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Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2015 / Cilt: 26 - Sayı: 1

Evaluation of Dexamethasone-Haloperidol and Dexamethasone-Metoclopramide for the Treatment of Post-operative Nausea and Vomiting

Deksametazon-Haloperidol ve DeksametazonMetoklopramid Kombinasyonlarının Ameliyat Sonrası Bulantı ve Kusma Üzerine Olan Etkilerinin Karşılaştırılması

Tahsin ŞİMŞEK
Asu ÖZGÜLTEKİN
Gülşen BOSNA
Osman EKİNCİ
Dilek SUBAŞI
Berna TERZİOĞLU
Pages
35–41
Publication Date
2022-10-17
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: The evaluation of patients who experienced post-operative nausea and vomiting revealed significantly lower VDS scores in patients treated with DH or DM compared to patients who received the placebo (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Nausea and vomiting are one of the most common complications during the post-operative period.
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Key Findings & Data:Methods: Group D was treated with 5 mg IV dexamethasone prior to the induction of anesthesia; Group DH was treated with 5 mg IV dexamethasone as a bolus prior to the induction of anesthesia and 2 mg IV haloperidol 15 minutes before extubation; Group DM was treated with 5 mg IV dexamethasone prior to the induction of anesthesia and 10 mg IV metoclopramide before extubation.
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Conclusion & Impact:Results: The evaluation of patients who experienced post-operative nausea and vomiting revealed significantly lower VDS scores in patients treated with DH or DM compared to patients who received the placebo (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Nausea and vomiting are one of the most common complications during the post-operative period. The aim of the present study was to evaluate anti-emetic efficiency using the combination of dexamethasone and other commonly used antiemetic agents, haloperidol and metoclopramide. Methods: Group D was treated with 5 mg IV dexamethasone prior to the induction of anesthesia; Group DH was treated with 5 mg IV dexamethasone as a bolus prior to the induction of anesthesia and 2 mg IV haloperidol 15 minutes before extubation; Group DM was treated with 5 mg IV dexamethasone prior to the induction of anesthesia and 10 mg IV metoclopramide before extubation. Nausea-vomiting was assessed using the 5-point Verbal Descriptive Scale (VDS). Results: The evaluation of patients who experienced post-operative nausea and vomiting revealed significantly lower VDS scores in patients treated with DH or DM compared to patients who received the placebo (p

Özet

Amaç: Ameliyat sonrası dönemde en sık karşılaşılan bulantı ve kusma, ciddi bir sorun olmaya devam etmektedir. Antiemetik özelliği olan deksametazonu diğer sık kullanılan antiemetikler haloperidol ve metoklopramid ile kombine ederek etkinliklerini karşılaştırmayı amaçladık. Gereç ve Yöntem: Ameliyat sonrası dönemde bulantı kusma gözlenen hasta verileri incelendiğinde; DH ve DM kombinasyonlarının kullanıldığı hasta gruplarında, plasebo kullanılan hasta gruplarına göre, istatistiksel olarak anlamlı ölçüde daha düşük VDS değerlerinin elde edildiği görülmüştür (p

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Cite This Article

ŞİMŞEK, T., ÖZGÜLTEKİN, A., BOSNA, G., EKİNCİ, O., SUBAŞI, D., TERZİOĞLU, B. (2022). Evaluation of Dexamethasone-Haloperidol and Dexamethasone-Metoclopramide for the Treatment of Post-operative Nausea and Vomiting. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 26 - Sayı: 1, 35–41. https://ajindex.com/articles/571322

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