Journals / Cukurova Medical Journal / 2013 / Cilt: 38 - Sayı: 3

A Young Aged Myocardial Infarction with Factor V Leiden Mutation and High Lipoprotein A Level

Faktör V Leiden Mutasyonu ve Lipoprotein A Yüksekliğinin Bir Arada Olduğu Genç Yaş Miyokard İnfarktüsü

Pages
525–527
Publication Date
2013-09-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the control angiography, it was observed that stent was open.Key words:

📌 3 Key Takeaways

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Objective & Hypothesis:Summary Factor V Leiden (FVL) mutation has been shown tendency to thrombosis.
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Key Findings & Data:There are several publications that were reported that FVL mutation might be responsible for myocardial infarction especially in a young age group. 33 year old male patient was admitted to the emergency room with chest pain.
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Conclusion & Impact:In the control angiography, it was observed that stent was open.Key words:
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Faktör V Leiden mutasyonu · Lipoprotein a · Akut miyokard İnfarktüsü

Abstract

Summary Factor V Leiden (FVL) mutation has been shown tendency to thrombosis. Lipoprotein a (Lpa) is thought to be proatherogenic and prothrombotic. There are several publications that were reported that FVL mutation might be responsible for myocardial infarction especially in a young age group. 33 year old male patient was admitted to the emergency room with chest pain. Acute anterior myocardial infarction was diagnosed with electrocardiography. Coronary Angiography was performed. Coronary Angiography showed that there was a total occlusion in the proximal part of the left anterior descending artery (LAD). Other coronary arteries were normal. Complete patency was achieved with direct stent procedures in the completely occluded part of the left anterior descending coronary artery. FVL heterozygous mutation was found with polymerase chain reaction method. Elevated Lpa was found in the same period. A control angiography was done 2 months after the stent application because of recurrent anginal attacks. In the control angiography, it was observed that stent was open.Key words:

Özet

Faktör V Leiden (FVL) mutasyonunda tromboza eğilim olduğu gösterilmiştir. Lipoprotein A nın (Lpa) proaterojenik olduğu ve protrombotik olduğu düşünülmektedir. FVL mutasyonunun özellikle genç yaşlarda miyokard infarktüsünden sorumlu olabileceğine dair yayınlar vardır. 33 yaşında erkek hasta acile göğüs ağrısıyla başvurdu. Çekilen elektrokardiyografide akut anterior miyokard infarktüsü (AMİ) tanısı konularak koroner anjiyografisi yapıldı. Koroner anjiyografide sol ön inen arterin proksimalinde tam tıkanıklık saptandı. Diğer koroner arterler normal bulundu. Sol ön inen koroner arterdeki tam tıkanıklığa direk stent işlemi ile tam açıklık sağlandı. Polimeraz zincir reaksiyonu yöntemi ile FVL heterozigot mutasyonu saptandı. Aynı zamanda Lpa yüksekliği saptandı. Tekrarlayan anjinal ataklar nedeniyle 2 ay sonra yapılan kontrol anjiyografisinde stentin açık olduğu gözlendi.

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Cite This Article

YILDIZ, A., BAĞIRTAN, B., KARACA, İ. (2013). A Young Aged Myocardial Infarction with Factor V Leiden Mutation and High Lipoprotein A Level. Cukurova Medical Journal, Cilt: 38 - Sayı: 3, 525–527. https://ajindex.com/articles/57134

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References (1)

  1. Price DT, Ridker PM. Factor V Leiden Mutation and the risk for thromboembolic disease: A clinical perspective. Ann. İnt. Med. 1997; 127:895-903.