Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2014 / Cilt: 25 - Sayı: 3

The role of diffusion weighted mr for differentiation between benign and malign pancreatic masses

Pankreas kitlelerinin benign malign ayrımında difüzyon ağırlıklı mr görüntülemenin yeri

Pages
191–199
Publication Date
2022-10-17
DOI
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Conclusion: When compared mean values of ADC between benign and malign pancreatic masses, there were statistically significance (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: In this study, we aimed to evaluate the value of diffusion weighted MR imaging with the use of apparent diffusion coefficient (ADC) measurements on diagnosis and differentiation of benign and malignant pancreatic masses.
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Key Findings & Data:Methods: Diffusion weighted MR sequence was performed to 31 masses of 31 cases.
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Conclusion & Impact:Conclusion: When compared mean values of ADC between benign and malign pancreatic masses, there were statistically significance (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: In this study, we aimed to evaluate the value of diffusion weighted MR imaging with the use of apparent diffusion coefficient (ADC) measurements on diagnosis and differentiation of benign and malignant pancreatic masses. Methods: Diffusion weighted MR sequence was performed to 31 masses of 31 cases. In axial plan single shoot echo-planar spin echo sequence for 3 plans (x, y, z) at 3 different b values (b=0, b=500, b=1000 s/mm2) diffusion sensitive gradients were applied and diffusion weighted images and maps of ADC for the value of b=500 were obtained. During the evaluation of statistical data, between the groups for variables, Mann-Whitney U test statistical analysis was used. Results: The number of benign and malignant masses was 17 and 14, respectively. Benign masses were consisted of 8 pseudocysts, 8 undetermined, 3 mass-forming pancreatitis. Malignant masses were 8 adenocarsinoma, 3 intraductal papillary mucinous neoplasms, 3 malignant cells of unknown origins. The ADC values of pseudocysts were the highest among all pancreatic masses. Mean value of benign lesions was 2.12±0.56x10-3 mm2/s at b=500 s/mm2 and mean value of malign lesions was 1.25±0.14x10-3 mm2/s at b=500 s/mm2. Conclusion: When compared mean values of ADC between benign and malign pancreatic masses, there were statistically significance (p

Özet

Amaç: Bu çalışmada pankreas kitlelerinin, difüzyon ağırlıklı MR görüntüleme ile görünür difüzyon katsayısı (ADC) değerlerinin ölçülmesinin tanıya ve kitlelerin benign malign ayrımına katkısının değerlendirilmesi amaçlandı. Gereç ve Yöntem: Pankreas kitlesi olan 31 olgunun 31 adet kitlesine difüzyon ağırlıklı MR sekansı uygulandı. Aksiyal planda, single shot eko-planar spin eko sekansı ile her üç yönde (x, y, z), üç farklı b değerinde (b=0, b=500 ve b=1000 s/mm2) difüzyon duyarlı gradiyentler uygulanarak difüzyon ağırlıklı görüntüler ve b=500 değeri için ADC haritaları elde edildi. Verilerin istatistiksel olarak değerlendirmesi yapılırken gruplar arasındaki değişkenler için Mann-Whitney U testi kullanıldı. Bulgular: Otuz bir pankreas kitlesinin 17 tanesi benign, 14 tanesi malign özellikteydi. Benign kitlelerin sekizi psödokist, sekizi indetermine, biri kitleyi taklit eden pankreatit oluşturuyordu. Malign kitleler ise sekizi adenokarsinom, üçü intraduktal papiller musinöz neoplazi, üçü orijini bilinmeyen malign hücrelerden oluşmaktaydı. ADC ölçümleri sonucunda en yüksek değerler psödokistler aitti. B=500 s/mm2 değerinde benign kitlelerin ortalama ADC değeri, 2.12±0.56x10-3 mm2/s, malign kitlelerin ortalama 1.25±0.14x10-3 mm2/s olarak ölçüldü. Sonuç: Benign lezyonların ortalama ADC değeri malign lezyonların ortalama ADC değeri ile karşılaştırıldığında; ADC ölçümlerinin pankreas kitlelerinin malign benign ayrımında anlamlı olduğu bulundu (p

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Cite This Article

YAĞTU, M., ÖZTÜRK, Ç. T., TURAN, E. (2022). The role of diffusion weighted mr for differentiation between benign and malign pancreatic masses. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 25 - Sayı: 3, 191–199. https://ajindex.com/articles/571355

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