SavedAdd your journal

Journals / Klinik Psikofarmakoloji Bülteni / 2012 / Cilt: 22 - Sayı: 4

Bipolar bozuklukta lateralizasyonun motor ve mental hıza etkisi

Effect of lateralization on motor and mental speed in bipolar disorder

Murat İlhan ATAGÜN
Cahit KESKİNKILIÇ
Özlem Devrim BALABAN
Dilek YEŞİLBAŞ
Cüneyt EVREN
Pages
297–306
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patients performed poorer than the controls on the MOCA (p=0.049), peg-board (right and left, p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The correspondence between the motor and mood regulation systems may shed light on the physiopathology of mood disorders.
📊
Key Findings & Data:In this study we have investigated the effects of lateralization on cognitive performance as well as motor and mental speed in bipolar disorder.
💡
Conclusion & Impact:The patients performed poorer than the controls on the MOCA (p=0.049), peg-board (right and left, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The correspondence between the motor and mood regulation systems may shed light on the physiopathology of mood disorders. Handedness is a reliable proxy measure for cerebral lateralization for right handed subjects. In this study we have investigated the effects of lateralization on cognitive performance as well as motor and mental speed in bipolar disorder. Methods: Sixty-eight euthymic bipolar patients (mean age: 33.66±6.38, 33 female), and 65 healthy subjects (mean age: 33.65+7.11, 27 females) were enrolled. Participants with medical or psychiatric comorbidities were excluded. The Montreal Cognitive Assessment (MOCA), finger-tapping, peg-board test, Adult Memory and Information Processing battery (AMIPB), Edinburgh Handedness Inventory and reaction time tests were the measures utilized in our study. Results: The groups were similar in terms of age, gender and education. The bipolar patients were more lateralized than the controls (p=0.027), whereas eye and foot lateralization did not differ between the groups. The patients performed poorer than the controls on the MOCA (p=0.049), peg-board (right and left, p

Özet

Amaç: Motor ve duygudurum düzenleyici sistemlerin arasındaki ilişki duygudurum bozukluklarının fizyopatolojilerinin anlaşılmasına ışık tutabilir. El tercihi, sağ elini kullanan bireylerde serebral lateralizasyonun güvenilir bir ölçüsüdür. Bu araştırmada lateralizasyonun bilişsel performansın yanı sıra motor ve mental hız üzerine olan etkilerinin incelenmesi amaçlanmıştır. Yöntemler: Araştırmaya 68 ötimik bipolar hasta (ortalama yaş: 33.66±6.38, 33 kadın) ve 65 sağlıklı katılımcı (ortalama yaş: 33.65+7.11, 27 kadın) alındı. Tıbbi veya psikiyatrik hastalığı olanlar çalışmaya alınmadı. Montreal Bilişsel Değerlendirme (MOCA), parmak-tıklama, Peg-board, Yetişkin bellek ve bilgi işleme hızı bataryası (AMIPB), Edinburgh el tercihi envanteri ve reaksiyon zamanı testleri uygulandı. Bulgular: Gruplar yaş, cinsiyet ve eğitim durumu bakımından benzerdi. Bipolar hastalar kontrollere göre daha lateralize idiler (p=0.027). Göz ve ayak lateralizasyonu açısından fark bulunmadı. Hastalar kontrollere göre MOCA (p=0.049), Peg-board (her iki el p

🔖

Cite This Article

ATAGÜN, M. İ., KESKİNKILIÇ, C., BALABAN, Ö. D., YEŞİLBAŞ, D., EVREN, C. (2022). Bipolar bozuklukta lateralizasyonun motor ve mental hıza etkisi. Klinik Psikofarmakoloji Bülteni, Cilt: 22 - Sayı: 4, 297–306. https://ajindex.com/articles/574109

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Nowicka A, Tacikowski P. Transcallosal transfer of information and functional asymmetry of the human brain. Laterality 2011; 16(1):35-74
  2. Crow TJ. Bipolar shifts as disorders of the bi-hemispheric integration of language: Implications for the genetic origins of the psychotic continuum. In: Marneros A, Angst J, editors. Bipolar disorders: 100 years after manic depressive insanity. Dordrecht: Kluwer; 2000; p.335-48
  3. Bilder RM, Wu H, Bogerts B, Ashtari M, Robinson D, Woerner M, et al. Cerebral volume asymmetries in schizophrenia and mood disorders: A quantitative magnetic resonance imaging study. Int J Psychophysiol 1999;34(3):199-205
  4. Bellani M, Marzi CA, Savazzi S, Perlini C, Cerruti S, Ferro A, et al. Laterality effects in schizophrenia and bipolar disorder. Exp Brain Res 2010;201(2):339-44
  5. Dragovic M, Hammond G. Handedness in schizophrenia: a quantitative review of evidence. Acta Psychiatr Scand 2005;111(6):410-9
  6. Caligiuri MP, Brown GG, Meloy MJ, Eyler LT, Kindermann SS, Eberson S, et al. A functional magnetic resonance imaging study of cortical asymmetry in bipolar disorder. Bipolar Disord. 2004; 6(3):183-96
  7. Goodwin FK, Jamison KR. Manic-Depressive Illness: Bipolar Disorders and Recurrent Depression, 2nd Edition. New York: Oxford University Press; 2007. p. 282-9
  8. Crow TJ. The ‘big bang’ theory of the origin of psychosis and the faculty of language. Schizophr Res 2008;102(1-3):31-52
  9. Reite M, Teale P, Rojas DC, Arciniegas D, Sheeder J. Bipolar disorder: anomalous brain asymmetry associated with psychosis. Am J Psychiatry 1999;156(8):1159-63
  10. Oribe N, Onitsuka T, Hirano S, Hirano Y, Maekawa T, Obayashi C,et al. Differentiation between bipolar disorder and schizophrenia revealed by neural oscillation to speech sounds: an MEG study. Bipolar Disord 2010;12(8):804-12
  11. Reite M, Teale P, Rojas DC, Reite E, Asherin R, Hernandez O. MEG auditory evoked fields suggest altered structural/functional asymmetry in primary but not secondary auditory cortex in bipolar disorder. Bipolar Disord 2009;11(4):371-81
  12. Innocenti GM, Ansermet F, Parnas J. Schizophrenia, neurodevelopment and corpus callosum. Mol Psychiatry 2003;8(3):261-74
  13. Arnone D, McIntosh AM, Chandra P, Ebmeier KP. Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder. Acta Psychiatr Scand 2008;118(5):357-62
  14. Arnone D, McIntosh AM, Tan GM, Ebmeier KP. Meta-analysis of magnetic resonance imaging studies of the corpus callo