Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2013 / Cilt: 24 - Sayı: 1

Mixed merkel cell carcinoma and squamous cell carcinoma: Case report

Mikst merkel hücreli karsinom ve skuamöz hücreli karsinom: Olgu sunumu

Pages
54–59
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this publication, we discuss a case of mixed Merkel cell carcinoma and squamous cell carcinoma in the context of the contemporary literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Merkel cell carcinoma, also known as small cell carcinoma of the skin, is a malignant cutaneous neuroendocrin tumor.
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Key Findings & Data:The diagnosis of this tumor is rare but it has high tendency for local recurrence, regional lymph node and distant metastases and also has a high mortality rate.
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Conclusion & Impact:In this publication, we discuss a case of mixed Merkel cell carcinoma and squamous cell carcinoma in the context of the contemporary literature.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Merkel cell carcinoma, also known as small cell carcinoma of the skin, is a malignant cutaneous neuroendocrin tumor. The diagnosis of this tumor is rare but it has high tendency for local recurrence, regional lymph node and distant metastases and also has a high mortality rate. For these reasons, immunohistochemical studies are necessary for making a definitive diagnosis and also for excluding a diagnosis. In this publication, we discuss a case of mixed Merkel cell carcinoma and squamous cell carcinoma in the context of the contemporary literature.

Özet

Merkel hücreli karsinom derinin küçük hücreli karsinomuolarak da bilinen malign kutanöz nöroendokrin bir tümördür. Seyrek tanı alan bu kanserin yüksek lokal nüks, bölgesel lenf nodu metastazı ve uzak metastaz eğilimi yanı sıra mortalite oranı da yüksektir. Bu sebeplerden dolayıimmünohistokimyasal çalışmalar ile kesin olarak tanın-ması veya tanının dışlanması gereklidir. Bu yazıda nadirgörülmesi nedeniyle mikst Merkel hücreli karsinom veskuamöz hücreli karsinom tanılı olgu güncel literatür eşliğinde tartışıldı.

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Cite This Article

SÜREN, D., ŞEDELE, M., SEZGİN, A., ELAL, R., YILDIRIM, M., SEZER, C. (2022). Mixed merkel cell carcinoma and squamous cell carcinoma: Case report. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 24 - Sayı: 1, 54–59. https://ajindex.com/articles/571428

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References (15)

  1. Albores-Saavedra J, Batich K, Chable-Montero F, Sagy N, Schwartz AM, Henson DE. Merkel cell carcinoma demo- graphics, morphology, and survival based on 3870 cases: a population based study. J Cutan Pathol 2010;37(1):20- 7
  2. Önal B, Ermete M, Yiğit S, Dinç Z, Tunakan M. Merkel hücreli karsinom: İki olguda ışık mikroskopik, immüno- histokimyasal ve ultrastrüktürel inceleme. Turk Derma- topathol 1995;1-2:36-40
  3. Iacocca MV, Abernethy JL, Stefanato CM, Allan AE, Bha- wan J. Mixed Merkel cell carcinoma and squamous cell carcinoma of the skin. J Am Acad Dermatol 1998;39(5 Pt 2):882-7
  4. Engels EA, Frisch M, Goedert JJ, Biggar RJ, Miller RW. Merkel cell carcinoma and HIV infection. Lancet 2002;359(9305):497-8
  5. Feng H, Shuda M, Chang Y, Moore PS. Clonal integration of a polyomavirus in human Merkel cell carcinoma. Sci- ence 2008;319(5866):1096-100
  6. Schmid C, Beham A, Feichtinger J, Auböck L, Dietze O. Recurrent and subsequently metastasizing Merkel cell carcinoma in a 7-year-old girl. Histopathology 1992;20(5):437-9
  7. Agelli M, Clegg LX, Becker JC, Rollison DE. The etiology and epidemiology of merkel cell carcinoma. Curr Probl Cancer 2010;34(1):14-37
  8. Agelli M, Clegg LX. Etiology and epidemiology of Merkel cell carcinoma. In: Sondak VK, Messina JL, Zager JS, De- conti RC, editors. Merkel cell carcinoma: a multidisci- plinary approach. London, UK: Imperial College Press; 2010
  9. Walsh NM. Primary neuroendocrine (Merkel cell) carci- noma of the skin: morphologic diversity and implica- tions thereof. Hum Pathol 2001;32(7):680-9
  10. Brenner B, Sulkes A, Rakowsky E, Feinmesser M, Yukelson A, Bar-Haim E, et al. Second neoplasms in patients with Merkel cell carcinoma. Cancer 2001;91(7):1358-62
  11. Howard RA, Dores GM, Curtis RE, Anderson WF, Travis LB. Merkel cell carcinoma and multiple primary cancers. Cancer Epidemiol Biomarkers Prev 2006;15(8):1545-9
  12. Ratner D, Nelson BR, Brown MD, Johnson TM. Merkel cell carcinoma. J Am Acad Dermatol 1993;29(2 Pt 1):143-56
  13. Gökdemir G, Küçükkaya M, Büyükbabani N, Kuzgun Ü. Merkel hücreli karsinom: İki olgu sunumu. Türkderm Deri Hastalıkları ve Frengi arşivi 2001;35(4)
  14. Calder KB, Coplowitz S, Schlauder S, Morgan MB. A case series and immunophenotypic analysis of CK20-/CK7+ primary neuroendocrine carcinoma of the skin. J Cutan Pathol 2007;34(12):918-23
  15. Veness M, Foote M, Gebski V, Poulsen M. The role of ra- diotherapy alone in patients with merkel cell carcinoma: reporting the Australian experien