Geniş Yanıklı Hastalarda Yakın Akraba (Aile) Kaynaklı Deri Allogrefti Kullanımı

No donor site complications were observed.Conclusion: Especially in major burn patients without sufficient autologous donor site skin graft, close relative (family) skin grafting is an easy and cost-effective treatment method when skin banks and keratinocyte cultures are not available

📌 3 Key Takeaways

🎯

Objective & Hypothesis:Background: The aim of this study was to retrospectively evaluate results of treatment using close relative (family) skin allograft at our burn center for patients with major burns.Methods: Files of 13 patients who had severe burns and were treated with close relative (family) skin allograft at our burn center between January 1, 2016 and August 1, 2016 were examined retrospectively for age, sex, total burn surface area (TBSA), Abbreviated Burn Severity Index (ABSI) score, length of hospital stay, and mortality, as well as to obtain donor data of total count, sex, age, complications and length of stay in hospital.Results: Mean burn patient age was 24.46 (±12.65 SD) years and mean donor patent age was 35.64 (±9.34 SD).

📊

Key Findings & Data:Ten of the patients were male (76%) and 3 were female (24%).

💡

Conclusion & Impact:No donor site complications were observed.Conclusion: Especially in major burn patients without sufficient autologous donor site skin graft, close relative (family) skin grafting is an easy and cost-effective treatment method when skin banks and keratinocyte cultures are not available

🔬Design:Research Article

📍Scope:2016 Verileri

⚙️Variables:Domain Parameters

Abstract

Background: The aim of this study was to retrospectively evaluate results of treatment using close relative (family) skin allograft at our burn center for patients with major burns.Methods: Files of 13 patients who had severe burns and were treated with close relative (family) skin allograft at our burn center between January 1, 2016 and August 1, 2016 were examined retrospectively for age, sex, total burn surface area (TBSA), Abbreviated Burn Severity Index (ABSI) score, length of hospital stay, and mortality, as well as to obtain donor data of total count, sex, age, complications and length of stay in hospital.Results: Mean burn patient age was 24.46 (±12.65 SD) years and mean donor patent age was 35.64 (±9.34 SD). Ten of the patients were male (76%) and 3 were female (24%). Mean TBSA was 57.61% (±13.13 SD) and mean ABSI score was 9.07 (±2.25 SD. Mean length of hospital stay for burn patients was 53.46 (±38.62 SD) days, and 1.23 (±0.43 SD) days for donor patients. Four of the 13 burn patients (30%) died in hospital as result of burn injuries. Skin allografts were taken from just 1 close relative donor in 1 session in all cases but 1, in which skin allografts were taken from 2 close relatives in 2 sessions. Only 1 of the 14 donors was female (8%). No donor site complications were observed.Conclusion: Especially in major burn patients without sufficient autologous donor site skin graft, close relative (family) skin grafting is an easy and cost-effective treatment method when skin banks and keratinocyte cultures are not available

Özet

Amaç: Bu çalışmada yanık merkezimizde yakın akraba (aile) kaynaklı deri allogreft ile onarım uygulanan majör yanıklı hastaların geriye dönük olarak incelenmesi ve sonuçlarının değerlendirilmesi amaçlandı.Gereç ve Yöntem: 1 Ocak 2016-1 Ağustos 2016 tarihleri arasında yanık merkezimizde yakın akraba kaynaklı deri allogreft uygulanan 13 hasta çalışmaya dahil edildi. Hasta dosyaları yaş, cinsiyet dağılımı, total yanık yüzey alanı, "Abbreviated Burn Severity Index" (ABSI) skoru, hastanede kalış süresi mortalite sayısı ile donör sayısı, donör yaşı, cinsiyeti, donör alan komplikasyonları ve yatış süresi açısından geriye dönük olarak tarandı.Bulgular: Yanık hastaların yaş ortalaması 24.46 (±12.65 SS) yıl, donör hastaların yaş ortalaması ise 35.64 (±9.34 SS) yıl idi. Hastaların 10'u (%76) erkek, üçü (%24) kadındı. Total yanık yüzeyi alanı ortalaması %57.61 (±13.13 SS) olarak saptandı. ABSI skoru ortalaması 9.07 (±2.25 SS) olarak bulundu. Ortalama hastanede kalış süresi 53.4 (±38.62 SS) gün idi. Allogreft uygulanan dört (%30) hastanın hayatını kaybettiği saptandı. Yalnızca bir hasta için farklı seanslarda iki ayrı donörden allogreft alınırken, diğer hastalar için ise sadece tek donörden allogreft alındı. Donörlerin biri kadın 13'ü (%92) erkek idi. Hiçbir donörde verci alanla ilgili bir komplikasyon saptanmadı.Sonuç: Özellikle yeterli miktarda otogreft donör sahası bulunmayan majör yanıklı hastalarda deri bankası bulunmadığı ve kerotinosit kültürlerinin yapılamadığı koşullarda yakın akraba (aile) kaynaklı deri allogrefti kullanımının ulaşılması kolay ve 'cost-effective' bir yöntem olduğunu düşünmekteyiz

