Clinical and histopathological features of the renal cell carcinomas of kidney

Key Findings & Data:Methods: The clinical and pathological records of 230 patients that were surgically treated with a diagnosis of renal tumors in our clinic in between 2005-2010 were analyzed retrospectively.

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Conclusion & Impact:More studies are needed with respect to tumor grade

🔬Design:Research Article

📍Scope:2005-2010 Verileri

⚙️Variables:Domain Parameters

Abstract

Background: Renal cell cancers (RCC) constitute about 3% of adult solid tumors and 85% of all parenchymal renal tumors. In this study, we aimed to evaluate the clinical and histopatho - logic properties of patients treated with a diagnosis of renal cell cancer. Methods: The clinical and pathological records of 230 patients that were surgically treated with a diagnosis of renal tumors in our clinic in between 2005-2010 were analyzed retrospectively. Results: The mean age of patients was 57.5 (32-84) years. Six - ty-nine (30%) of the patients were female and 161 (70%) were male. Nephron-sparing surgery was performed on 27 patients (12%) and radical surgery to 203 patients (88%). The mean tu - mor size was 6.9 cm (2-18). Thirty-four (15%) patients had me - tastases during treatment. The chromophobe cell RCC did not metastasize, but the sarkomatid variant RCC had the highest metastasis rates. Conclusion: In our study, the tumor stage and histological subtype were found to be more important in determining the clinical behavior of the tumor. More studies are needed with respect to tumor grade

Özet

Amaç:Böbrek hücreli kanserler (BHK), erişkin solid tümörle rinin %3’ünü, tüm parankimal böbrek tümörlerinin yaklaşık %85’ini oluşturur. Bu çalışmada, böbrek hücreli kanser tanı sıyla tedavi edilen hastaların klinik ve histopatololojik özel liklerinin araştırılması amaçlandı. Gereç ve Yöntem:2005-2010 yılları arasında kliniğimizde böbrek tümörü tanısı ile cerrahi olarak tedavi edilen 230 hastanın klinik ve patoloji kayıtları geriye dönük olarak in celendi. Bulgular:Hastaların yaş ortalaması 57.5 yıl (32-84) idi. Has taların 69’u kadın (%30), 161’i erkek (%70) idi. Yirmi yedi has taya (%12) nefron koruyucu cerrahi, 203 hastaya (%88) ise radikal cerrahi uygulandı. Ortalama tümör çapı 6.9 cm (2-18) olarak ölçüldü. Otuz dört (%15) hasta tedavi anında metastaz izlendi. Kromofob hücre tipli BHK’de metastaz saptanmazken en fazla sarkomatid varyantta metastaz saptandı. Sonuç:Çalışmamızda tümör evresi ve histolojik alttipin tü mörün klinik davranışını belirlemede daha önemli olduğu saptanmıştır. Tümör derecesi ile ilgili olarak ise daha fazla çalışmaya ihtiyaç vardır.

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Cite This Article

BALABAN, M., TARHAN, F., ASLAN, H., DEMIRKOL, M. K., TÜRK, A. (2022). Clinical and histopathological features of the renal cell carcinomas of kidney. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 25 - Sayı: 2, 124–126. https://ajindex.com/articles/571371

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