Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2012 / Cilt: 23 - Sayı: 1

A case with stevens-johnson syndrome after chemotherapy and radiotherapy

Kemoterapi ve radyoterapi sonrasında gelişen stevens-johnson sendromlu bir olgu

Pages
30–34
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patient developed erythema, bullae and occasional eroded areas that started at the site of radiation on the 34th day of radiotherapy and spread to the whole body, as well as hemorrhagic crusts and conjunctival hyperemia.

📌 3 Key Takeaways

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Objective & Hypothesis:Stevens-Johnson syndrome is a disease characterized by fever, purulent conjunctivitis, erosive stomatitis, and skin lesions with generalized exanthem.
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Key Findings & Data:Many factors including drugs, infectious agents, carcinomas, leukemias, and collagen tissue diseases are known to play a role in its etiology.
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Conclusion & Impact:The patient developed erythema, bullae and occasional eroded areas that started at the site of radiation on the 34th day of radiotherapy and spread to the whole body, as well as hemorrhagic crusts and conjunctival hyperemia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Stevens-Johnson syndrome is a disease characterized by fever, purulent conjunctivitis, erosive stomatitis, and skin lesions with generalized exanthem. Many factors including drugs, infectious agents, carcinomas, leukemias, and collagen tissue diseases are known to play a role in its etiology. Radiotherapy is one of the factors that rarely has a part in the etiology of this disease. However, it is not clear whether radiotherapy is an etiological factor in and of itself. We present a case who had been receiving radiotherapy concurrently with docetaxel and cisplatin chemotherapy for epidermoid carcinoma. The patient developed erythema, bullae and occasional eroded areas that started at the site of radiation on the 34th day of radiotherapy and spread to the whole body, as well as hemorrhagic crusts and conjunctival hyperemia.

Özet

Stevens-Johnson sendromu yüksek ateş, pürülan konjunktivit, eroziv stomatit ve jeneralize ekzantemli cilt lezyonları ile kendini gösteren bir hastalıktır. Etyolojide özellikle ilaçlar, enfeksiyon ajanları, karsinomlar, lösemiler ve kollajen doku hastalıkları gibi pek çok faktörün rol oynadığı bilinmektedir. Radyoterapi bu hastalığın etyolojisinde yer alan nadir nedenlerden biridir. Ancak radyoterapinin tek başına bir etken olup olmadığı konusu henüz daha aydınlatılmamıştır. Nazofarenks epidermoid karsinomu nedeniyle dosetaksel ve sisplatin kemoterapisi ile eş zamanlı radyoterapi alan ve radyoterapinin 34. gününde özellikle radyasyon uygulanan bölgede başlayarak tüm vücuda yayılan eritem, bül, yer yer erode alanlar ve hemorajik kurutlar, konjuktival hiperemi gelişen hastayı sunuyoruz.

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Cite This Article

OKUR, İ., ÇİÇEK, D., KÖKÇAM, İ., DERTLİOĞLU, B. S., İNCİ, R., ERTÜRKLER, E. (2022). A case with stevens-johnson syndrome after chemotherapy and radiotherapy. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 23 - Sayı: 1, 30–34. https://ajindex.com/articles/571464

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References (1)

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