Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2014 / Cilt: 25 - Sayı: 3

Retrospective evaluation of hyponatremia etiology and prognosis in patients hospitalized to emergency internal medicine service

Acil iç hastalıkları servisine hiponatremi nedeniyle yatırılan hastalarda etiyoloji ve prognozun geriye dönük değerlendirilmesi

Pages
200–202
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The results of our study suggest that the most common cause of hyponatremia in tertiary health care units is not hypotonic solutions, but rather syndrome of inappropriate ADH.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Hyponatremia is a serious clinical condition characterized by a high morbidity and mortality that shows an increasing incidence in presentation to the emergency department.
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Key Findings & Data:Methods: 118 consecutive patients with hyponatremia hospitalized to emergency internal medicine service from February 2012 to July 2013 were included in our study.
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Conclusion & Impact:Conclusion: The results of our study suggest that the most common cause of hyponatremia in tertiary health care units is not hypotonic solutions, but rather syndrome of inappropriate ADH.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: Hyponatremia is a serious clinical condition characterized by a high morbidity and mortality that shows an increasing incidence in presentation to the emergency department. We aimed to evaluate the etiology and prognosis of patients with hyponatremia hospitalized to the emergency internal medicine service. Methods: 118 consecutive patients with hyponatremia hospitalized to emergency internal medicine service from February 2012 to July 2013 were included in our study. We recorded de- mographic data, serum Na+ levels, volume status, factors that led to hyponatremia and prognosis of all patients. Results: 57 (48.3%) men and 61 (51.7%) women were included in our study. Median age was 68 years. The mean level of Na+ was 114.6±8.4 mEq/l. We detected normovolemic hyponatremia in 51 patients (43.2%), hypervolemic hyponatremia in 37 patients (31.4%) and hypovolemic hyponatremia in 30 patients (25.4%). Syndrome of inappropriate ADH was the leading cause of hyponatremia. Normovolemic patients had the highest mortality rate. Conclusion: The results of our study suggest that the most common cause of hyponatremia in tertiary health care units is not hypotonic solutions, but rather syndrome of inappropriate ADH.

Özet

Amaç: Hiponatremi acil servise başvurularda giderek artan sıklık gösteren, yüksek morbidite ve mortalite ile seyreden ciddi bir klinik durumdur. Çalışmamızda hastanemiz acil iç hastalıkları servisine yatırılan hiponatremik hastaların etiyoloji ve prognozlarını değerlendirmeyi amaçladık. Gereç ve Yöntem: Şubat 2012-Temmuz 2013 tarihleri arasında hastanemiz acil iç hastalıkları servisine yatırılan hiponatremili ardışık 118 hasta geriye dönük olarak değerlendirildi. Tüm hastaların demografik verileri, serum Na+ seviyeleri, volüm durumları, hiponatermiye yol açtığı belirlenen faktörler ve prognozları kayıt altına alındı. Bulgular: Çalışmaya 57 erkek (%48.3), 61 kadın (%51.7) hasta alındı. Median yaş 68 olarak saptandı. Hastaların ortalama Na+ düzeyi 114.6±8.4 mEq/l olarak hesaplandı. Elli bir (%43.2) hastada normovolemik, 37 (%31.4) hasta hipervolemik, 30 (%25.4) hastada hipovolemik hiponatremi tespit edildi. Uygunsuz ADH sendromu hiponatremi nedenleri arasında ilk sırada saptandı. En yüksek mortalite oranı normo- volemik hasta grubunda saptandı. Sonuç: Çalışmamızın sonuçları üçüncü basamak sağlık hizmeti veren kurumlarda en sık hiponatremi sebebinin hipotonik solüsyonlar değil uygunsuz ADH sendromu olabileceğini düşündürmektedir.

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Cite This Article

KAZAN, S., TEKÇE, M., ALİUSTAOĞLU, M., KILIÇ, D. A., GÖZEK, A. Ö., AKIN, S., ERDEM, M. E. (2022). Retrospective evaluation of hyponatremia etiology and prognosis in patients hospitalized to emergency internal medicine service. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 25 - Sayı: 3, 200–202. https://ajindex.com/articles/571390

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References (16)

  1. Baran D, Hutchinson TA. The outcome of hyponatremia in a general hospital population. Clin Nephrol 1984;22(2):72-6
  2. Chung HM, Kluge R, Schrier RW, Anderson RJ. Postopera- tive hyponatremia. A prospective study. Arch Intern Med 1986;146(2):333-6
  3. Arieff AI. Management of hyponatraemia. BMJ 1993;307(6899):305-8
  4. Hoorn EJ, Lindemans J, Zietse R. Development of severe hyponatraemia in hospitalized patients: treatment-related risk factors and inadequate management. Nephrol Dial Transplant 2006;21(1):70-6
  5. Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th ed. New York: WH Freeman; 2002
  6. Nielsen OA, Johannessen AC, Bardrum B. Oxcarbazepine-in- duced hyponatremia, a cross-sectional study. Epilepsy Res 1988;2(4):269-71
  7. Turchin A, Seifter JL, Seely EW. Clinical problem-solving. Mind the gap. N Engl J Med 2003;349(15):1465-9
  8. Weisberg LS. Pseudohyponatremia: a reappraisal. Am J Med 1989;86(3):315-8
  9. Chung HM, Kluge R, Schrier RW, Anderson RJ. Clinical as- sessment of extracellular fluid volume in hyponatremia. Am J Med 1987;83(5):905-8
  10. Kumar A. Clinical spectrum of hyponatremia in a tertiary care centre. Rajiv Gandhi University of Health Sciences, Kar- nataka, Bangalore, 2010
  11. Sweed HS. Hyponatremia among institutionalized elderly: Prevalence and associated clinical factors. Geriatrics and Gerontology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt, April 2012
  12. Bakar B, Tekkök İH. Nöroşirürji’de hiponatremi ve vaptan- lar. Kırıkkale Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Kırıkkale, Türkiye, TOBB-ETÜ Hastanesi, Nöroşirürji Bö- lümü, Ankara, Türkiye, 2011
  13. Verbalis J. Hyponatraemia. Water and salt homeostasis in health and disease. 1st ed., London: Baillière Tindall; 1989. p. 499-530
  14. Palmer BF. Hyponatremia in patients with central nervous system disease: SIADH versus CSW. Trends Endocrinol Me- tab 2003;14(4):182-7
  15. Deitelzweig SB, McCormick L. Hyponatremia in hospitalized patients: the potential role of tolvaptan. Hosp Pract (1995) 2011;39(3):87-98
  16. Smith D, Moore K, Tormey W, Baylis PH, Thompson CJ. Downward resetting of the osmotic threshold for thirst in patients with SIADH. Am J Physiol Endocrinol Metab 2004;287(5):E1019-23.