Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2011 / Cilt: 22 - Sayı: 1

Follow-up and treatment of a severe tetanus case in the intensive care unit

Ciddi bir tetanoz olgusunun yoğun bakımda takip ve tedavisi

Pages
45–48
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In this report, we aimed to present the follow-up and treatment of a patient with severe tetanus in intensive care unit.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Tetanus is an acutely progressive, morbid disease that results from exposure to the exotoxins produced by Clostridium tetani.
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Key Findings & Data:The disease has an importance because of its high mortality, especially in patients older than 60 years.
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Conclusion & Impact:In this report, we aimed to present the follow-up and treatment of a patient with severe tetanus in intensive care unit.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Tetanus is an acutely progressive, morbid disease that results from exposure to the exotoxins produced by Clostridium tetani. The disease has an importance because of its high mortality, especially in patients older than 60 years. Respiratory failure is the most severe problem related to generalized tetanus. Mechanical ventilation is almost always mandatory for the therapy of respiratory insufficiency in patients with tetanus-developed airway obstruction. The patient presented herein was 65 years old and nonimmunized, and had generalized tetanus and respiratory failure. She was transported to intensive care unit following intubation. Mechanical ventilation was applied for 27 days to relieve autonomic dysfunction. Midazolam and magnesium were given for sedation, and when sedation was insufficient, neuromuscular block was administered. She was discharged at 38 days when respiratory and cardiac functions and hemodynamic parameters had resolved. In this report, we aimed to present the follow-up and treatment of a patient with severe tetanus in intensive care unit.

Özet

Tetanoz akut gelişen, ölümcül seyredebilen, Clostridium tetani’nin ürettiği ekzotoksinlerin neden olduğu bir hastalıktır. Özellikle 60 yaş üzerinde yüksek mortalitesi nedeniyle önem arz etmektedir. Solunum tutulumu jeneralize tetanozda görülen en ciddi sorundur. Hastalarda görülen solunum yetersizliği ve havayolu tıkanıklığı sıklıkla ventilatör desteğini gerektirmektedir. Olgumuz 65 yaşında uygun immünizasyonu olmayan, jeneralize tip tetanoz tanısıyla solunum yetmezliği gelişen bir olguydu. Entübe edilerek yoğun bakım ünitesine alındı. Otonomik disfonksiyonları düzelmesi için 27 gün mekanik ventilatör desteğinde tutuldu. Sedasyon için midazolam ve magnezyum infüzyonu uygulanan hastaya sedasyonun yetmediği durumda kas gevşetici verildi. Otuz sekizinci günde kardiyak, hemodinamik ve solunum fonksiyonları düzelmiş olarak taburcu edildi. Bu yazıda, hastanın yoğun bakımdaki takip ve tedavi süreci sunuldu.

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Cite This Article

ALATLI, İ., KUZUCUOĞLU, T., İTAL, İ. (2022). Follow-up and treatment of a severe tetanus case in the intensive care unit. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 22 - Sayı: 1, 45–48. https://ajindex.com/articles/571496

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References (10)

  1. Bleck TP. Clostridium tetani (Tetanus). In: Mandell GL, Bennet JE, Dolin R, editors. Mandell, Douglas, and Ben- nett’s Principles and Practice of Infectious Disease. 6th ed. Philadelphia: Elsevier, Churchill Livingstone; 2005. p. 2817-22
  2. Edlich RF, Hill LG, Mahler CA, Cox MJ, Becker DG, Horow- itz JH, et al. Management and prevention of tetanus. J Long Term Eff Med Implants 2003;13(3):139-54
  3. Cook TM, Protheroe RT, Handel JM. Tetanus: a review of the literature. Br J Anaesth 2001;87(3):477-87
  4. CDC Surveillance summaries-Tetanus, June 20, 2003. MMWR,2003:52,3
  5. Castro L, Gonçalves G, Catarino J. Reported cases of teta- nus in the North of Portugal (1993-2002). Missed oppor- tunities for vaccination. Acta Med Port 2004;17(3):225- 30
  6. Attygalle D, Rodrigo N. New trends in the management of tetanus. Expert Rev Anti Infect Ther 2004;2(1):73-84
  7. Salman C, Sekban N, Döşemeci L, Cengiz M, Yılmaz M, Ramazanoğlu A. Yoğun bakımımızda tetanoz: On yedi hastada tedavi, komplikasyonlar ve mortalit- enin değerlendirilmesi. Türk Anest Rean Der Dergisi 2007;35(3):200-8
  8. Rhee P, Nunley MK, Demetriades D, Velmahos G, Doucet JJ. Tetanus and trauma: a review and recommendations. J Trauma 2005;58(5):1082-8
  9. Attygalle D, Rodrigo N. Magnesium sulphate for control of spasms in severe tetanus. Can we avoid sedation and artificial ventilation? Anaesthesia 1997;52(10):956-62
  10. King WW, Cave DR. Use of esmolol to control autonomic instability of tetanus. Am J Med 1991;91(4):425-8