı olan hastalarda ve sağlıklı kontrollerde plazma nesfatin-1 (bir tokluk peptidi) düzeylerinin tespit edilmesi ve karşılaş- tırılması amaçlanmıştır. Yöntem: OKB tanısı olan 31 hastanın (18 kadın, 13 erkek) ve ağırlık, yaş ve cinsiyet açısından benzer nitelikte 28 sağlıklı bireyin (16 kadın, 12 erkek) plazma nesfatin-1 düzeyi ölçülmüş- tür. OKB hasta grubunda ve kontrol grubunda obsesyon ve kompulsiyonların şiddeti Yale-Brown Obsesyon Kompulsiyon Ölçeği (Y-BOKÖ) kullanılarak elde edilmiştir. Plazma nesfatin-1 düzeyi ölçümü için ELİSA yöntemi kullanılmıştır. Bulgular: OKB tanısı olan hastalarda ve kontrol grubunda ortanca plazma nesfatin-1 düzeylerinin sırasıyla 4.61 ng/ ml (min-max: 1.28-8.11) ve 2.0 ng/ml (min-max: 0.11- 4.98) olduğu bulunmuştur. Gruplar arasında plazma nesfa- tin-1 düzeyi açısından gözlemlenen fark istatistiksel olarak anlamlı düzeydedir (p

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Cite This Article

ARI, M., CAN, Y., BEZ, Y., ÖZTÜRK, O. H., OKTAR, S. (2022). Obsessif kompulsif bozukluk hastalarında artmış plazma nesfatin-1 düzeyi. Klinik Psikofarmakoloji Bülteni, Cilt: 22 - Sayı: 1, 5–9. https://ajindex.com/articles/574142

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