🔖

Cite This Article

YAMAN, M., GİDEROĞLU, K., TUNÇAY, E., TAŞDELEN, İ., KAŞIKÇI, Ö. H., FİLİNTE, G. T. (2022). Geniş Yanıklı Hastalarda Yakın Akraba (Aile) Kaynaklı Deri Allogrefti Kullanımı. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 27 - Sayı: 3, 205–209. https://ajindex.com/articles/571272

📄 Full Text PDF Viewer

Open in New Tab ↗

↗New Tab

📄

PDF görüntüleyici hazırlanıyor...

References (14)

Inouye SK, Charpentier PA. Precipitating factors for delirium in hospitalized elderly persons. Predictive model and interrelationship with baseline vulnerability. JAMA 1996;275:852-7
Moore FD. The body-weight burn budget. Basic fluid therapy for the early burn. Surg Clin North Am 1970;5:1249-65
Coruh A, Tosun Z, Ozbebit U. Close relative intermingled skin allograft and autograft use in the treatment of major burns in adults and children. J Burn Care Rehabil 2005;26:471-7
Janzekovic Z. A new concept in the early excision and immediate grafting of burns. J Trauma 1970;10:1103-8
Tobiasen J, Hiebert JM, Edlich RF. The abbreviated burn severity index. Ann Emerg Med 1982;11:260-2
Berndtson AE, Sen S, Greenhalgh DG, Palmieri TL. Estimating severity of burn in children: Pediatric Risk of Mortality (PRISM) score versus Abbreviated Burn Severity Index (ABSI). Burns 2013;39:1048-53
Bondoc CC, Burke JF. Clinical experience with viable frozen human skin and a frozen skin bank. Ann Surg 1971;174:371-82
Herndon DN. Perspectives in the use of allograft. J Burn Care Rehabil 1997;18(1 Pt 2):6
Wurzer P, Keil H, Branski LK, Parvizi D, Clayton RP, Finnerty CC, et al. The use of skin substitutes and burn care-a survey. J Surg Res 2016;201:293-8
Phipps AR, Clarke JA. The use of intermingled autograft and parental allograft skin in the treatment of major burns in children. Br J Plast Surg 1991;44:608-11
Qaryoute S, Mirdad I, Hamail AA. Usage of autograft and allograft skin in treatment of burns in children. Burns 2001;27:599-602
Hyland EJ, D'Cruz R, Menon S, Chan Q, Harvey JG, Lawrence T, et al. Prospective, randomised controlled trial comparing Versajet(TM) hydrosurgery and conventional debridement of partial thickness paediatric burns. Burns 2015;41:700-7
Castagnoli C, Alotto D, Cambieri I, Casimiri R, Aluffi M, Stella M, et al. Evaluation of donor skin viability: fresh and cryopreserved skin using tetrazolioum salt assay. Burns 2003;29:759-67
Bravo D, Rigley TH, Gibran N, Strong DM, Newman-Gage H. Effect of storage and preservation methods on viability in transplantable human skin allografts. Burns 2000;26:367-78.