Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2003 / Cilt: 14 - Sayı: 1

The effect of metronidazole and intraperitoneal lavage on the complications in secondary peritonitis cases

Sekonder peritonitlerde metronidazol ile intraperitoneal lavajın komplikasyonlar üzerine olan etkisi

Pages
8–10
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

On the contrary, 46 patients in the control group were received only systemic antibiotics, upon which wound site infection in 8 of patients (17%) and evisceration in 1 case (2%) occurred (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Postoperative intraabdominal abscess, brid ileus, evisceration and wound site infections constitute major problems for surgeons.
📊
Key Findings & Data:However, no study concerning the changes in complications and mortality upon intraabdominal use of antibiotics was performed in recent years. 92 consecutive patients operated in our clinic due to fecal or purulent peritonitis were categorized into two groups and observed.
💡
Conclusion & Impact:On the contrary, 46 patients in the control group were received only systemic antibiotics, upon which wound site infection in 8 of patients (17%) and evisceration in 1 case (2%) occurred (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Postoperative intraabdominal abscess, brid ileus, evisceration and wound site infections constitute major problems for surgeons. It is known that antibiotics administered parenterally and enterally can reduce these complications. However, no study concerning the changes in complications and mortality upon intraabdominal use of antibiotics was performed in recent years. 92 consecutive patients operated in our clinic due to fecal or purulent peritonitis were categorized into two groups and observed. Preoperative intraabdominal metronidazole and lavage was applied in addition to systemic antibiotics to 46 patients in the study group. Complications were observed only in 2 patients (4%) within this group. These consisted of wound site infection and evisceration. On the contrary, 46 patients in the control group were received only systemic antibiotics, upon which wound site infection in 8 of patients (17%) and evisceration in 1 case (2%) occurred (p

Özet

Postoperatif intraabdominal abse, brid ileus, eviserasyon ve yara yeri enfeksiyonları cerrahlar için büyük problemler oluşturmaktadır. Parenteral ve enteral uygulanan antibiyotiklerin bu komplikasyonlan azalttığı bilinmektedir. Ancak antibiyotiklerin intraperitoneal kullanımı ile komplikasyonlann ve mortalitenin değişimi ile ilgili bir çalışma son yularda yapılmamıştır. Kliniğimizde fekal ya da püriilan peritonit sebebi ile öpere edilen 92 ardışık hasta iki gruba ayrılarak incelenmiştir. Çalışma grubundaki 46 hastaya sistemik antibiyotiklerin yanı sıra peroperatif intraperitoneal metronidazol ile lavaj uygulanmıştır. Bu grupta sadece 2 (%4) hastada komplikasyon gözlenmiştir. Bunlar yara yeri enfeksiyonu ve eviserasyondur. Buna karşın kontrol grubundaki 46 hastaya sadece sistemik antibiyotik verilmiş olup, hastalarını 8'inde (% 17) yara yeri enfeksiyonu, l hastada (%2) eviserasyon oluşmuştur (p

🔖

Cite This Article

VURAL, S., TUNÇAY, E., MENTEŞ, C. V., ERDEMİR, A., ÇİNÇİN, T. G., DALKILIÇ, G. (2022). The effect of metronidazole and intraperitoneal lavage on the complications in secondary peritonitis cases. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 14 - Sayı: 1, 8–10. https://ajindex.com/articles/571575

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Withmann DH, Condon RE. Prophylaxis of postoperative infections. Infection 1991; 6(19) Suppl: 337
  2. Withmann DH. Intraabdominal infections: Pathophysiology and treatment. 1st edition, Mercel Dekker, New York, 1999: 8-9
  3. Fry DE, Garrison RN, Heitsch RC, et al. Determinants of death in patients with intraabdominal abscess. Surgery 1980; 88: 517-23
  4. Drusano GL, Warren JW, Saah AJ, et al. A prospective randomized controlled trial of cefoxitine versus clindamycine aminoglycoside in mixed anaerobic-aerobic infections. Surg Gynocol Obstet 1982; 154: 715-20
  5. Lennard ES, Minshew BH, Dellinger EP, et al. Stratified outcome comparison of clindamicin-gentamicin vs chloramphenicol-gentamisin for treatment of intraabdominal sepsis. Arch Surg 1985; 120(8): 889-91
  6. Mosdell DM, Morris DM, Voltura A, et al. Antibiotic treatment for surgical peritonitis. Ann Surg 1991; 214(5): 543-9
  7. Sauven P, Playfort M, Smith GMR, et al. Singel–dose antibiotic prophylaxis of abdominal surgical wound infection: A trial of preoperatif latamoxef against preoperative tetracycline lavage. J R Soc Med 1986; (79): 137-141
  8. Hersman MJ, Swift RI, Reilly DT, et al. Prospective comparative study of cefotetan with piperacillin for prophylaxis against infection in elective colorectal surgery. JR Coll Surg Edinb 1990; 35: 29-32
  9. McKenna JP, Currie DJ, McDonalds JA, et al. The use of continuous postoperative peritoneal lavage in the management of diffuse peritonitis. Surg Gynecol Obstet 1970; 130: 254-8
  10. Noon GP, Beal AC Jr, Jordan GL, et al. The clinical evaluation of peritoneal irrigation with antibiotic solution. Surgery 1967; 62: 73-8
  11. Dellinger EP, Wertz MJ, Meakins JL, et al. Surgical infection strafication system for intraabdominal infection. Multicenter trial. Arch Surg 1985; 120(1): 21-9
  12. Marx CG, Ritchie JK, Todd IP. Primary suture of the perineal wound following rectal excision for inflammatory bowel disease. Br J Surg 1978; 5(8): 560-4
  13. Ingham HR, Sisson PR, Tharagonnet D, et al. Inhibition of phagocytosis in vitro by obligate anaerobes. Lancet 1977; 2(8051): 1252-4
  14. Billing AG, Frohlich D, Konecny G, et al. Local serum application: Restoration of sufficent host defense in human peritonitis. Eur J Clin Invest 1994; 24(1): 28-35
  15. Fowler RA. Controlled trial of intraperitoneal cephaloridine administration in peritonitis. J Pediatr Surg 1975; 10(1): 43-50
  16. Browne MK, Stoller JL. Intraperitoneal noxythiolin in fecal peritonitis. Br J Surg 1970